Bone mineral density and body composition in prepubertal and adolescent patients with the classical form of 21-hydroxylase deficiency

Journal of the Medical Association of Thailand

Volumn 91, Issue 5, 2008, Pages 705-710

  Sahakitrungruang, Taninee ^a   Wacharasindhu, Suttipong ^a   Supornsilchai, Vichit ^a   Srivuthana, Sumarlee ^a   Kingpetch, Kanaungnit ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

21 hydroxylase deficiency; Body composition; Bone mineral density; Congenital adrenal hyperplasia

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; HYDROCORTISONE; HYDROXYPROGESTERONE; MINERALOCORTICOID; PRASTERONE SULFATE; PREDNISONE; STEROID 21 MONOOXYGENASE;

ADOLESCENT; ADULT; ARTICLE; AUTHOR; BODY COMPOSITION; BODY MASS; BONE DENSITY; BOY; CHILD; CLINICAL ARTICLE; CLINICAL EVALUATION; COMPARATIVE STUDY; CONGENITAL ADRENAL HYPERPLASIA; CONTROLLED STUDY; CORRELATION ANALYSIS; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; GIRL; HEIGHT; HORMONE BLOOD LEVEL; HUMAN; LONG TERM CARE; LUMBAR SPINE; MALE; OSTEOPENIA; PEDIATRICS; POPULATION; PREPUBERTY; SCORING SYSTEM; SEX; STATISTICAL SIGNIFICANCE; STEROID 21 MONOOXYGENASE DEFICIENCY; TREATMENT DURATION; WEIGHT;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; ADRENAL HYPERPLASIA, CONGENITAL; BODY COMPOSITION; BONE DENSITY; BONE DISEASES, METABOLIC; CASE-CONTROL STUDIES; CHILD; FEMALE; GLUCOCORTICOIDS; HUMANS; LUMBAR VERTEBRAE; MALE; OSTEOPOROSIS; SEXUAL MATURATION; STEROID 21-HYDROXYLASE; THAILAND;

EID: 44649123663     PISSN: 01252208     EISSN: 01252208     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Miller WL. Clinical review 54: Genetics, diagnosis, and management of 21-hydroxylase deficiency. J Clin Endocrinol Metab 1994; 78: 241-6.
2. Merke DP, Bornstein SR. Congenital adrenal hyperplasia. Lancet 2005; 365: 2125-36.
3. Merke DP, Bornstein SR, Avila NA, Chrousos GP. NIH conference. Future directions in the study and management of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Ann Intern Med 2002; 136: 320-34.
4. Raisz LG, Kream BE. Regulation of bone formation. N Engl J Med 1983; 309: 29-35.
5. Speiser PW, New MI, Gertner JM. Increased bone mineral density in congenital adrenal hyperplasia. Pediatr Res 1993; 33: S81 (Abstract 465)
6. Cameron FJ, Kaymakci B, Byrt EA, Ebeling PR, Warne GL, Wark JD. Bone mineral density and body composition in congenital adrenal hyperplasia. J Clin Endocrinol Metab 1995; 80: 2238-43.
7. Guo CY, Weetman AP, Eastell R. Bone turnover and bone mineral density in patients with congenital adrenal hyperplasia. Clin Endocrinol (Oxf) 1996; 45: 535-41.
8. Mora S, Saggion F, Russo G, Weber G, Bellini A, Prinster C, et al. Bone density in young patients with congenital adrenal hyperplasia. Bone 1996; 18: 337-40.
9. Gussinye M, Carrascosa A, Potau N, Enrubia M, Vicens-Calvet E, Ibanez L, et al. Bone mineral density in prepubertal and in adolescent and young adult patients with the salt-wasting form of congenital adrenal hyperplasia. Pediatrics 1997; 100: 671-4.
10. Paganini C, Radetti G, Livieri C, Braga V, Migliavacca D, Adami S. Height, bone mineral density and bone markers in congenital adrenal hyperplasia. Horm Res 2000; 54: 164-8.
11. Hagenfeldt K, Martin RE, Ringertz H, Helleday J, Carlstrom K. Bone mass and body composition of adult women with congenital virilizing 21-hydroxylase deficiency after glucocorticoid treatment since infancy. Eur J Endocrinol 2000; 143: 667-71.
12. Stikkelbroeck NM, Oyen WJ, van der Wilt GJ, Hermus AR, Otten BJ. Normal bone mineral density and lean body mass, but increased fat mass, in young adult patients with congenital adrenal hyperplasia. J Clin Endocrinol Metab 2003; 88: 1036-42.
13. King JA, Wisniewski AB, Bankowski BJ, Carson KA, Zacur HA, Migeon CJ. Long-term corticosteroid replacement and bone mineral density in adult women with classical congenital adrenal hyperplasia. J Clin Endocrinol Metab 2006; 91: 865-9.
14. Miller WL. The adrenal cortex. In: Rudolph AM, Hoffman JI, editors. Pediatrics. Norwalk, CT: Appleton & Lange; 1991: 1584-613.
15. Adler RA, Rosen CJ. Glucocorticoids and osteoporosis. Endocrinol Metab Clin North Am 1994; 23: 641-54.
16. Harris S, Dallal GE, Dawson-Hughes B. Influence of body weight on rates of change in bone density of the spine, hip, and radius in postmenopausal women. Calcif Tissue Int 1992; 50: 19-23.
17. Tremollieres FA, Pouilles JM, Ribot C. Vertebral postmenopausal bone loss is reduced in overweight women: a longitudinal study in 155 early postmenopausal women. J Clin Endocrinol Metab 1993; 77: 683-6.
18. Krall EA, Dawson-Hughes B. Heritable and lifestyle determinants of bone mineral density. J Bone Miner Res 1993; 8: 1-9.
19. Soyka LA, Fairfield WP, Klibanski A. Clinical review 117: Hormonal determinants and disorders of peak bone mass in children. J Clin Endocrinol Metab 2000; 85: 3951-63.
20. Wang MC, Aguirre M, Bhudhikanok GS, Kendall CG, Kirsch S, Marcus R, et al. Bone mass and hip axis length in healthy Asian, black, Hispanic, and white American youths. J Bone Miner Res 1997; 12: 1922-35.
21. Nelson DA, Simpson PM, Johnson CC, Barondess DA, Kleerekoper M. The accumulation of whole body skeletal mass in third- and fourth-grade children: effects of age, gender, ethnicity, and body composition. Bone 1997; 20: 73-8.