Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: A case-control study on gastric and colorectal cancers in the Japanese population

American Journal of Gastroenterology

Volumn 103, Issue 6, 2008, Pages 1476-1487

  Ikeda, Shinobu ^a   Sasazuki, Shizuka ^b   Natsukawa, Syusuke ^c   Shaura, Kozo ^d   Koizumi, Yoichi ^e   Kasuga, Yoshio ^f   Ohnami, Sumiko ^g   Sakamoto, Hiromi ^g   Yoshida, Teruhiko ^g   Iwasaki, Motoki ^b   Tsugane, Shoichiro ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL CANCER CENTER   (Japan)

^c Hokushin General Hospital   (Japan)

^d Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare   (Japan)

^e Shinonoi General Hospital   (Japan)

^f Nagano Matsushiro General Hospital   (Japan)

^g NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID;

ADULT; AGED; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; COLORECTAL CANCER; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEMOGRAPHY; ENVIRONMENTAL FACTOR; FEMALE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; JAPAN; LIFESTYLE MODIFICATION; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STOMACH CANCER; TUMOR GENE;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; COHORT STUDIES; COLORECTAL NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; JAPAN; LIFE STYLE; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; STOMACH NEOPLASMS;

EID: 44949234474     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2008.01810.x     Document Type: Article

References (40)

