Pattern recognition receptors and interleukin-8 mediate effects of Gram-positive and Gram-negative bacteria on lung epithelial cell function

British Journal of Pharmacology

Volumn 154, Issue 4, 2008, Pages 864-871

  Sorrentino, R ^a   De Souza, P M ^a   Sriskandan, S ^b   Duffin, C ^a   Paul Clark, M J ^a   Mitchell, J A ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Gram negative bacteria; Gram positive bacteria; Interleukin 8 (CXCL8); Nucleotide binding oligomerization domain (NODs) proteins; Toll like receptors (TLRs)

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 4; HEPTANOYL GAMMA DEXTRO GLUTAMYL 2,6 DIAMINOPIMELOYL DEXTRO ALANINE; INTERLEUKIN 8; PATTERN RECOGNITION RECEPTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ESCHERICHIA COLI; GENE EXPRESSION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; MONOLAYER CULTURE; NUCLEOTIDE BINDING SITE; OLIGOMERIZATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; REAL TIME POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

CELL LINE, TUMOR; CELLS, CULTURED; EPITHELIAL CELLS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; INTERLEUKIN-8; LUNG; NOD1 SIGNALING ADAPTOR PROTEIN; RECEPTORS, PATTERN RECOGNITION; TOLL-LIKE RECEPTOR 4;

EID: 44949208352     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.139     Document Type: Article

References (20)

1. Ahmed K, van der Meide PH, Turk JL (1989). Effect of anticancer drugs on the release of interferon gamma in vitro. Cancer Immunol Immunother 30: 213-218.
2. Alexander SPH, Mathie A, Peters JA (2007). Guide to receptors and channels. Br J Pharmacol 150 (Suppl 1): S1-S168.
3. Armstrong L, Medford AR, Uppington KM, Robertson J, Witherden IR, Tetley TD et al. (2004). Expression of functional Toll-like receptor-2 and -4 on alveolar epithelial cells. Am J Respir Cell Mol Biol 3: 241-245.
4. Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, Ryffel B et al. (2007). Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo. Am J Respir Crit Care Med 175: 595-603.
5. Chance B, Maehly AC (1955). Assay of catalases and peroxidases. Methods in Enzymol 2: 764-775.
6. Chaput C, Boneca IG (2007). Peptidoglycan detection by mammals and flies. Microb Infect 9: 637-647.
7. Dobos KM, Spotts EA, Quinn FD, King CH (2000). Necrosis of lung epithelial cells during infection with Mycobacterium tuberculosis is preceded by cell permeation. Infect Immun 68: 6300-6310.
8. Duffin C, Paul-Clark M, McMaster S, Sriskandan S, Mitchell JA (2005). Differential effects of Gram negative versus Gram positive bacteria on IL-8 release by human lung epithelial cells: role of Toll like receptors 2 and 4. Br J Pharmacol 3(2): abstract number 160P.
9. Edwards RJ, Taylor GW, Ferguson M, Murray S, Rendell N, Wrigley A et al. (2005). Specific C-terminal cleavage and inactivation of interleukin-8 by invasive disease isolates of Streptococcus pyogenes. J Infect Dis 192: 783-790.
10. Fritz JH, Ferrero RL, Philpott DJ, Girardin SE (2006). Nod-like proteins in immunity, inflammation and disease. Nat Immuno 7: 1250-1257.
11. Greene CM, Carroll TP, Smith SG, Taggart CC, Devaney J, Griffin S et al. (2005). TLR-induced inflammation in cystic fibrosis and noncystic fibrosis airway epithelial cells. J Immunol 174: 1638-1646.
12. Hoebe K, Georgel P, Rutschmann S, Du X, Mudd S, Crozat K et al. (2005). CD36 is a sensor of diacylglycerides. Nature 433: 523-527.
13. Jimenez R, Belcher E, Sriskandan S, Lucas R, McMaster SK, Vojonovic I et al. (2005). Role of Toll-like receptors 2 and 4 in the induction of cyclooxygenase-2 in vascular smooth muscle. Proc Natl Acad Sci USA 102: 4637-4642.
14. Mayer AK, Muehmer M, Mages J, Gueinzius K, Hess C, Heeg K et al. (2007). Differential recognition of TLR-dependent microbial ligands in human bronchial epithelial cells. J Immunol 178: 3134-3142.
15. Mitchell JA, Paul-Clark MJ, Clarke GW, McMaster SK, Cartwright N (2007). Critical role of Toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease. J Endocrinol 193: 323-330.
16. Paul-Clark MJ, McMaster SK, Belcher E, Sorrentino R, Anandarajah J, Fleet M et al. (2006). Differential effects of Gram-positive versus Gram-negative bacteria on NOSII and TNFalpha in macrophages: role of TLRs in synergy between the two. Br J Pharmacol 148: 1067-1075.
17. Platz J, Beisswenger C, Dalpke A, Koczulla R, Pinkenburg O, Vogelmeier C et al. (2004). Microbial DNA induces a host defense reaction of human respiratory epithelial cells. J Immunol 173: 1219-1223.
18. Schroder K, Sweet MJ, Hume DA (2006). Signal integration between IFNgamma and TLR signalling pathways in macrophages. Immunobiology 211: 511-524.
19. Stanford SJ, Pepper JR, Mitchell JA (2000). Cyclooxygenase-2 regulates granulocyte-macrophage colony-stimulating factor, but not interleukin-8, production by human vascular cells: role of cAMP. Arterioscler Thromb Vasc Biol 20: 677-682.
20. Talavera D, Castrilllo AM, Dominguez MC, Gutierrez AE, Meza I (2004). IL8 release, tight junction and cytoskeleton dynamic reorganization conducive to permeability increase are induced by dengue virus infection of microvascular endothelial monolayers. J Gen Virol 85: 1801-1813.