Attenuation of maitotoxin-induced cytotoxicity in rat aortic smooth muscle cells by inhibitors of Na+/Ca2+ exchange, and calpain activation

Toxicon

Volumn 51, Issue 8, 2008, Pages 1400-1408

  Frew, Robert ^a   Wang, Yushan ^a   Weiss, Tracy M ^a   Nelson, Peggy ^a   Sawyer, Thomas W ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT CANADA   (Canada)

Author keywords

Ca2+ influx; Cell death; Cytotoxicity; Maitotoxin; Na+ Ca2+ exchange

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; [1 [(1 FORMYL 2 PHENYLETHYL)CARBAMOYL] 2 METHYLPROPYL]CARBAMIC ACID BENZYL ESTER; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALPAIN; ETHIDIUM BROMIDE; FURA 2; MAITOTOXIN; METHOTREXATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; EXTRACELLULAR CALCIUM; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER;

ANIMALS; CALCIUM; CALPAIN; CELLS, CULTURED; ENZYME ACTIVATION; ETHIDIUM; FLUORESCENT DYES; FLUOROMETRY; FURA-2; INDICATORS AND REAGENTS; ION TRANSPORT; MARINE TOXINS; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; OXAZINES; OXOCINS; RATS; SODIUM; SODIUM-CALCIUM EXCHANGER; THIOUREA; XANTHENES;

RATTUS;

EID: 44949099244     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.03.015     Document Type: Article

References (40)