1. Hara M, Hanaoka T, Kobayashi M, et al. Cruciferous vegetables, mushrooms, and gastrointestinal cancer risks in a multicenter, hospital-based case-control study in Japan. Nutr Cancer 2003 46 : 138 47.
2. Tsukino H, Hanaoka T, Otani T, et al. hOGG1 Ser326Cys polymorphism, interaction with environmental exposures, and gastric cancer risk in Japanese populations. Cancer Sci 2004 95 : 977 83.
3. Mohlke KL, Erdos MR, Scott LJ, et al. High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools. Proc Natl Acad Sci U S A 2002 99 : 16928 33.
4. Ross P, Hall L, Smirnov I, et al. High level multiplex genotyping by MALDI-TOF mass spectrometry. Nat Biotechnol 1998 16 : 1347 51.
5. Yoshimura K, Hanaoka T, Ohnami S, et al. Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: Data from population-based Japanese random samples. J Hum Genet 2003 48 : 654 8.
6. Applied Biosystems. myScience home page. Available at : http://www.appliedbiosystems.co.jp. Accessed February 8, 2008.
7. Schlesselman JJ. Case-control studies: Design, conduct, analysis. New York, NY : Oxford University Press, 1982.
8. Fraser AG. Pharmacokinetic interactions between alcohol and other drugs. Clin Pharmacokinet 1997 33 : 79 90.
9. Yokoyama A, Muramatsu T, Omori T, et al. Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics. Carcinogenesis 2001 22 : 433 9.
10. Yokoyama A, Watanabe H, Fukuda H, et al. Multiple cancers associated with esophageal and oropharyngolaryngeal squamous cell carcinoma and the aldehyde dehydrogenase-2 genotype in male Japanese drinkers. Cancer Epidemiol Biomarkers Prev 2002 11 : 895 900.
11. Mulligan CJ, Robin RW, Osier MV, et al. Allelic variation at alcohol metabolism genes (ADH1B, ADH1C, ALDH2) and alcohol dependence in an American Indian population. Hum Genet 2003 113 : 325 36.
12. Wu X, Hudmon KS, Detry MA, et al. D2 dopamine receptor gene polymorphisms among African-Americans and Mexican-Americans: A lung cancer case-control study. Cancer Epidemiol Biomarkers Prev 2000 9 : 1021 6.
13. Yoshida K, Hamajima N, Kozaki K, et al. Association between the dopamine D2 receptor A2/A2 genotype and smoking behavior in the Japanese. Cancer Epidemiol Biomarkers Prev 2001 10 : 403 5.
14. Shields PG, Lerman C, Audrain J, et al. Dopamine D4 receptors and the risk of cigarette smoking in African-Americans and Caucasians. Cancer Epidemiol Biomarkers Prev 1998 7 : 453 8.
15. Schulz WA, Krummeck A, Rosinger I, et al. Increased frequency of a null-allele for NAD(P)H:quinone oxidoreductase in patients with urological malignancies. Pharmacogenetics 1997 7 : 235 9.
16. Clairmont A, Sies H, Ramachandran S, et al. Association of NAD(P)H:quinone oxidoreductase (NQO1) null with numbers of basal cell carcinomas: Use of a multivariate model to rank the relative importance of this polymorphism and those at other relevant loci. Carcinogenesis 1999 20 : 1235 40.
17. Wiemels JL, Pagnamenta A, Taylor GM, et al. for the United Kingdom Childhood Cancer Study Investigators. A lack of a functional NAD(P)H:quinone oxidoreductase allele is selectively associated with pediatric leukemias that have MLL fusions. Cancer Res 1999 59 : 4095 9.
18. Lafuente MJ, Casterad X, Trias M, et al. NAD(P)H:quinone oxidoreductase-dependent risk for colorectal cancer and its association with the presence of K-ras mutations in tumors. Carcinogenesis 2000 21 : 1813 9.
19. Sarbia M, Bitzer M, Siegel D, et al. Association between NAD(P)H:quinone oxidoreductase 1 (NQO1) inactivating C609T polymorphism and adenocarcinoma of the upper gastrointestinal tract. Int J Cancer 2003 107 : 381 6.
20. Zhang JH, Li Y, Wang R, et al. NQO1 C609T polymorphism associated with esophageal cancer and gastric cardiac carcinoma in North China. World J Gastroenterol 2003 9 : 1390 3.
21. Goode EL, Dunning AM, Kuschel B, et al. Effect of germ-line genetic variation on breast cancer survival in a population-based study. Cancer Res 2002 62 : 3052 7.
22. Rosvold EA, McGlynn KA, Lustbader ED, et al. Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking. Pharmacogenetics 1995 5 : 199 206.
23. Chen H, Lum A, Seifried A, et al. Association of the NAD(P)H:quinone oxidoreductase 609C->T polymorphism with a decreased lung cancer risk. Cancer Res 1999 59 : 3045 8.
24. Hamajima N, Matsuo K, Iwata H, et al. NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism and the risk of eight cancers for Japanese. Int J Clin Oncol 2002 7 : 103 8.
25. Sharp L, Little J. Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: A HuGE review. Am J Epidemiol 2004 159 : 423 43.
26. Ulrich CM, Bigler J, Velicer CM, et al. Searching expressed sequence tag databases: Discovery and confirmation of a common polymorphism in the thymidylate synthase gene. Cancer Epidemiol Biomarkers Prev 2000 9 : 1381 5.
27. Chu J, Dolnick BJ. Natural antisense (rTSalpha) RNA induces site-specific cleavage of thymidylate synthase mRNA. Biochim Biophys Acta 2002 1587 : 183 93.
28. Zhang J, Cui Y, Kuang G, et al. Association of the thymidylate synthase polymorphisms with esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma. Carcinogenesis 2004 25 : 2479 85.
29. Gao CM, Takezaki T, Wu JZ, et al. Polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase genes and the susceptibility to esophageal and stomach cancer with smoking. Asian Pac J Cancer Prev 2004 5 : 133 8.
30. Graziano F, Kawakami K, Watanabe G, et al. Association of thymidylate synthase polymorphisms with gastric cancer susceptibility. Int J Cancer 2004 112 : 1010 4.
31. Sachse C, Brockmoller J, Bauer S, et al. Functional significance of a C->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. Br J Clin Pharmacol 1999 47 : 445 9.
32. Boobis AR, Lynch AM, Murray S, et al. CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans. Cancer Res 1994 54 : 89 94.
33. Ishibe N, Sinha R, Hein DW, et al. Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas. Pharmacogenetics 2002 12 : 145 50.
34. Le Marchand L, Hankin JH, Wilkens LR, et al. Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 2001 10 : 1259 66.
35. Hassett C, Aicher L, Sidhu JS, et al. Human microsomal epoxide hydrolase: Genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet 1994 3 : 421 8.
36. Harrison DJ, Hubbard AL, MacMillan J, et al. Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer. Br J Cancer 1999 79 : 168 71.
37. Cortessis V, Siegmund K, Chen Q, et al. A case-control study of microsomal epoxide hydrolase, smoking, meat consumption, glutathione S-transferase M3, and risk of colorectal adenomas. Cancer Res 2001 61 : 2381 5.
38. Tiemersma EW, Bunschoten A, Kok FJ, et al. Effect of SULT1A1 and NAT2 genetic polymorphism on the association between cigarette smoking and colorectal adenomas. Int J Cancer 2004 108 : 97 103.
39. Le Marchand L, Donlon T, Hankin JH, et al. B-vitamin intake, metabolic genes, and colorectal cancer risk (United States). Cancer Causes Control 2002 13 : 239 48.
40. Stolzenberg-Solomon RZ, Qiao YL, Abnet CC, et al. Esophageal and gastric cardia cancer risk and folate- and vitamin B(12)-related polymorphisms in Linxian, China. Cancer Epidemiol Biomarkers Prev 2003 12 : 1222 6.