Transdermal oxygen does not improve sternal wound oxygenation in patients recovering from cardiac surgery

Anesthesia and Analgesia

Volumn 106, Issue 6, 2008, Pages 1619-1626

  Bakri, Mohamed H ^a   Nagem, Hassan ^a   Sessler, Daniel I ^a,d   Mahboobi, Ramatia ^a   Dalton, Jarrod ^b   Akça, Ozan ^c,d   Roselli, Eric E ^e   Insler, Steven R ^f  

^a Departments of Outcomes Research

^b Departments of Quantitative Health Sciences

^c Departments of Cardiothoracic Surgery

^d LERNER RESEARCH INSTITUTE   (United States)

^e University of Louisville School of Medicine   (United States)

^f Outcomes Research Consortium   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTERIAL OXYGEN TENSION; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; HEART SURGERY; HUMAN; INFECTION RISK; INSPIRATORY CAPACITY; INTENSIVE CARE UNIT; MALE; OXYGEN TISSUE LEVEL; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN SURFACE; STERNOTOMY; STERNUM; SURGICAL WOUND; TEMPERATURE MEASUREMENT; TISSUE OXYGENATION; TRANSDERMAL DRUG ADMINISTRATION; WOUND DRESSING; AERATION; AGED; BLOOD; DRUG EFFECT; INHALATIONAL DRUG ADMINISTRATION; INTRADERMAL DRUG ADMINISTRATION; METABOLISM; MIDDLE AGED; OCCLUSIVE DRESSING; PATHOPHYSIOLOGY; PILOT STUDY; SURGICAL INFECTION; TRANSCUTANEOUS OXYGEN MONITORING; TREATMENT OUTCOME; WOUND HEALING;

OXYGEN;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, INHALATION; AGED; BLOOD GAS MONITORING, TRANSCUTANEOUS; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; FEMALE; HUMANS; INSUFFLATION; MALE; MIDDLE AGED; OCCLUSIVE DRESSINGS; OXYGEN; PILOT PROJECTS; STERNUM; SURGICAL WOUND INFECTION; TREATMENT OUTCOME; WOUND HEALING;

EID: 44649119882     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e3181732e82     Document Type: Article

References (40)

