Candida albicans HSP12 is co-regulated by physiological CO2 and pH

Fungal Genetics and Biology

Volumn 45, Issue 7, 2008, Pages 1075-1080

  Sheth, Chirag C ^a   Mogensen, Estelle G ^a   Fu, Man Shun ^a   Blomfield, Ian C ^a   Mühlschlegel, Fritz A ^a  

^a UNIVERSITY OF KENT   (United Kingdom)

Author keywords

Candida albicans; CO2; EMSA; HSP12; Microarray; pH; Transcriptional regulation

Indexed keywords

CARBON DIOXIDE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 12; TRANSCRIPTOME;

ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; MICROARRAY ANALYSIS; NONHUMAN; NORTHERN BLOTTING; PH; PRIORITY JOURNAL; RNA HYBRIDIZATION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

CANDIDA ALBICANS; CARBON DIOXIDE; CYCLIC AMP; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; HEAT-SHOCK PROTEINS; HYDROGEN-ION CONCENTRATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS;

CANDIDA ALBICANS;

EID: 44649168179     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2008.04.004     Document Type: Article

References (27)

1. Baek Y.U., Martin S.J., and Davis D.A. Evidence for novel pH-dependent regulation of Candida albicans Rim101, a direct transcriptional repressor of the cell wall beta-glycosidase Phr2. Eukaryot. Cell 5 (2006) 1550-1559
2. 2 sensing in fungi and beyond. Curr. Opin. Microbiol. 9 (2006) 572-578
3. El Barkani A., Kurzai O., Fonzi W.A., Ramon A., Porta A., Frosch M., and Mühlschlegel F.A.M. Dominant active alleles of RIM101 (PRR2) bypass the pH restriction on filamentation of Candida albicans. Mol. Cell. Biol. 20 (2000) 4635-4647
4. Barwell K.J., Boysen J.H., Xu W., and Mitchell A.P. Relationship of DFG16 to the Rim101p pH response pathway in Saccharomyces cerevisiae and Candida albicans. Eukaryot. Cell 4 (2005) 890-899
5. Berman J., and Sudbery P. Candida albicans: a molecular revolution built on lessons from budding yeast. Nat. Genet. 3 (2002) 918-930
6. Brown A.J.P., and Gow N.A.R. Regulatory networks controlling Candida albicans morphogenesis. Trends Microbiol. 7 (1999) 333-338
7. Brown D.H., Giusani A.D., Chen X., and Kumamoto C.A. Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene. Mol. Microbiol. 34 (1999) 651-662
8. Davis D. Adaptation to environmental pH in Candida albicans and its relation to pathogenesis. Curr. Genet. 44 (2003) 1-7
9. Davis D., Wilson B., and Mitchell A.P. RIM101-dependent and -independent pathways govern pH responses in Candida albicans. Mol. Cell. Biol. 20 (2000) 971-978
10. Davis D., Edwards J.E., Mitchell A.P., and Ibrahim A.S. Candida albicans RIM101 pH response pathway is required for host-pathogen interactions. Infect. Immun. 68 (2000) 5953-5959
11. De Bernardis F., Mühlschlegel F.A., Cassone A., and Fonzi W.A. The pH of the host niche controls gene expression in and virulence of Candida albicans. Infect. Immun. 66 (1998) 3317-3325
12. Eckert, S.E., Sheth, C.C., Mühlschlegel, F.A., 2007. Regulation of morphogenesis in Candida species. In: Hube, B., d'Enfert, C. (Eds.), Candida: Comparative and Functional Genomics, Horizon Scientific Press, Wymondham, ISBN: 978-1-904455-13-4 (Chapter 12).
13. Enjalbert B., Smith D.A., Cornell M.J., Alam I., Nicholls S., Brown A.J.P., and Quinn J. Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans. Mol. Biol. Cell 17 (2006) 1018-1032
14. Gasch A.P., Spellman P.T., Kao C.M., Carmel-Harel O., Eisen M.B., Storz G., Botstein G., and Brown P.O. Genomic expression programs in the response of yeast cells to environmental changes. Mol. Biol. Cell 11 (2000) 4241-4257
15. Kadosh D., and Johnson A.D. Induction of the Candida albicans filamentous growth program by relief of transcriptional repression: a genome-wide analysis. Mol. Biol. Cell 16 (2005) 2903-2912
16. Karababa M., Coste A.T., Rognon B., Bille J., and Sanglard D. Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters. Antimicrob. Agents Chemother. 48 (2004) 3064-3079
17. 2 sensing with cAMP signaling and virulence. Curr. Biol. 15 (2005) 2021-2026
18. Lamb T.M., Xu W., Diamond A., and Mitchell A.P. Alkaline response genes of Saccharomyces cerevisiae and their relationship to the RIM101 pathway. J. Biol. Chem. 276 (2001) 1850-1856
19. Lo H.-J., Kohler J.R., DiDomenico B., Loebenberg D., Cacciapuoti A., and Fink G.R. Nonfilamentous Candida albicans mutants are avirulent. Cell 90 (1997) 939-949
20. Mühlschlegel F.A., and Fonzi W.A. PHR2 of Candida albicans encodes a functional homolog of the pH-regulated gene PHR1 with an inverted pattern of pH-dependent expression. Mol. Cell. Biol. 17 (1997) 5960-5967
21. Nicholls S., Straffon M., Enjalbert B., Nantel A., Macaskill S., Whiteway M., and Brown A.J.P. Msn2- and Msn4-like transcription factors play no obvious roles in the stress responses of the fungal pathogen Candida albicans. Eukaryot. Cell 3 (2004) 1111-1123
22. Niimi M., Niimi K., Tokunaga J., and Nakayama H. Changes in cyclic nucleotide levels and dimorphic transition in Candida albicans. J. Bacteriol. 142 (1980) 1010-1014
23. Ramon A.M., and Fonzi W.A. Diverged binding specificity of Rim101p, the Candida albicans ortholog of PacC. Eukaryot. Cell 2 (2003) 718-728
24. Ramon A.M., Porta A., and Fonzi W.A. Effect of environmental pH on morphological development of Candida albicans is mediated via the PacC-related transcription factor encoded by PRR2. J. Bacteriol. 181 (1999) 7524-7530
25. Rocha C.R.C., Schroppel K., Harcus D., Marcil A., Dignard D., Taylor B.N., Thomas D.Y., Whiteway M., and Leberer E. Signaling through adenylyl cyclase is essential for hyphal growth and virulence in the pathogenic fungus Candida albicans. Mol. Biol. Cell 12 (2001) 3631-3643
26. Sheth C.C., Johnson E., Baker M.E., Haynes K., and Mühlschlegel F.A. Phenotypic identification of Candida albicans by growth on chocolate agar. Med. Mycol. 43 (2005) 735-738
27. Zara S., Farris G.A., Budroni M., and Bakalinsky A.T. HSP12 is essential for biofilm formation by a Sardinian wine strain of Saccharomyces cerevisiae. Yeast 19 (2002) 269-276