Buflomedil for intermittent claudication

Cochrane Database of Systematic Reviews

Volumn , Issue 1, 2008, Pages

  De Backer, Tine L M ^a   Bogaert, M ^b   Vander Stichele, R ^b  

^a GHENT UNIVERSITY   (Belgium)

^b NONE

Author keywords

Administration, oral; Double blind method; Humans; Intermittent claudication *drug therapy ; Publication bias; Pyrrolidines *therapeutic use ; Randomized controlled trials as topic; Treatment outcome; Vasodilator agents *therapeutic use

Indexed keywords

BUFLOMEDIL; PLACEBO;

ARTERY DISEASE; BUERGER DISEASE; CARDIOVASCULAR RISK; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DATA ANALYSIS; DATA EXTRACTION; DIABETES MELLITUS; DRUG EFFICACY; HUMAN; INFORMATION PROCESSING; INTERMITTENT CLAUDICATION; RANDOMIZED CONTROLLED TRIAL; REVIEW; SYSTEMATIC REVIEW; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; WALKING;

EID: 44949221705     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD000988.pub3     Document Type: Review

References (38)

1. Diamantopoulos 2001 {published data only} *Diamantopoulos EJ, Grigoriadou M, Ifanti G, Raptis SA. Clinical and hemorheological effects of buflomedil in diabetic subjects with intermittent claudication. International Angiology 2001;20(4):337-44.
2. Diamantopoulos EJ, Raptis SA, Christodoulou-Peters M, Moulopoulos SD. Controlled trial of buflomedil in diabetic peripheral occlusive disease. Ischaemic Diseases and the Microcirculation. New Results. International Symposium. Frankfurt: January 1989:80-4.
3. Trübestein 1984 {published data only} Trubestein G, Balzer K, Bisler H, Kluken N, Mahfoud Y, Muller-Wiefel H, et al.Buflomedil in obstructive arterial disease: Results of a controlled trial [Buflomedil bei arterieller Verschlusskrankheit: Ergebnissse einer kontrollierten Studie]. Deutsche Medizinische Wochenschrift 1982;107(51-52):1957-61. [MEDLINE: 605].
4. *Trübestein G, Balzer K, Bisler H, Klüken N, Muller-Wiefel H, Unkel B, et al.Buflomedil in arterial occlusive disease: results of a controlled multicenter study. Angiology 1984;35(8): 500-5. [MEDLINE: 1984305153].
5. Bisler 1983 Bisler H. Clinical response to buflomedil in arterial occlusive disease. Therapiewoche 1983;33:2204-10.
6. Fonseca 1988 Fonseca V, Mikhaildis DP, Barradas MA, Jeremy JY, Gracey L, Dandona P. Double-blind placebo-controlled trial of buflomedil in intermittent claudication. International Journal of Clinical Pharmacology Research 1988;8(5):377-81. [MEDLINE: 1989154808].
7. Levien 1983 Levien. [Unpublished study] W80-BU-004LJL. S-Africa, 1983. Mentioned in: Walker GA, Mac Hannaford JC. A meta-analysis of randomized, double-blind, placebo-controlled studies of the effect of buflomedil on intermittent claudication. Fundamental & Clinical Pharmacology 1995;9(4):387-94.
8. Lowe 1987 Lowe GDO, Dandona P, Horrocks M, Cotton LT. [Unpublished study] Evaluation of the clinical efficacy and safety of oral buflomedil hydrochloride in the treatment of intermittent claudication. Study QL/UK.83/2-5. UK, 1987. Mentioned in: Walker GA, Mac Hannaford JC. A meta-analysis of randomized, double-blind, placebo-controlled studies of the effect of buflomedil on intermittent claudication. Fundamental & Clinical Pharmacology 1995;9(4):387-94 (Available from the authors).
9. Lund 1988 Lund, et al.[Unpublished study] AB-8603. US, 1988. Mentioned in: Walker GA, Mac Hannaford JC. A meta-analysis of randomized, double-blind, placebo-controlled studies of the effect of buflomedil on intermittent claudication. Fundamental & Clinical Pharmacology 1995;9(4):387-94.
