Transcriptional regulation of an evolutionary conserved intergenic region of CDT2-INTS7

PLoS ONE

Volumn 3, Issue 1, 2008, Pages

  Nakagawa, Hiroki ^a   Tategu, Moe ^a   Yamauchi, Rieko ^a   Sasaki, Kaori ^a   Sekimachi, Sota ^a   Yoshida, Kenichi ^a  

^a MEIJI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; GENE PRODUCT; INTEGRATOR COMPLEX SUBUNIT 7; LUCIFERASE; MESSENGER RNA; PROTEIN B MYB; PROTEIN C MYB; PROTEIN CDT2; PROTEIN P53; RNA POLYMERASE II; SPACER DNA; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F2; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTION FACTOR E2F4; TRANSCRIPTION FACTOR E2F5; TRANSCRIPTION FACTOR E2F6; DTL PROTEIN, HUMAN; NUCLEAR PROTEIN; PRIMER DNA; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; BASE PAIRING; CONTROLLED STUDY; DNA REPLICATION; DNA SEQUENCE; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TRANSFER; GENETIC CONSERVATION; GENETIC IDENTIFICATION; GENOME ANALYSIS; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MOLECULAR EVOLUTION; PHYSIOLOGY; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

MAMMALIA; RATTUS;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; HUMANS; MICE; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 44949204621     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001484     Document Type: Article

References (20)

1. Yoshida SH, Al-Amodi H, Nakamura T, McInerny CJ, Shimoda C (2003) The Schizosaccharomyces pombe cdt2(+) gene, a target of G1-S phase-specific transcription factor complex DSC1, is required for mitotic and premeiotic DNA replication. Genetics 164: 881-893.
2. Liu, C., Poitelea M, Watson A, Yoshida SH, Shimoda C, et al. (2005) Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase. EMBO J 24: 3940-3951.
3. Jin J, Arias EE, Chen J, Harper JW, Walter JC (2006) A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol Cell 23: 709-721.
4. Higa LA, Banks D, Wu M, Kobayashi R, Sun H, et al. (2006) L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage. Cell Cycle 5: 1675-1680.
5. Banks D, Wu M, Higa LA, Gavrilova N, Quan J, et al. (2006) L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes. Cell Cycle 5: 1719-1729.
6. Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, et al. (2005) Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II. Cell 123: 265-276.
7. Trinklein ND, Aldred SF, Hartman SJ, Schroeder DI, Otillar RP, et al. (2004) An abundance of bidirectional promoters in the human genome. Genome Res 14: 62-66.
8. Li YY, Yu H, Guo ZM, Guo TQ, Tu K, et al. (2006) Systematic analysis of head-to-head gene organization: evolutionary conservation and potential biological relevance. PLoS Comput Biol 2, Available: http://compbiol.plosjournals.org/perlserv/requestget-documentdoi=10.1371/ journal.pcbi.0020074.txt. Accessed 2006 Jul 7.
9. Bellizzi D, Dato S, Cavaleante P, Covello G, Di Cianni F, et al. (2007) Characterization of a bidirectional promoter shared between two human genes related to aging SIRT3 and PSMD13. Genomics 89: 143-150.
10. Chen PY, Chang WS, Chou RH, Lai YK, Lin SC, et al. (2007) Two non-homologous brain diseases-related genes, SERPINI1 and PDCD10, are tightly linked by an asymmetric bidirectional promoter in an evolutionarily conserved manner. BMC Mol Biol 8, Available: http://www.biomedcentral.com/1471-2199/8/2. Accessed 2007 Jan 9.
11. Gavalas A, Zalkin H (1995) Analysis of the chicken GPAT/AIRC bidirectional promoter for de novo purine nucleotide synthesis. J Biol Chem 270: 2403-2410.
12. Segal Y, Zhuang L, Rondeau E, Sraer JD, Zhou J (2001) Regulation of the paired type IV collagen genes COL4A5 and COL4A6. Role of the proximal promoter region. J Biol Chem (276): 11791-11797.
13. Sansam CL, Shepard JL, Lai K, Ianari A, Danielian PS, et al. (2006) DTL/ CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint. Genes Dev 20: 3117-3129.
14. Pan HW, Chou HY, Liu SH, Peng SY, Liu CL, et al. (2006) Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma. Cell Cycle 5: 2676-2687.
15. Johnson DG, Degregori J (2006) Putting the oncogenic and tumor suppressive activities of E2F into context. Curr. Mol Med 6: 731-738.
16. Yoshida K, Inoue I (2004) Regulation of Geminin and Cdt1 expression by E2F transcription factors. Oncogene 23: 3802-3812.
17. Hayashi R, Goto Y, Ikeda R, Yokoyama KK, Yoshida K (2006) CDCA4 is an E2F transcription factor family-induced nuclear factor that regulates E2F-dependent transcriptional activation and cell proliferation. J Biol Chem 281: 35633-35648.
18. Hayashi R, Goto Y, Tanaka R, Oonogi K, Hisasue M, et al. (2007) Transcriptional regulation of human chromatin assembly factor ASF1. DNA Cell Biol 26: 91-99.
19. Goto Y, Hayashi R, Kang D, Yoshida K (2006) Acute loss of transcription factor E2F1 induces mitochondrial biogenesis in HeLa cells. J Cell Physiol 209: 923-934.
20. Goto Y, Hayashi R, Muramatsu T, Ogawa H, Eguchi I, et al. (2006) JPO1/ CDCA7, a novel transcription factor E2F1-induced protein, possesses intrinsic transcriptional regulator activity. Biochim Biophys Acta 1759: 60-68.