A new method for producing urinary bladder hyperactivity using a non-invasive transient intravesical infusion of acetic acid in conscious rats

Journal of Pharmacological and Toxicological Methods

Volumn 57, Issue 3, 2008, Pages 188-193

  Mitobe, Manabu ^a   Inoue, Hirotaka ^a   Westfall, Timothy D ^b   Higashiyama, Hiroyuki ^a   Mizuyachi, Kaori ^a   Kushida, Hiroshi ^a   Kinoshita, Mine ^a  

^a Tsukuba Research Laboratories   (Japan)

^b Development and Medical Affairs Division   (Japan)

Author keywords

Acetic acid; Cystitis; Hyperactive bladder; Overactive bladder; Oxybutynin; Rat

Indexed keywords

ACETIC ACID; ISOFLURANE; OXYBUTYNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER DISEASE; CONSCIOUSNESS; CONTROLLED STUDY; DRUG EFFECT; FEMALE; MICTURITION; NONHUMAN; OVERACTIVE BLADDER; RAT; TOXICOKINETICS; URINE VOLUME;

ACETIC ACID; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MANDELIC ACIDS; MUSCARINIC ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; TIME FACTORS; URINARY BLADDER; URINARY BLADDER, OVERACTIVE; URINATION; URODYNAMICS;

ANIMALIA; RATTUS;

EID: 44649194476     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2007.12.001     Document Type: Article

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