10. Olsson 1986 Olsson. [Unpublished study] Sweden, 1986. Mentioned in: Walker GA, Mac Hannaford JC. A meta-analysis of randomized, double-blind, placebo-controlled studies of the effect of buflomedil on intermittent claudication. Fundamental & Clinical Pharmacology 1995;9(4):387-94.
11. Raithel 1985 Raithel, et al.[Unpublished study] BU-3-P05. Germany, 1985. Mentioned in: Walker GA, Mac Hannaford JC. A meta-analysis of randomized, double-blind, placebo-controlled studies of the effect of buflomedil on intermittent claudication. Fundamental & Clinical Pharmacology 1995;9(4):387-94.
12. Zinnagl 1986 Zinnagl N. A double blind study of the effects of buflomedil in 40 patients with arterial occlusive disease in Stage IIB [Doppelblindstudie über die Wirksamkeit von Buflomedil an 40 Patienten mit arterieller Verschlusskrankheit im Stadium IIB]. International Symposium on Conservative Therapy of Arterial Occlusive Disease. Bonn, May 23-25. New York: Georg Thieme Verlag, 1986.
13. ACC 2000 American College of Cardiology. ACC 54th annual scientific session late-breaking clinical trials. www.acc.org/media/ session_info/late/ACC05/lbct_tuesday.htm (accessed 25 October 2007).
14. Baitsch 1983 Baitsch R. [Unpublished study]. BU-2-DO2. Germany, 1983. Mentioned in: Walker GA, Mac Hannaford JC. A meta-analysis of randomized, double-blind, placebo-controlled studies of the effect of buflomedil on intermittent claudication. Fundamental & Clinical Pharmacology 1995; Vol. 9, issue 4:387-94.
15. Bevan 1992 Bevan EG, Waller PC, Ramsay LE. Pharmacological approaches to the treatment of intermittent claudication. Drugs & Aging 1992;2(2):125-36.
16. Cameron 1988 Cameron HA, Waller PC, Ramsay LE. Drug treatment of intermittent claudication: critical analysis of the methods and findings of published clinical trials, 1965-1985. British Journal of Clinical Pharmacology 1988;26(5):569-76.
17. Diamantopoulos 1989 Diamantopoulos EJ, Raptis SA, Christodoulou-Peters M, Moulopoulos SD. Controlled trial of buflomedil in diabetic peripheral occlusive disease. Ischaemic diseases and the microcirculation. New results. International Symposium. Frankfurt: January 1989:80-4.
18. Dickersin 1994 Dickersin K, Scherer R, Lefebvre C. Identifying relevant studies for systematic reviews. BMJ 1994;309(6964):1286- 91.
19. Fontaine 1954 Fontaine VR, Kim M, Kieny R. Surgical treatment for peripheral vascular disease [Die chirurgische Behandlung der peripheren Durchblutungsstorungen]. Helvetica Chirurgica Acta 1954;5/6:499- 533.
20. Gardner 1989a Gardner MJ, Altman DG. Estimating with confidence. In: GardnerMJ, AltmanDG editor(s). Statistics with confidence: confidence intervals and statistical guidelines. London: BMJ Publishing Group, 1989:3-5.
21. Gardner 1989b Gardner MJ, Altman DG. Estimation rather than hypothesis testing: confidence intervals rather than P values. In: GardnerMJ, AltmanDG editor(s). Statistics with confidence: confidence intervals and statistical guidelines. London: BMJ Publishing Group, 1989:6-19.
22. Gardner 1989c Altman DG, Gardner MJ. Calculating confidence intervals for means and their differences. In: GardnerMJ, AltmanDG editor(s). Statistics with confidence: confidence intervals and statistical guidelines. London: BMJ Publishing Group, 1989:20-7.
23. Gardner 1989d Gardner MJ, Altman DG. Tables for calculation of confidence intervals. In: GardnerMJ, AltmanDG editor(s). Statistics with confidence: confidence intervals and statistical guidelines. London: BMJ Publishing Group, 1989:111-29.
24. Jadad 1996 Jadad RJ, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al.Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Controlled Clinical Trials 1996;17:1-12.
25. Jepson 2006 Jepson RG, Kleijnen J, Leng GC. Garlic for peripheral arterial occlusive disease. Cochrane Database of Systematic Reviews 2006, Issue 4. Art. No.: CD000095. DOI: 10.1002/14651858.CD000095.Art. No.: CD000095. DOI:10.1002/14651858.CD000095.
26. Kleijnen 2005 Kleijnen J, Mackerras D. Vitamin E for intermittent claudication. Cochrane Database of Systematic Reviews 2005, Issue 1. Art. No.: CD000987. DOI: 10.1002/14651858.CD000987.Art. No.: CD000987. DOI:10.1002/14651858.CD000987.
27. Leng 2005 Leng GC, Fowler B, Ernst E. Exercise for intermittent claudication. Cochrane Database of Systematic Reviews 2005, Issue 1. Art. No.: CD000990. DOI: 10.1002/14651858.CD000990.Art. No.: CD000990. DOI:10.1002/14651858.CD000990.
28. Liard 1997 Liard F, Benichou AC, Gamand S, Lehert P. The effects of naftidrofuryl on quality of life. Disease Management Health Outcomes 1997;2(Suppl 1):71-8.
29. Marimbert 2006 Marimbert J. Lettre aux professionnels de santé: Pharmacovigilance et la sécurité d'emploi du buflomédil [Letter to health professionals: Pharmacovigilance and safety of use of buflomedil]. Agence française de sécurité sanitaire des produits de santé 13 November 2006.
30. Mulrow 1999 Mulrow CD, Oxman AD. Cochrane Collaboration Handbook (In: The Cochrane Library, Issue 3). Oxford: Update Software, 1999.
31. Price 2005 Price JF, Leng GC. Steroid sex hormones for lower limb atherosclerosis. Cochrane Database of Systematic Reviews 2005, Issue 2. Art. No.: CD000188. DOI: 10.1002/14651858.CD000188.Art. No.: CD000188. DOI:10.1002/14651858.CD000188.
32. Schulz 1995 Schulz KF, Chalmers IC, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. Journal of the American Medical Association 1995;273(5):408-12.
33. Spengel 1997 Spengel A, Brown TM, Dietze S, Kirchberger I, Comte S. The claudication scale (CLAU-S). New disease-specific quality-of-life instrument in intermittent claudication. Disease Management Health Outcomes 1997;2(Suppl 1):65-70.
34. Verhaeghe 1998 Verhaeghe R. Epidemiology and prognosis of peripheral obliterative arteriopathy. Drugs 1998;56(suppl 3):1-10.
35. Walker 1995 Walker GA, Mac Hannaford JC. A meta-analysis of randomized, double-blind, placebo-controlled studies of the effect of buflomedil on intermittent claudication. Fundamental & Clinical Pharmacology 1995;9(4):387-94.
36. Wood 2005 Wood S. Buflomedil to reduce clinical complications of peripheral artery disease? Maybe, maybe not. www.theheart.org/article/402581.do 11 March 2005, issue accessed 26 April 2007.
37. Wurzinger 1987 Wurzinger LJ, Schmid-Schonbein H. Effect of buflomedil on epinephrine-enhanced platelet aggregation in vitro and ex vivo. Arzneimittel-Forschung 1987;37(10):1113-5.
38. De Backer 2000 De Backer TLM, Vander Stichele RH, Bogaert MG. Buflomedil for intermittent claudication. Cochrane Database of Systematic Reviews 2000, Issue 2. Art. No.: CD000988. DOI: 10.1002/14651858.CD000988. Art. No.: CD000988. DOI:10.1002/14651858.CD000988.pub3.