Cyclothiazide binding to the GABAA receptor

Neuroscience Letters

Volumn 439, Issue 1, 2008, Pages 66-69

  Szárics, Éva ^a   Simon, Ágnes ^a   Visy, Júlia ^a   Simon Trompler, Edit ^a   Banka, Zoltán ^a   Héja, László ^a   Hársing, László Gábor ^b   Blaskó, Gábor ^c   Kardos, Julianna ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

^b EGIS PHARMACEUTICALS LTD   (Hungary)

^c Servier Research Institute of Medicinal Chemistry   (Hungary)

Author keywords

( ) 1S,9R Bicuculline methiodide; 3H Cyclothiazide; 3H Flunitrazepam; 3H GABA; Binding in rat brain synaptic membrane; Diastereomeric fractions

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; BICUCULLINE METHIODIDE; CYCLOTHIAZIDE; DIAZEPAM; FLUNITRAZEPAM; PENTOBARBITAL; PICROTOXIN; 4 AMINOBUTYRIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; BENZOTHIADIAZINE DERIVATIVE; TRITIUM;

ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN CORTEX; DRUG PROTEIN BINDING; HIPPOCAMPUS; IC 50; MALE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; STATISTICAL SIGNIFICANCE; SYNAPTIC MEMBRANE; ANIMAL; BRAIN; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; METABOLISM; NERVE CELL; PROTEIN BINDING; SYNAPTOSOME; ULTRASTRUCTURE; WISTAR RAT;

ANIMALS; BENZOTHIADIAZINES; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; MALE; NEURONS; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, GABA-A; SYNAPTOSOMES; TRITIUM;

EID: 44649130009     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.04.092     Document Type: Article

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