The hyperenergetic-fed obese dog, a model of disturbance of apolipoprotein B-100 metabolism associated with insulin resistance: kinetic study using stable isotopes

Metabolism: Clinical and Experimental

Volumn 57, Issue 7, 2008, Pages 966-972

  Briand, François ^a,b   Bailhache, Edwige ^a,b   Andre, Agnes ^a,c   Magot, Thierry ^a   Krempf, Michel ^a   Nguyen, Patrick ^b   Ouguerram, Khadija ^a  

^a INSERM   (France)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c Prologue Biotech   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B100; LOW DENSITY LIPOPROTEIN; STABLE ISOTOPE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; INSULIN RESISTANCE; KINETICS; LIPOLYSIS; MASS FRAGMENTOGRAPHY; NONHUMAN; OBESITY; PRIORITY JOURNAL;

ANIMALS; APOLIPOPROTEIN B-100; BLOOD GLUCOSE; CHOLESTEROL; DIET; DOGS; ENERGY INTAKE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; INSULIN; INSULIN RESISTANCE; KINETICS; LEUCINE; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; OBESITY;

EID: 44949221335     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2008.02.013     Document Type: Article

References (42)

1. Bamba V., and Rader D.J. Obesity and atherogenic dyslipidemia. Gastroenterology 132 (2007) 2181-2190
2. Riccardi G., Giacco R., and Rivellese A.A. Dietary fat, insulin sensitivity and the metabolic syndrome. Clin Nutr 23 (2004) 447-456
3. Li J., Tian H., Li Q., et al. Improvement of insulin sensitivity and beta-cell function by nateglinide and repaglinide in type 2 diabetic patients-a randomized controlled double-blind and double-dummy multicentre clinical trial. Diabetes Obes Metab 9 (2007) 558-565
4. Karlsson H.K., and Zierath J.R. Insulin signaling and glucose transport in insulin resistant human skeletal muscle. Cell Biochem Biophys 48 (2007) 103-113
5. Trout K.K., Homko C., and Tkacs N.C. Methods of measuring insulin sensitivity. Biol Res Nurs 8 (2007) 305-318
6. Leung N., Naples M., Uffelman K., et al. Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster. An animal model of nutritionally-induced insulin resistance. Atherosclerosis 174 (2004) 235-241
7. Nandi A., Kitamura Y., Kahn C.R., et al. Mouse models of insulin resistance. Physiol Rev 84 (2004) 623-647
8. Tofovic S.P., and Jackson E.K. Rat models of the metabolic syndrome. Methods Mol Med 86 (2003) 29-46
9. Xi S., Yin W., Wang Z., et al. A minipig model of high fat/high-sucrose diet-induced diabetes and atherosclerosis. Int J Exp Pathol 85 (2004) 223-231
10. Bailhache E., Nguyen P., Krempf M., et al. Lipoproteins abnormalities in obese insulin-resistant dogs. Metabolism 52 (2003) 559-564
11. Chahil T.J., and Ginsberg H.N. Diabetic dyslipidemia. Endocrinol Metab Clin North Am 35 (2006) 491-510
12. Briand F., Bailhache E., Nguyen P., et al. Metabolism of high density lipoprotein apolipoprotein A-I and cholesteryl ester in insulin resistant dog: a stable isotope study. Diabetes Obes Metab 9 (2007) 139-142
13. Kissebah A.H., Alfarsi S., Evans D.J., et al. Integrated regulation of VLDL triglyceride and apolipoprotein B kinetics non-insulin-dependant diabetes mellitus. Diabetes 31 (1982) 217-224
14. Zoltowska M., Ziv E., Delvin E., et al. Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly. Arterioscler Thromb Vasc Biol 24 (2004) 118-123
15. Haidari M., Leung N., Mahbub F., et al. Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and apoB48-containing lipoprotein overproduction. J Biol Chem 277 (2002) 31646-31655
16. Bailhache E., Ouguerram K., Gayet C., et al. An insulin-resistant hypertriglyceridaemic normotensive obese dog model: assessment of insulin resistance by the euglycaemic hyperinsulinaemic clamp in combination with the stable isotope technique. J Anim Physiol Anim Nutr 87 (2003) 86-95
17. Havel R.J., Eder A., and Bragdon J.H. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34 (1955) 1345-1353
18. Mahley R.W., and Weisgraber K.H. Canine lipoproteins and atherosclerosis. I. Isolation and characterization of plasma lipoproteins from control dogs. Circ Res 35 (1974) 713-721
19. Barrie J., Nash A.S., and Watson T.D.G. Quantitative analysis of canine plasma lipoproteins. J Small Anim Pract 34 (1993) 226-231
20. Egusa G., Brady D.W., Grundy S.M., et al. Isopropanol precipitation method for the determination of apolipoprotein B specific activity and plasma concentrations during metabolic studies of very low density lipoprotein and low density lipoprotein apolipoprotein B. J Lipid Res 24 (1983) 1261-1267
