Symptomatic hypercalcemia due to painless thyroiditis after unilateral adrenalectomy in a patient with cushing's syndrome

Internal Medicine

Volumn 47, Issue 8, 2008, Pages 751-756

  Kimura, Hironari ^a   Sato, Kanji ^a   Nishimaki, Momoko ^a   Miki, Nobuhiro ^a   Ono, Masami ^a   Takano, Kazue ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Addison's disease; Cushing's syndrome; Hypercalcemia; Hypoadrenalism; Painless thyroiditis; Thyrotoxicosis

Indexed keywords

ANTIHYPERTENSIVE AGENT; ATENOLOL; CALCIUM; HYDROCORTISONE;

ADRENAL CORTEX ADENOMA; ADRENALECTOMY; ADULT; ARTICLE; CALCIUM BLOOD LEVEL; CALCIUM EXCRETION; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CUSHING SYNDROME; DRUG DOSE REDUCTION; DRUG WITHDRAWAL; FEMALE; HUMAN; HYPERCALCEMIA; HYPERTENSION; OSTEOLYSIS; SYMPTOMATOLOGY; THYROIDITIS; THYROTOXICOSIS; URINARY EXCRETION; ADRENAL CORTEX TUMOR; METABOLISM; MIDDLE AGED; URINE;

ADRENAL CORTEX NEOPLASMS; ADRENALECTOMY; ADRENOCORTICAL ADENOMA; BONE RESORPTION; CALCIUM; CUSHING SYNDROME; FEMALE; HUMANS; HYPERCALCEMIA; MIDDLE AGED; THYROIDITIS;

EID: 44649089657     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.47.0616     Document Type: Article

References (34)

1. Sheppard MC, Gittoes NJ. The skeletal system in thyrotoxicosis. In: The Thyroid. 9th ed. Braverman LE, Utiger RD, Eds. Lippincott Williams and Wilkins, Philadelphia, 2005: 629-636.
2. Bringhurst FR, Demay MB, Kronenberg RM. Hormones and disorders of Mineral Metabolism. Williams Textbook of Endocrinology. 10th ed. Saunders, Philadelphia, 2003: 1303-1371.
3. Nerup, J. Addison's disease - clinical studies. A report of 108 cases. Acta Endocrinol (Copenh) 76: 127-141, 1974.
4. Takasu N, Komiya I, Nagasawa Y, Asawa T, Yamada T. Exacerbation of autoimmune thyroid dysfunction after unilateral adrenalectomy in patients with Cushing's syndrome due to an adrenocortical adenoma. N Engl J Med 322: 1708-1712, 1990.
5. Stewart PM. The adrenal cortex. In: Williams Textbook of Endocrinology. 10th. Larsen PR, Kronenberg HM, Melmed S, Polonsky KS, Eds. Saunders, Philadelphia, 2003: 491-551.
6. Cooper MS, Stewart PM. Corticosteroid insufficiency in acutely ill patients. N Engl J Med 348: 727-734, 2003.
7. Portale AA. Blood calcium, Phosphorus, and Magnesium. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 5th ed. Favus MJ, Ed. American Society for Bone and Mineral Research, Washington D.C., 2003: 151-154.
8. Baxter JD, Bondy PK. Hypercalcemia of thyrotoxicosis. Ann Intern Med 65: 429-442, 1966.
9. Burman KD, Monchik JM, Earll JM, Wartofsky L. Ionized and total serum calcium and parathyroid hormone in hyperthyroidism. Ann Intern Med 84: 668-671, 1976.
10. Kaye TB. Hypercalcemia due to subacute thyroiditis. Endocr Pract 3: 357-358, 1997.
11. Daly JG, Greenwood RM, Himsworth RL. Serum calcium concentration in hyperthyroidism at diagnosis and after treatment. Clin Endocrinol (Oxf) 19: 397-404, 1983.
12. Raisz LG, Kream BE, Lorenzo JA. Metabolic bone disease. In: Williams Textbook of Endocrinology. 10th ed. