-
1
-
-
33847625532
-
Dual endofhelin receptor blockade acutely improves insulin sensitivity in obese patients with insulin resistance and coronary artery disease
-
PMID:17327326, doi:10.2337/dc06-1978
-
Ahlborg, G., Shemyakin, A., Bohm, F., Gonon, A., and Pernow, J. 2007. Dual endofhelin receptor blockade acutely improves insulin sensitivity in obese patients with insulin resistance and coronary artery disease. Diabetes Care, 30: 591-596. doi:10.2337/dc06-1978. PMID:17327326.
-
(2007)
Diabetes Care
, vol.30
, pp. 591-596
-
-
Ahlborg, G.1
Shemyakin, A.2
Bohm, F.3
Gonon, A.4
Pernow, J.5
-
2
-
-
0036670305
-
Endothelin A-receptor blockade in experimental diabetes improves glucose balance and gastrointestinal function
-
PMID:12193138
-
Balsiger, B., Rickenbacher, A., Boden, P.J., Biecker, E., Tsui, J., Dashwood, M., et al. 2002. Endothelin A-receptor blockade in experimental diabetes improves glucose balance and gastrointestinal function. Clin. Sci. (Lond.), 103(Suppl 48): 430S-433S. PMID:12193138.
-
(2002)
Clin. Sci. (Lond.)
, vol.103
, Issue.SUPPL. 48
-
-
Balsiger, B.1
Rickenbacher, A.2
Boden, P.J.3
Biecker, E.4
Tsui, J.5
Dashwood, M.6
-
3
-
-
33744922911
-
Profile of past and current clinical trials involving endothelin receptor antagonists: The novel "-sentan" class of drug
-
PMID:16740981
-
Battistini, B., Berthiaume, N., Kelland, N.F., Webb, D.J., and Kohan, D.E. 2006. Profile of past and current clinical trials involving endothelin receptor antagonists: the novel "-sentan" class of drug. Exp. Biol. Med. (Maywood), 231: 653-695. PMID:16740981.
-
(2006)
Exp. Biol. Med. (Maywood)
, vol.231
, pp. 653-695
-
-
Battistini, B.1
Berthiaume, N.2
Kelland, N.F.3
Webb, D.J.4
Kohan, D.E.5
-
4
-
-
27344441662
-
Endothelin antagonism improves hepatic insulin sensitivity associated with insuhn signaling in Zucker fatty rats
-
PMID:1653642, doi:10.1016/j.metabol.2005.05.019
-
Berthiaume, N., Carlson, C.J., Rondinone, C.M., and Zinker, B.A. 2005a. Endothelin antagonism improves hepatic insulin sensitivity associated with insuhn signaling in Zucker fatty rats. Metabolism, 54: 1515-1523. doi:10.1016/j.metabol.2005.05.019. PMID:1653642.
-
(2005)
Metabolism
, vol.54
, pp. 1515-1523
-
-
Berthiaume, N.1
Carlson, C.J.2
Rondinone, C.M.3
Zinker, B.A.4
-
5
-
-
19444387417
-
Metabolic responses with endothelin antagonism in a model of insulin resistance
-
PMID:15931607, doi:10.1016/j.metabol.2004. 12.019
-
Berthiaume, N., Wessale, J.L., Opgenorth, T.J., and Zinker, B.A. 2005b. Metabolic responses with endothelin antagonism in a model of insulin resistance. Metabolism, 54: 735-740. doi:10.1016/j.metabol.2004. 12.019. PMID:15931607.
-
(2005)
Metabolism
, vol.54
, pp. 735-740
-
-
Berthiaume, N.1
Wessale, J.L.2
Opgenorth, T.J.3
Zinker, B.A.4
-
6
-
-
33645982255
-
From mice to men: Insights into the insulin resistance syndromes
-
PMID:16460269, doi:10.1146/annurev.physiol.68.040104.124723
-
Biddinger, S.B., and Kahn, C.R. 2006. From mice to men: insights into the insulin resistance syndromes. Annu. Rev. Physiol. 68:123-158. doi:10.1146/annurev.physiol.68.040104.124723. PMID:16460269.
-
(2006)
Annu. Rev. Physiol
, vol.68
, pp. 123-158
-
-
Biddinger, S.B.1
Kahn, C.R.2
-
7
-
-
0037302999
-
High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1
-
PMID:12388107
-
Chen, S., Mukherjee, S., Chakraborty, C. and Chakrabarti, S. 2003. High glucose-induced, endothelin-dependent fibronectin synthesis is mediated via NF-kappa B and AP-1. Am. J. Physiol. Cell Physiol. 284: C263-C272. PMID:12388107.
-
(2003)
Am. J. Physiol. Cell Physiol
, vol.284
-
-
Chen, S.1
Mukherjee, S.2
Chakraborty, C.3
Chakrabarti, S.4
-
8
-
-
0035095844
-
Endothelial dysfunction and salt-sensitive hypertension in spontaneously diabetic Goto-Kakizaki rats
-
PMID:11230314
-
Cheng, Z.J., Vaskonen, T., Tikkanen, I., Nurminen, K., Ruskoaho, H., Vapaatalo, H., et al. 2001. Endothelial dysfunction and salt-sensitive hypertension in spontaneously diabetic Goto-Kakizaki rats. Hypertension, 37: 433-439. PMID:11230314.
-
(2001)
Hypertension
, vol.37
, pp. 433-439
-
-
Cheng, Z.J.1
Vaskonen, T.2
Tikkanen, I.3
Nurminen, K.4
Ruskoaho, H.5
Vapaatalo, H.6
-
9
-
-
34447639753
-
Differential effects of ET(A) and ET(B) receptor antagonism on oxidative stress in type 2 diabetes
-
doi:10.1016/j.vph.2007.05.006
-
Elgebaly, M.M., Portik-Dobos, V., Sachidanandam, K., Rychly, D., Malcom, D., Johnson, M.H., and Ergul, A. 2007. Differential effects of ET(A) and ET(B) receptor antagonism on oxidative stress in type 2 diabetes. Vasc. Pharmacol. 47: 125-130. doi:10.1016/j.vph.2007.05.006.
-
(2007)
Vasc. Pharmacol
, vol.47
, pp. 125-130
-
-
Elgebaly, M.M.1
Portik-Dobos, V.2
Sachidanandam, K.3
Rychly, D.4
Malcom, D.5
Johnson, M.H.6
Ergul, A.7
-
10
-
-
20144364889
-
Vascular dysfunction of venous bypass conduits is mediated by reactive oxygen species in diabetes: Role of endothelin-1
-
PMID:15608082, doi:10.1124/jpet.104.078105
-
Ergul, A., Schultz Johansen, J., Stromhaug, C., Harris, A.K., Hutchinson, J., Tawfik, A., et al. 2004. Vascular dysfunction of venous bypass conduits is mediated by reactive oxygen species in diabetes: role of endothelin-1. J. Pharmacol. Exp. Ther. 313: 70-77. doi:10.1124/jpet.104.078105. PMID:15608082.
-
(2004)
J. Pharmacol. Exp. Ther
, vol.313
, pp. 70-77
-
-
Ergul, A.1
Schultz Johansen, J.2
Stromhaug, C.3
Harris, A.K.4
Hutchinson, J.5
Tawfik, A.6
-
11
-
-
0028063717
-
Insulin-induced activation of glycerol-3-phosphate acyltransferase by a chiro-inositol-containing insulin mediator is defective in adipocytes of insulin-resistant, type II diabetic, Goto-Kakizaki rats
-
PMID:7972005, doi:10.1073/pnas.91.23.11040
-
Farese, R.V., Standaert, M.L., Yamada, K., Huang, L.C., Zhang, C., Cooper, D.R., et al. 1994. Insulin-induced activation of glycerol-3-phosphate acyltransferase by a chiro-inositol-containing insulin mediator is defective in adipocytes of insulin-resistant, type II diabetic, Goto-Kakizaki rats. Proc. Natl. Acad. Sci. U.S.A. 91: 11040-11044. doi:10.1073/pnas.91.23.11040. PMID:7972005.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A
, vol.91
, pp. 11040-11044
-
-
Farese, R.V.1
Standaert, M.L.2
Yamada, K.3
Huang, L.C.4
Zhang, C.5
Cooper, D.R.6
-
12
-
-
0028947511
-
Plasma endothelin-1 levels in obese hypertensive and normotensive men
-
PMID:7698512, doi:10.2337/diabetes.44.4.431
-
Ferri, C., Belhni, C., Desideri, G., Di Francesco, L., Baldoncini, R., Santucci, A., and De Mattia, G. 1995. Plasma endothelin-1 levels in obese hypertensive and normotensive men. Diabetes, 44: 431-436. doi:10.2337/diabetes.44.4.431. PMID:7698512.
-
(1995)
Diabetes
, vol.44
, pp. 431-436
-
-
Ferri, C.1
Belhni, C.2
Desideri, G.3
Di Francesco, L.4
Baldoncini, R.5
Santucci, A.6
De Mattia, G.7
-
13
-
-
21744437756
-
Endothelin-mediated remodeling in aortas of diabetic rats
-
PMID:15580650, doi:10.1002/dmrr.527
-
Fukuda, C., Khan, Z.A., Barbin, Y.P., Farhangkhoee, H., Tilton, R.G., and Chakrabarti, S. 2005. Endothelin-mediated remodeling in aortas of diabetic rats. Diabetes Metab. Res. Rev. 21: 367-375. doi:10.1002/dmrr.527. PMID:15580650.
-
(2005)
Diabetes Metab. Res. Rev
, vol.21
, pp. 367-375
-
-
Fukuda, C.1
Khan, Z.A.2
Barbin, Y.P.3
Farhangkhoee, H.4
Tilton, R.G.5
Chakrabarti, S.6
-
14
-
-
0026549678
-
Increased plasma levels of endothehn in diabetic patients with hypertension
-
PMID:1575942
-
Haak, T., Jungmann, E., Felber, A., Hillmann, U., and Usadel, K.H. 1992. Increased plasma levels of endothehn in diabetic patients with hypertension. Am. J. Hypertens. 5: 161-166. PMID:1575942.
-
(1992)
Am. J. Hypertens
, vol.5
, pp. 161-166
-
-
Haak, T.1
Jungmann, E.2
Felber, A.3
Hillmann, U.4
Usadel, K.H.5
-
15
-
-
24144442641
-
Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: Role of endothelin-1
-
PMID:16123352, doi:10.2337/diabetes.54.9.2638
-
Harris, A.K., Hutchinson, J.R., Sachidanandam, K., Johnson, M.H., Dorrance, A.M., Stepp, D.W., et al. 2005. Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: role of endothelin-1. Diabetes, 54: 2638-2644. doi:10.2337/diabetes.54.9.2638. PMID:16123352.
-
(2005)
Diabetes
, vol.54
, pp. 2638-2644
-
-
Harris, A.K.1
Hutchinson, J.R.2
Sachidanandam, K.3
Johnson, M.H.4
Dorrance, A.M.5
Stepp, D.W.6
-
16
-
-
33845866857
-
Inflammation and metabolic disorders
-
PMID:17167474, doi:10.1038/nature05485
-
Hotamisligil, G.S. 2006. Inflammation and metabolic disorders. Nature, 444: 860-867. doi:10.1038/nature05485. PMID:17167474.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
17
-
-
0034744273
-
Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes
-
PMID:11342583, doi:10.1172/JCI11753
-
Ishibashi, K.I., Imamura, T., Sharma, P.M., Huang, J., Ugi, S., and Olefsky, J.M. 2001. Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes. J. Clin. Invest. 107: 1193-1202. doi:10.1172/JCI11753. PMID:11342583.
-
(2001)
J. Clin. Invest
, vol.107
, pp. 1193-1202
-
-
Ishibashi, K.I.1
Imamura, T.2
Sharma, P.M.3
Huang, J.4
Ugi, S.5
Olefsky, J.M.6
-
18
-
-
16644376310
-
The quest for a model of type II diabetes with nephropathy: The Goto Kakizaki rat
-
PMID:15593049
-
Janssen, U., Vassihadou, A., Riley, S.G., Phillips, A.O., and Floege, J. 2004. The quest for a model of type II diabetes with nephropathy: the Goto Kakizaki rat. J. Nephrol. 17: 769-773. PMID:15593049.
-
(2004)
J. Nephrol
, vol.17
, pp. 769-773
-
-
Janssen, U.1
Vassihadou, A.2
Riley, S.G.3
Phillips, A.O.4
Floege, J.5
-
19
-
-
0032719024
-
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
-
PMID:10449437, doi:10.1172/JCI5971
-
Jiang, Z.Y., Lin, Y.W., Clemont, A., Feener, E.P., Hein, K.D., Igarashi, M., et al. 1999. Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. J. Clin. Invest. 104: 447-457. doi:10.1172/JCI5971. PMID:10449437.
-
(1999)
J. Clin. Invest
, vol.104
, pp. 447-457
-
-
Jiang, Z.Y.1
Lin, Y.W.2
Clemont, A.3
Feener, E.P.4
Hein, K.D.5
Igarashi, M.6
-
20
-
-
0038575321
-
Endothelins in chronic diabetic comphcations
-
PMID:12839273, doi:10.1139/y03-053
-
Khan, Z.A., and Chakrabarti, S. 2003. Endothelins in chronic diabetic comphcations. Can. J. Physiol. Pharmacol. 81: 622-634. doi:10.1139/y03-053. PMID:12839273.
-
(2003)
Can. J. Physiol. Pharmacol
, vol.81
, pp. 622-634
-
-
Khan, Z.A.1
Chakrabarti, S.2
-
21
-
-
33847404040
-
Endothelin limits insulin action in obese/insulin-resistant humans
-
PMID:17327443, doi:10.2337/db06-1406
-
Lteif, A., Vaishnava, P., Baron, A.D., and Mather, K.J. 2007. Endothelin limits insulin action in obese/insulin-resistant humans. Diabetes, 56: 728-734. doi:10.2337/db06-1406. PMID:17327443.
-
(2007)
Diabetes
, vol.56
, pp. 728-734
-
-
Lteif, A.1
Vaishnava, P.2
Baron, A.D.3
Mather, K.J.4
-
22
-
-
0036311315
-
Enhanced endothelin activity prevents vasodilation to insulin in insulin resistance
-
PMID:12105142, doi:10.1161/01.HYP.0000022806.87281.62
-
Miller, A.W., Tulbert, C., Puskar, M., and Busija, D.W. 2002. Enhanced endothelin activity prevents vasodilation to insulin in insulin resistance. Hypertension, 40: 78-82. doi:10.1161/01.HYP.0000022806.87281.62. PMID:12105142.
-
(2002)
Hypertension
, vol.40
, pp. 78-82
-
-
Miller, A.W.1
Tulbert, C.2
Puskar, M.3
Busija, D.W.4
-
23
-
-
0030849449
-
Exogenous endothelin-1 causes peripheral insulin resistance in healthy humans
-
PMID:9366964, doi:10.1046/j.1365-201X.1997. 00212.x
-
Ottosson-Seeberger, A., Lundberg, J.M., Alvestrand, A., and Ahlborg, G. 1997. Exogenous endothelin-1 causes peripheral insulin resistance in healthy humans. Acta Physiol. Scand. 161: 211-220. doi:10.1046/j.1365-201X.1997. 00212.x. PMID:9366964.
-
(1997)
Acta Physiol. Scand
, vol.161
, pp. 211-220
-
-
Ottosson-Seeberger, A.1
Lundberg, J.M.2
Alvestrand, A.3
Ahlborg, G.4
-
24
-
-
33744906508
-
Microvascular versus macrovascular dysfunction in type 2 diabetes: Differences in contractile responses to endothelin-1
-
PMID:16741041
-
Sachidanandam, K., Harris, A., Hutchinson, J., and Ergul, A. 2006. Microvascular versus macrovascular dysfunction in type 2 diabetes: differences in contractile responses to endothelin-1. Exp. Biol. Med. (Maywood), 231: 1016-1021. PMID:16741041.
-
(2006)
Exp. Biol. Med. (Maywood)
, vol.231
, pp. 1016-1021
-
-
Sachidanandam, K.1
Harris, A.2
Hutchinson, J.3
Ergul, A.4
-
25
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
PMID:11742412, doi:10.1038/414799a
-
Saltiel, A.R., and Kahn, C.R. 2001. Insulin signalling and the regulation of glucose and lipid metabolism. Nature, 414: 799-806. doi:10.1038/414799a. PMID:11742412.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
26
-
-
33645641243
-
Type-2 diabetes-induced changes in vascular extracellular matrix gene expression: Relation to vessel size
-
PMID:16503991, doi:10.1186/1475-2840-5-3
-
Song, W., and Ergul, A. 2006. Type-2 diabetes-induced changes in vascular extracellular matrix gene expression: Relation to vessel size. Cardiovasc. Diabetol. 5: 3. doi:10.1186/1475-2840-5-3. PMID:16503991.
-
(2006)
Cardiovasc. Diabetol
, vol.5
, pp. 3
-
-
Song, W.1
Ergul, A.2
-
27
-
-
2942530449
-
Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states
-
PMID:15069067, doi:10.1074/jbc.M402440200
-
Standaert, M.L., Sajan, M.P., Miura, A., Kanoh, Y., Chen, H.C., Farese, R.V., Jr., and Farese, R.V. 2004. Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states. J. Biol. Chem. 279: 24929-24934. doi:10.1074/jbc.M402440200. PMID:15069067.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 24929-24934
-
-
Standaert, M.L.1
Sajan, M.P.2
Miura, A.3
Kanoh, Y.4
Chen, H.C.5
Farese Jr., R.V.6
Farese, R.V.7
-
28
-
-
0025361407
-
Elevated plasma endothelin in patients with diabetes mellitus
-
PMID:2198188, doi:10.1007/BF00403325
-
Takahashi, K., Ghatei, M.A., Lam, H.C., O'Halloran, D.J., and Bloom, S.R. 1990. Elevated plasma endothelin in patients with diabetes mellitus. Diabetologia, 33: 306-310. doi:10.1007/BF00403325. PMID:2198188.
-
(1990)
Diabetologia
, vol.33
, pp. 306-310
-
-
Takahashi, K.1
Ghatei, M.A.2
Lam, H.C.3
O'Halloran, D.J.4
Bloom, S.R.5
-
29
-
-
0344305782
-
Insulin signaling in health and disease
-
PMID:14657487, doi:10.1126/science.1092952
-
White, M.F. 2003. Insulin signaling in health and disease. Science, 302: 1710-1711. doi:10.1126/science.1092952. PMID:14657487.
-
(2003)
Science
, vol.302
, pp. 1710-1711
-
-
White, M.F.1
-
30
-
-
0043268837
-
Chronic endothelin-1 treatment leads to insulin resistance in vivo
-
PMID:12882904, doi:10.2337/diabetes.52.8.1904
-
Wilkes, J.J., Hevener, A., and Olefsky, J. 2003. Chronic endothelin-1 treatment leads to insulin resistance in vivo. Diabetes, 52: 1904-1909. doi:10.2337/diabetes.52.8.1904. PMID:12882904.
-
(2003)
Diabetes
, vol.52
, pp. 1904-1909
-
-
Wilkes, J.J.1
Hevener, A.2
Olefsky, J.3
|