1. Blanchard A, Hurni M, Ruchat P, Stumpe F, Fischer A, Sadeghi H. Incidence of deep and superficial sternal infection after open heart surgery. A ten-year retrospective study from 1981 to 1991. Eur J Cardiothorac Surg 1995;9:153-7
2. Cheung EH, Craver JM, Jones EL, Murphy DA, Hatcher CR Jr, Guyton RA. Mediastinitis after cardiac valve operations. Impact upon survival. J Thorac Cardiovasc Surg 1985;90:517-22
3. Farinas MC, Gald Peralta F, Bernal JM, Rabasa JM, Revuelta JM, Gonzalez-Macias J. Suppurative mediastinitis after open-heart surgery: a case-control study covering a seven-year period in Santander, Spain. Clin Infect Dis 1995;20:272-9
4. Vaska PL. Sternal wound infections. AACN Clin Issues Crit Care Nurs 1993;4:475-83
5. Tegnell A, Aren C, Ohman L. Coagulase-negative staphylococci and sternal infections after cardiac operation. Ann Thorac Surg 2000;69:1104-9
6. Babior BM. Oxygen-dependent microbial killing by phagocytes (first of two parts). N Engl J Med 1978;298:659-68
7. Niinikoski J, Jussila P, Vihersaari T. Radical mastectomy wound as a model for studies of human wound metabolism. Am J Surg 1973;126:53-8
8. Greif R, Akca O, Horn EP, Kurz A, Sessler DI. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. Outcomes Research Group. N Engl J Med 2000; 342:161-7
9. Hopf HW, Hunt TK, West JM, Blomquist P, Goodson WH III, Jensen JA, Jonsson K, Paty PB, Rabkin JM, Upton RA, von Smitten K, Whitney JD. Wound tissue oxygen tension predicts the risk of wound infection in surgical patients. Arch Surg 1997;132:997-1004; discussion 1005
10. Hutton JJ, Tappel AL, Udenfriend S. Cofactor and substrate requirements of collagen proline hydroxylase. Arch Biochem Biophys 1967;118:231-40
11. Myllyla R, Tuderman L, Kivirikko K. Mechanism of the prolyl hydroxylase reaction 2: Kinetic analysis of the reaction sequence. Eur J Biochem 1977;80:349-57
12. Gosain A, Rabkin J, Reymond JP, Jensen JA, Hunt TK, Upton RA. Tissue oxygen tension and other indicators of blood loss or organ perfusion during graded hemorrhage. Surgery 1991; 109:523-32
13. Shoemaker WC, Appel PL, Kram HB. Oxygen transport measurements to evaluate tissue perfusion and titrate therapy: dobutamine and dopamine effects. Crit Care Med 1991; 19:672-88
14. Ikeda T, Tayefeh F, Sessler DI, Kurz A, Plattner O, Petschnigg B, Hopf HW, West J. Local radiant heating increases subcutaneous oxygen tension. Am J Surg 1998;175:33-7
15. Plattner O, Akça O, Herbst F, Arkiliç CF, Fü gger R, Barlan M, Kurz A, Hopf H, Werba A, Sessler DI. The influence of two surgical bandage systems on wound tissue oxygen tension. Arch Surg 2000;135:818-22
16. Jensen JA, Goodson WH, Hopf HW, Hunt TK. Cigarette smoking decreases tissue oxygen. Arch Surg 1991;126:1131-4
17. Arkilic CF, Taguchi A, Sharma N, Ratnaraj J, Sessler DI, Read TE, Fleshman JW, Kurz A. Supplemental perioperative fluid administration increases tissue oxygen pressure. Surgery 2003;133:49-55
18. Akça O, Doufas AG, Morioka N, Iscoe S, Fisher J, Sessler DI. Hypercapnia improves tissue oxygenation. Anesthesiology 2002;97:801-6
19. Akça O, Liem E, Suleman MI, Doufas AG, Galandiuk S, Sessler DI. Effect of intra-operative end-tidal carbon dioxide partial pressure on tissue oxygenation. Anaesthesia 2003;58:536-42
20. Akca O, Melischek M, Scheck T, Hellwagner K, Arkilic CF, Kurz A, Kapral S, Heinz T, Lackner FX, Sessler DI. Postoperative pain and subcutaneous oxygen tension. Lancet 1999;354:41-2
21. Kurz A, Sessler DI, Lenhardt RA, Study of wound infections and temperature group. Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. N Engl J Med 1996;334:1209-15
22. Kabon B, Nagele A, Reddy D, Eagon C, Fleshman JW, Sessler DI, Kurz A. Obesity decreases perioperative tissue oxygenation. Anesthesiology 2004;100:274-80
23. Said HK, Hijjawi J, Roy N, Mogford J, Mustoe T. Transdermal sustained-delivery oxygen improves epithelial healing in a rabbit ear wound model. Arch Surg 2005;140:998-1004
24. Hunt TK, Rabkin J, Jensen JA, Jonsson K, von Smitten K, Goodson WH III. Tissue oximetry: an interim report. World J Surg 1987;11:126-32
25. Hopf HW, Hunt TK, Scheuenstuhl H, West JM, Humphrey LM, Rollins MD. Measuring oxygen in wounds. Methods Enzymol 2004;381:539-64
26. Sheffield CW, Sessler DI, Hopf HW, Schroeder M, Moayeri A, Hunt TK, West JM. Centrally and locally mediated thermoregulatory responses alter subcutaneous oxygen tension. Wound Rep Reg 1997;4:339-45
27. Treschan TA, Taguchi A, Ali SZ, Sharma N, Kabon B, Sessler DI, Kurz A. The effects of epidural and general anesthesia on tissue oxygenation. Anesth Analg 2003;96:1553-7
28. Kabon B, Fleischmann E, Treschan T, Taguchi A, Kapral S, Kurz A. Thoracic epidural anesthesia increases tissue oxygenation during major abdominal surgery. Anesth Analg 2003;97:1812-17
29. Ueno C, Hunt TK, Hopf HW. Using physiology to improve surgical wound outcomes. Plast Reconstr Surg 2006;117:59S-71S
30. Greif R, Akça O, Horn E-P, Kurz A, Sessler DI, Outcomes Research™ Group. Supplemental perioperative oxygen to reduce the incidence of surgical wound infection. N Engl J Med 2000;342:161-7
31. Hager H, Reddy D, Mandadi G, Pulley D, Eagon JC, Sessler DI, Kurz A. Hypercapnia improves tissue oxygenation in morbidly obese surgical patients. Anesth Analg 2006;103:677-81
32. Fleischmann E, Kurz A, Niedermayr M, Schebesta K, Kimberger O, Sessler DI, Kabon B, Prager G. Tissue oxygenation in obese and nonobese patients during laparoscopy. Obes Surg 2005; 15:813-19
33. Chang N, Goodson WH, Gottrup F, Hunt TK. Direct measurement of wound and tissue oxygen tension in postoperative patients. Ann Surg 1983;197:470-8
34. Fleischmann E, Herbst F, Kugener A, Kabon B, Niedermayr M, Sessler DI, Kurz A. Mild hypercapnia increases subcutaneous and colonic oxygen tension in patients given 80% inspired oxygen during abdominal surgery. Anesthesiology 2006; 104:944-9
35. Jensen JA, Goodson WH, Hopf HW, Hunt TK. Cigarette smoking decreases tissue oxygen. Arch Surg 1991;126:1131-4
36. Derbyshire DR, Smith G. Sympathoadrenal responses to anaesthesia and surgery. Br J Anaesth 1984;56:725-39
37. Halter JB, Pflug AE, Porte D Jr. Mechanism of plasma catecholamine increases during surgical stress in man. J Clin Endocrinol Metab 1977;45:936-44
38. Rabkin JM, Hunt TK. Local heat increases blood flow and oxygen tension in wounds. Arch Surg 1987;122:221-5
39. Sheffield CW, Sessler DI, Hopf HW, Schroeder M, Moayeri A, Hunt TK, West JM. Centrally and locally mediated thermoregulatory responses alter subcutaneous oxygen tension. Wound Repair Regen 1996;4:339-45
40. Allen DB, Maguire JJ, Mahdavian M, Wicke C, Marcocci L, Scheuenstuhl H, Chang M, Le AX, Hopf HW, Hunt TK. Wound hypoxia and acidosis limit neutrophil bacterial killing mechansims. Arch Surg 1997;132:991-6