A convenient synthesis and cytotoxic evaluation of N-unsubstituted α-methylene-γ-lactams

Tetrahedron

Volumn 64, Issue 27, 2008, Pages 6307-6314

  Krawczyk, Henryk ^a   Albrecht, Łukasz ^a   Wojciechowski, Jakub ^a   Wolf, Wojciech M ^a   Krajewska, Urszula ^b   Rózalski, Marek ^b  

^a LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Diethoxyphosphoryl lactams; Methylene lactams; Diastereoselective synthesis; Horner Wadsworth Emmons reaction

Indexed keywords

3 (DIETHOXYPHOSPHORYL) 4 (3,4 METHYLENEDIOXYPHENYL)PYRROLIDIN 2 ONE; 3 (DIETHOXYPHOSPHORYL) 4 (4 METHOXYPHENYL)PYRROLIDIN 2 ONE; 3 (DIETHOXYPHOSPHORYL) 4 (4 METHYLPHENYL)PYRROLIDIN 2 ONE; 3 (DIETHOXYPHOSPHORYL) 4 (METHOXYPHENYL) 5 METHYLPYRROLIDIN 2 ONE; 3 (DIETHOXYPHOSPHORYL) 5 METHYL 4 (3,4 METHYLENEDIOXYPHENYL)PYRROLIDIN 2 ONE; 3 (DIETHOXYPHOSPHORYL) 5 METHYL 4 (METHYLPHENYL)PYRROLIDIN 2 ONE; 3 ARYL 2 DIETHOXYPHOSPHORYL 4 NITROALKANOATE DERIVATIVE; 3 METHYLENE 4 (3,4 METHYLENEDIOXYPHENYL)PYRROLIDIN 2 ONE; 3 METHYLENE 4 (4 METHOXYPHENYL)PYRROLIDIN 2 ONE; 3 METHYLENE 4 (4 METHYLPHENYL)PYRROLIDIN 2 ONE; 4 (4 BROMOPHENYL) 3 (DIETHOXYPHOSPHORYL)PYRROLIDIN 2 ONE; 4 (4 BROMOPHENYL) 3 METHYLENEPYRROLIDIN 2 ONE; 4 (4 BROMOPHENYL) 5 METHYL 3 METHYLENE PYRROLIDIN 2 ONE; 4 (4 METHOXYPHENYL) 5 METHYL 3 METHYLENEPYRROLIDIN 2 ONE; 4 (BROMOPHENYL) 3 (DIETHOXYPHOSPHORYL) 5 METHYLPYRROLIDIN 2 ONE; 5 METHYL 3 METHYLENE 4 (3,4 METHYLENEDIOXYPHENYL)PYRROLIDIN 2 ONE; 5 METHYL 3 METHYLENE 4 (4 METHYLPHENYL)PYRROLIDIN 2 ONE; ALKANOIC ACID; ALPHA DIETHOXYPHOSPHORYL GAMMA LACTAM DERIVATIVE; CARBOPLATIN; LACTAM DERIVATIVE; N ALPHA METHYLENE GAMMA LACTAM DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REDUCTION; STEREOCHEMISTRY; SUBSTITUTION REACTION;

EID: 44649091928     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.04.090     Document Type: Article

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