1. Ashida T., and Blaustein M.P. Regulation of cell calcium and contractility in mammalian arterial smooth muscle: the role of the sodium-calcium exchange. J. Physiol. 392 (1987) 617-635
2. Araujo I.M., Carreira B.P., Pereira T., Santos P.F., Soulet D., Inacio A., Bahr B.A., Carvalho A.P., Ambrosio A.F., and Carvalho C.M. Changes in calcium dynamics following the reversal of the sodium-calcium exchanger have a key role in AMPA receptor mediated neurodegeneration via calpin activation in hippocampal neurons. Cell Death Different. 14 9 (2007) 1635-1646
3. 2+ exchanger in excitotoxicity. Cell 120 (2005) 275-285
4. 2+ exchanger is cleaved by distinct protease families in neuronal cell death. Ann. NY Acad. Sci. 1099 (2007) 451-455
5. Berta P., Phaneuf S., Derancourt J., Cassanova J., Durand-Clement M., le Peuch C., Haiech J., and Cavadore J.C. The effect of maitotoxin on phosphoinositides and calcium metabolism in a primary culture of aortic smooth muscle cells. Toxicon 26 (1988) 133-141
6. Blaustein M.P., Ambesi A., Bloch R.J., Goldman W.F., Juhaszova M., Lindenmayer G.E., and Weiss D.N. Regulation of vascular smooth muscle contractility: roles of the sarcoplasmic reticulum (SR) and the sodium/calcium exchanger. Jpn. J. Pharmacol. 58 Suppl. 2 (1992) 107P-114P
7. Choi O.H., Padgett W.L., Nishizawa Y., Gusovsky F., Yasumoto T., and Daly J.W. Maitotoxin effects on calcium channels, phosphoinositide breakdown, and arachidonic acid release in pheochromocytoma PC12 cells. Mol. Pharmacol. 37 (1990) 222-230
8. de la Rosa L.A., Parrilla A.-P., and Martinez-Martinez A. Biochemistry of maitotoxin. In: In: Botana L.M. (Ed). Phycotoxins Chemistry and Biochemistry (2007), Blackwell Publishing, Ames, IA 55-73
9. 2+ mobilization in ehrlich ascites tumor cells. Arch. Biochem. Biophys. 245 (1986) 84-95
10. Estacion M., Weinberg J.S., Sinkins W.G., and Schilling W.P. Blockade of maitotoxin-induced endothelial cell lysis by glycine and l-alanine. Am. J. Physiol. 284 (2003) C1006-C1020
11. Furchgott R.F. Spiral cut strips of rabbit aorta for in vitro studies of responses of arterial smooth muscle. Methods Med. Res. 8 (1960) 177-186
12. Gusovsky F., and Daley J.W. Maitotoxin: a unique pharmacological tool for research on calcium-dependent mechanisms. Biochem. Pharmacol. 39 (1990) 633-1639
13. Gusovsky F., Yasumoto ., and Daly J.W. Maitotoxin, a potent, general activator of phosphoinositide breakdown. FEBS Lett. 243 (1989) 307-312
14. Gutierrez D., Diaz de Leon L., and Vaca L. Characterization of the maitotoxin-induced influx pathway from human skin fibroblasts. Cell Calcium 22 (1997) 31-38
15. Hajimohammadreza I., Raser K.J., Nath R., Nadimpalli R., Scott E.W., and Wang K.K. Neuronal nitric oxide synthesis and calmodulin-dependent protein kinase II alpha undergo neurotoxin-induced proteolysis. J. Neurochem. 69 (1997) 1006-1013
16. 2+ exchange inhibitors. J. Pharmacol. Sci. 96 (2004) 27-32
17. 2+ exchange as a drug target-insight from molecular pharmacology and genetic engineering. Ann. NY Acad. Sci. 1099 (2007) 516-528
18. 2+ exchange in cells expressing NCX1. J. Biol. Chem. 271 (1996) 22391-22397
19. 2+ movements in guinea pig and rat cardiac muscles. Br. J. Pharmacol. 86 (1985) 385-391
20. 2+ exchange in spinal cord white matter injury at physiological temperatures. J. Neurophysiol. 84 (2000) 1116-1119
21. 7 receptor and the maitotoxin-activated cationic channel. Eur. J. Pharmacol. 487 (2004) 17-28
22. Morales-Tlalpan V., and Vaca L. Modulation of the maitotoxin response by intracellular and extracellular cations. Toxicon 40 (2002) 493-500
23. Morel N., and Godfraind T. Sodium/calcium exchange in smooth muscle microsomal fractions. Biochem. J. 218 (1984) 421-427
24. 2+ exchange in cultured vascular smooth muscle cells. Circ. Res. 62 (1988) 486-493
25. 2+ exchanger and tissue specific expression of isoforms. J. Biochem. 114 (1993) 528-534
26. Ohizumi Y., and Yasumoto T. Contractile response of the rabbit aorta to maitotoxin, the most potent marine toxin. J. Physiol. 327 (1983) 711-731
27. Sanders K.M. Signal transduction in smooth muscle invited review: mechanisms of calcium handling in smooth muscles. J. Appl. Physiol. 91 (2001) 1438-1449
28. Satoh E., Ishii T., and Niishimura M. The mechanism of maitotoxin-induced elevation of the cytosolic free calcium level in rat cerebrocortical synaptosomes. Jpn. J. Pharmacol. 85 (2001) 98-100
29. Sattler R., and Tymianski M. Molecular mechanisms of calcium-dependent excitotoxicity. J. Mol. Med. 78 (2000) 3-13
30. Sattler R., Charlton M.P., Hafner M., and Tymianski M. Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity. J. Neurochem. 71 (1998) 2349-2364
31. 7 purinergic receptor stimulation activates a common cytolytic pore. Am. J. Physiol. 277 (1999) C766-C776
32. Schilling W.P., Snyder D., Sinkins W.G., and Estacion M. Palytoxin-induced cell death cascade in bovine aortic endothelial cells. Am. J. Physiol. Cell Physiol. 291 (2006) 657-667
33. Soergel D.G., Yasumoto T., Daley J.W., and Gusovsky F. Maitotoxin effects are blocked by SK&F 96365, an inhibitor of receptor-mediated calcium entry. Mol. Pharmacol. 41 (1992) 487-493
34. 2+ channel activator candidate. J. Biol. Chem. 257 (1982) 7287-7289
35. 2+ channel activating function of maitotoxin, the most potent marine toxin known, in clonal rat pheochromocytoma cells. J. Biol. Chem. 258 (1983) 10944-10949
36. Wang K.K., Nath R., Raser K.J., and Hajimohammadreza I. Maitotoxin induces calpain activation in SH-SY5Y neuroblastoma cells and cerebrocortical cultures. Arch. Biochem. Biophys. 331 (1996) 208-214
37. Wisnoskey B.J., Estacion M., and Schilling W.P. Maitotoxin-induced cell death cascade in bovine aortic endothelial cells: divalent cation specificity and selectivity. Am. J. Physiol. Cell Physiol. 287 (2004) C345-C356
38. Yasumoto T. In: Botana L.M. (Ed). Historic Considerations Regarding Seafood Safety (2000) 1-17
39. 2+ in cultured human pulmonary artery smooth muscle cells. Am. J. Physiol. Cell Physiol. 228 (2005) C245-C252
40. Zhao X., Pike B.R., Newcombe J.K., Wang K.K.W., Postmantur R.M., and Hayes R.L. Maitotoxin induces calpain but not caspase-3 activation and necrotic cell death in primary septo-hippocampal cultures. Neurochem. Res. 24 (1999) 371-382