21. Beghin L., Duhal N., Poulain P., et al. Measurement of apolipoprotein B concentration in plasma lipoproteins by combining selective precipitation and mass spectrometry. J Lipid Res 41 (2000) 1172-1176
22. Yao Z., and McLeod R.S. Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins. Biochim Biophys Acta 1212 (1994) 152-166
23. Cobelli C., Toffolo G., Bier D.M., et al. Models to interpret kinetic data in stable isotope tracer studies. Am J Physiol 253 (1987) 551-564
24. Maugeais C., Ouguerram K., Krempf M., et al. Kinetic study of apo B100 containing lipoprotein metabolism using amino acids labeled with stable isotopes: methodological aspects. Clin Chem Lab Med 36 (1998) 739-745
25. Bailhache E., Briand F., Nguyen P., et al. Metabolism of cholesterol ester of apolipoprotein B100-containing lipoproteins in dogs: evidence for disregarding cholesterol ester transfer. Eur J Clin Invest 34 (2004) 527-534
26. Ouguerram K., Magot T., Zair Y., et al. Effect of atorvastatin on apolipoprotein B100 containing lipoprotein metabolism in type-2 diabetes. J Pharmacol Exp Ther 306 (2003) 332-337
27. Swanson K.S., Kuzmuk K.N., Schook L.B., and Fahey Jr. G.C. Diet affects nutrient digestibility, hematology, and serum chemistry of senior and weanling dogs. J Anim Sci 82 (2004) 1713-1724
28. Sokal R.R., and Rohlf F.J. Miscellaneous methods. In: Freeman W.H. (Ed). Biometry. The principles and practice of statistics in biological research. 3rd ed. (1995), Freeman, New York 797-803
29. Akaike H. A new look at the statistical model identification. IEEE Trans Automat Contr AC 19 (1974) 710-716
30. Boxenbaum H.G., Tiegelman N., and Elastoff R.M. Statistical estimation in pharmacokinetics. J Pharmacokinet Biopharm 2 (1974) 123-148
31. Sparks J.D., and Sparks C.E. Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes. J Biol Chem 265 (1990) 8854-8862
32. Zoltowska M., Ziv E., Delvin E., et al. Cellular aspects of intestinal lipoprotein assembly in Psammomys obesus: a model of insulin resistance and type 2 diabetes. Diabetes 52 (2003) 2539-2545
33. Kuriyama H., Yamashita S., Shimomura I., et al. Enhanced expression of hepatic acyl-coenzyme A synthetase and microsomal triglyceride transfer protein messenger RNAs in the obese and hypertriglyceridemic rat with visceral fat accumulation. Hepatology 27 (1998) 557-562
34. Taghibiglou C., Carpentier A., Van Iderstine S.C., et al. Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance: evidence for enhanced lipoprotein assembly. Reduced intracellular ApoB degradation. and increased microsomal triglyceride transfer protein in a fructose-fed hamster model. J Biol Chem 275 (2000) 8416-8425
35. Taskinen M.R., Packard C.J., and Shepherd J. Effect of insulin therapy on metabolic fate of apolipoprotein-B containing lipoproteins in NIDDM. Diabetes 39 (1990) 1017-1027
36. Simsolo R.B., Ong J.M., Saffari B., et al. Effect of improved diabetes control on the expression of lipoprotein lipase in human adipose tissue. J Lipid Res 33 (1992) 89-95
37. Geltner C., Lechleitner M., Foger B., et al. Insulin improves fasting and postprandial lipemia in type 2 diabetes. Eur J Intern Med 13 (2002) 256-263
38. Pont F., Duvillard L., Florentin E., et al. Early kinetic abnormalities of apoB-containing lipoproteins in insulin-resistant women with abdominal obesity. Arterioscler Thromb Vasc Biol 22 (2002) 1726-1732
39. Cowie C.C., Howard B.V., and Harris M.I. Serum lipoproteins in African Americans and Whites with non-insulin-dependent diabetes in the US population. Circulation 90 (1994) 1185-1193
40. Pang R.W., Tam S., Janus E.D., et al. Plasma lipid, lipoprotein and apolipoprotein levels in a random population sample of 2875 Hong Kong Chinese adults and their implications (NCEP ATP-III, 2001 guidelines) on cardiovascular risk assessment. Atherosclerosis 184 (2006) 438-445
41. Howard B.V., Egusa G., Beltz W.F., et al. Compensatory mechanisms governing the concentration of plasma low density lipoprotein. J Lipid Res 27 (1986) 11-20
42. Chan D.C., Watts G.F., Redgrave T.G., et al. Apolipoprotein B-100 kinetics in visceral obesity: associations with plasma apolipoprotein C-III concentration. Metabolism 51 (2002) 1041-1046