Assessment of Silent Liver Fibrosis in Hemochromatosis C282Y Homozygotes With Normal Transaminase Levels

Clinical Gastroenterology and Hepatology

Volumn 6, Issue 6, 2008, Pages 713-714

  Beaton, Melanie ^a   Adams, Paul C ^a  

^a LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FERRITIN; IRON;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; FEMALE; HEMOCHROMATOSIS; HOMOZYGOTE; HUMAN; HUMAN TISSUE; IRON OVERLOAD; LIVER BIOPSY; LIVER DYSFUNCTION; LIVER FIBROSIS; LIVER INJURY; LIVER LEVEL; MAJOR CLINICAL STUDY; MALE; PATIENT REFERRAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BIOPSY; FEMALE; FERRITINS; HEMOCHROMATOSIS; HOMOZYGOTE; HUMANS; IRON; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PREVALENCE;

EID: 44649127419     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2008.02.024     Document Type: Article

References (13)

1. Alberti A., Benvegnu L., Boccato S., et al. Natural history of initially mild chronic hepatitis C. Dig Liver Dis 36 (2004) 646-654
2. Maida I., Soriano V., Barreiro P., et al. Liver fibrosis stage and HCV genotype distribution in HIV-HCV coinfected patients with persistently normal transaminases. AIDS Res Hum Retroviruses 23 (2007) 801-804
3. Sanchez-Conde M., Berenguer J., Miralles P., et al. Liver biopsy findings for HIV-infected patients with chronic hepatitis C and persistently normal levels of alanine aminotransferase. Clin Infect Dis 43 (2006) 640-644
4. Lai M., Hyatt B.J., Nasser I., et al. The clinical significance of persistently normal ALT in chronic hepatitis B infection. J Hepatol 47 (2007) 760-767
5. Mofrad P., Contos M.J., Haque M., et al. Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values. Hepatology 37 (2003) 1286-1292
6. Hourigan K.J., and Bowling F.G. Alcoholic liver disease: a clinical series in an Australian private practice. J Gastroenterol Hepatol 16 (2001) 1138-1143
7. Desmet V., Gerber M., Hoofnagle J., et al. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 19 (1994) 1513-1520
8. Adams P.C., and Chakrabarti S. Genotypic/phenotypic correlations in genetic hemochromatosis: evolution of diagnostic criteria. Gastroenterology 114 (1998) 319-323
9. Asberg A., Hveem K., Thorstensen K., et al. Screening for hemochromatosis-high prevalence and low morbidity in an unselected population of 65,238 persons. Scand J Gastroenterol 36 (2001) 1108-1115
10. Allen K.J., Gurrin L.C., Constantine C.C., et al. Iron-overload-related disease in HFE hereditary hemochromatosis. N Engl J Med 358 (2008) 221-230
11. Adams P.C., Passmore L., Chakrabarti S., et al. Liver diseases in the Hemochromatosis and Iron Overload Screening Study. Clin Gastroenterol Hepatol 4 (2006) 918-923
12. Bacon B.R., Olynyk J.K., Brunt E.M., et al. HFE genotype in patients with hemochromatosis and other liver diseases. Ann Intern Med 130 (1999) 953-962
13. Sorrentino P., Tarantino G., Conca P., et al. Silent non-alcoholic fatty liver disease-a clinical-histological study. J Hepatol 41 (2004) 751-757