Angiogenesis and molecular markers as specific therapeutic targets in renal cell carcinomas

Analytical and Quantitative Cytology and Histology

Volumn 30, Issue 3, 2008, Pages 185-186

  Filosa, Alessandra ^a   Fabiani, Andrea ^b  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b Urology Operative Unit   (Italy)

Author keywords

Angiogenesis; Carcinoma, renal cell; Molecular markers

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BIOLOGICAL MARKER; CARBONATE DEHYDRATASE IX; GLUCOSE TRANSPORTER 1; PLATELET DERIVED GROWTH FACTOR B; TRANSFORMING GROWTH FACTOR ALPHA; VON HIPPEL LINDAU PROTEIN;

ANGIOGENESIS; CANCER GROWTH; CARCINOGENESIS; GENE EXPRESSION; HUMAN; KIDNEY CARCINOMA; LETTER; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANTINEOPLASTIC AGENTS; CARCINOMA, RENAL CELL; HUMANS; KIDNEY NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; TUMOR MARKERS, BIOLOGICAL;

EID: 44949083700     PISSN: 08846812     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (18)

1. Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990;82:4-6
2. Jubb AM, Pham TQ, Hanby AM, Frantz GD, Peale FV, Wu TD, Koeppen HW, Hillan KJ: Expression of vascular endothelial growth factor, hypoxia inducible factor 1alpha, and carbonic anhydrase IX in human tumours. J Clin Pathol 2004;57:504-512
3. Choi HJ, Choi IH, Cho NH, Choi HK: Color image analysis for quantifying renal tumor angiogenesis. Anal Quant Cytol Histol 2005;27:43-51
4. Kayser G, Radziszowski D, Bzdyl P, Sommer R, Kayser K: Theory and implementation of an electronic, automated measurement system for images obtained from immunohistochemically stained slides. Anal Quant Cytol Histol 2006;28:27-38
5. Tolivia J, Navarro A, del Valle E, Perez C, Ordoñez C, Martínez E: Application of Photoshop and Scion Image analysis to quantification of signals in histochemistry, immunocytochemistry and hybridocytochemistry. Anal Quant Cytol Histol 2006;28:43-53
6. Markiewicz T, Osowski S, Patera J, Kozlowski W: Image processing for accurate cell recognition and count on histologic slides. Anal Quant Cytol Histol 2006;28:281-291
7. Döme B, Hendrix MJ, Paku S, Tóvári J, Tímár J: Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications. Am J Pathol 2007;170:1-15
8. Bartels PH, Ranger-Moore J, Alberts D, Hess L, Scarpelli M, Montironi R: Carcinogenesis and the hypothesis of phylogenetic reversion. Anal Quant Cytol Histol 2006;28:243-252
9. Fox SB: Tumour angiogenesis and prognosis. Histopathology 1997;30:294-301
10. Takahashi A, Sasaki H, Kim SJ, Tobisu K, Kakizoe T, Tsukamoto T, Kumamoto Y, Sugimura T, Terada M: Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis. Cancer Res 1994;54:4233-4237
11. Reuter CW, Morgan MA, Grunwald V, Herrmann TR, Burchardt M, Ganser A: Targeting vascular endothelial growth factor (VEGF)-receptor-signaling in renal cell carcinoma. World J Urol 2007;25:59-72
12. Martignoni G, Brunelli M, Gobbo S, Remo A, Ficarra V, Cossu-Rocca P, Pea M, Chilosi M, Menestrina F, Cheng L: Role of molecular markers in diagnosis and prognosis of renal cell carcinoma. Anal Quant Cytol Histol 2007;29:41-49
13. Shuin T, Kondo K, Torigoe S, Kishida T, Kuboti Y, Hosaka M, Nagashima Y, Kitamura H, Latif F, Zbar B, et al: Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas. Cancer Res 1994;54:2852-2855
14. Herman JG, Latif F, Weng Y, Lerman MI, Zbar B, Liu S, Samid D, Duan DS, Gnarra JR, Linehan WM, et al: Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci U S A 1994;91:9700-9704
15. Kaelin WG Jr: The von Hippel-Lindau tumor suppressor gene and kidney cancer. Clin Cancer Res 2004;10:6290S-6295S
16. Brugarolas J: Renal-cell carcinoma - Molecular pathways and therapies. N Engl J Med 2007;356:185-187
17. Lopez-Beltran A, Maclennan GT, de la Haba- Rodriguez J, Montironi R, Cheng L: Research advances in apoptosis-mediated cancer therapy: A review. Anal Quant Cytol Histol 2007;29:71-78
18. Pospihalj B, Zamparese R, Mazzucchelli R, Morichetti D: Kidney cancer: Not a single disease. Anal Quant Cytol Histol 2007;29:377-379