Epigenetic disregulation induces cell growth retardation in primary cultured glial cells

Journal of Bioscience and Bioengineering

Volumn 105, Issue 5, 2008, Pages 470-475

  Nagai, Kaoru ^a   Natori, Takamitsu ^a   Nishino, Toru ^a   Kodaira, Fumiaki ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

brain development; DNA methylation; epigenetics; glia; histone deacetylation

Indexed keywords

ACETYLATION; ALKALI METALS; ALKYLATION; BIOTECHNOLOGY; CELLS; CHEMICAL MODIFICATION; CHROMATOGRAPHIC ANALYSIS; DNA; GENES; GROWTH KINETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LAWS AND LEGISLATION; LIQUID CHROMATOGRAPHY; LIQUID PHASE EPITAXY; MAMMALS; MATHEMATICAL MODELS; MECHANISMS; METHYLATION; NUCLEIC ACIDS; ORGANIC ACIDS; PAINTING; SODIUM; TECHNOLOGY;

C LEVEL; CELL CYCLING; CELL NUMBERS; CELLULAR TOXICITIES; DEACETYLATION (DD); DNA METHYLATION; EPIGENETIC MECHANISMS; GLIAL CELLS; GROWTH RETARDATION; HISTONE DEACETYLASE (HDAC) INHIBITORS; IN-VIVO; MTT ASSAYING; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP HPLC); S-PHASE; TRANSCRIPTIONAL CONTROL; TRANSCRIPTIONAL REGULATORY MECHANISMS; TRANSCRIPTIONAL REPRESSION; WEIGHT RATIOS;

CELL GROWTH;

5 AZA 2' DEOXYCYTIDINE; VALPROIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN DEVELOPMENT; BRAIN SIZE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL GROWTH; CONTROLLED STUDY; CYTOTOXICITY; DNA METHYLATION; EMBRYO; EPIGENETICS; GLIA CELL; GROWTH INHIBITION; MOUSE; NONHUMAN; TRANSCRIPTION REGULATION;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CEREBRAL CORTEX; EPIGENESIS, GENETIC; FEMALE; FETAL GROWTH RETARDATION; MICE; MICE, INBRED C57BL; NEUROGLIA; VALPROIC ACID;

RODENTIA;

EID: 44949142143     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.105.470     Document Type: Article

References (25)

1. Klose R.J., and Bird A. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31 (2006) 89-97
2. Baylin S.B. DNA methylation and gene silencing in cancer. Nat. Clin. Pract. Oncol. 2 (2005) S4-S11
3. Holmes R., and Soloway P.D. Regulation of imprinted DNA methylation. Cytogenet. Genome Res. 113 (2006) 122-129
4. Weaver I.C., Cervoni N., Champagne F.A., D'Alessio A.C., Sharma S., Seckl J.R., Dymov S., Szyf M., and Meaney M.J. Epigenetic programming by maternal behavior. Nat. Neurosci. 7 (2004) 847-854
5. Grayson D.R., Jia X., Chen Y., Sherma R.P., Mitchell C.P., Guidotti A., and Costa E. Reelin promoter hypermethylation in schizophrenia. Proc. Natl. Acad. Sci. USA 102 (2005) 9341-9346
6. Amir R.E., Van Den Veyver I.B., Wan M., Tran C.Q., Francke U., and Zoghbi H.Y. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 23 (1999) 185-188
7. Huppke P., and Gartner J. Molecular diagnosis of Rett syndrome. J. Child Neurol. 20 (2005) 732-736
8. Costa L.G., and Guizzetti M. Inhibition of muscarinic receptor-induced proliferation of astroglial cells by ethanol: mechanisms and implications for the fetal alcohol syndrome. Neurotoxicology 23 (2002) 685-691
9. Rajkowska G. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biol. Psychiatry 48 (2000) 766-777
10. Stark A.K., Uylings H.B.M., Sanz-Arigita E., and Pakkenberg B. Glial cell loss in the anterior cingulate cortex, a subregion of the prefrontal cortex, in subjects with schizophrenia. Am. J. Psychiatry 161 (2004) 882-888
11. Subramaniam B., Naidu S., and Reiss A.L. Neuroanatomy in Rett syndrome: cerebral cortex and posterior fossa. Neurology 48 (1997) 399-407
12. Nagai K., Miyake K., and Kubota T. A transcriptional repressor MeCP2 causing Rett syndrome is expressed in embryonic non-neuronal cells and controls their growth. Brain Res. Dev. Brain Res. 157 (2005) 103-106
13. Nagai K., Jiang M.H., Hada J., Nagata T., Yajima Y., Yamamoto S., and Nishizaki T. (-)-Epigallocatechin gallate protects against NO stress-induced neuronal damage after ischemia by acting as an anti-oxidant. Brain Res. 956 (2002) 319-322
14. Chang S.C., Tucker T., Thorogood N.P., and Brown C.J. Mechanisms of X-chromosome inactivation. Front. Biosci. 11 (2006) 852-866
15. Dragunow M., Greenwood J.M., Cameron R.E., Narayan P.J., O'carroll S.J., Pearson A.G., and Gibbons H.M. Valproic acid induces caspase 3-mediated apoptosis in microglial cells. Neuroscience 140 (2006) 1149-1156
16. Mitchell C.P., Chen Y., Kundakovic M., Costa E., and Grayson D.R. Histone deacetylase inhibitors decrease reelin promoter methylation in vitro. J. Neurochem. 93 (2005) 483-492
17. Brauch R.A., El-Masri M.A., Parker Jr. J.C., and El-Mallakh R.S. Glial cell number and neuron/glial cell ratios in postmortem brains of bipolar individuals. J. Affect. Disord. 91 (2006) 87-90
18. Wagner G.C., Reuhl K.R., Cheh M., Mcrae P., and Hallday A.K. A new neurobehavioral model of autism in mice: pre- and postnatal exposure to sodium valproate. J. Autism Dev. Disord. 36 (2006) 779-793
19. Redcay E., and Courchesne E. When is the brain enlarged in autism? A meta-analysis of all brain size reports. Biol. Psychiatry 58 (2005) 1-9
20. Shaw P., Greenstein D., Lerch J., Clasen L., Lenroot R., Gogtay N., Evans A., Rapoport J., and Giedd J. Intellectual ability and cortical development in children and adolescents. Nature 440 (2006) 676-679
21. Friso S., and Choi S.W. Gene-nutrient interactions in one-carbon metabolism. Curr. Drug Metab. 6 (2005) 37-46
22. Ulrey C.L., Liu L., Andrews L.G., and Tollefsbol T.O. The impact of metabolism on DNA methylation. Hum. Mol. Genet. 14 (2005) R139-R147
23. Moretti P., Peters S.U., del Gaudio D., Sahoo T., Hyland K., Bottiglieri T., Hopkin R.J., Peach E., Min S.H., Goldman D., et al. Brief report: autistic symptoms, developmental regression, mental retardation, epilepsy, and dyskinesias in CNS folate deficiency. J. Autism Dev. Disord. (November 20, 2007) 10.1007/s10803-007-0492-z (published online)
24. Clarke R., Birks J., Nexo E., Ueland P.M., Schneede J., Scott J., Molloy A., and Evans J.G. Low vitamin B-12 status and risk of cognitive decline in older adults. Am. J. Clin. Nutr. 86 (2007) 1384-1391
25. Gariballa S., and Forster S. Effects of dietary supplements on depressive symptoms in older patients: a randomized double-blind placebo-controlled trial. Clin. Nutr. 26 (2007) 545-551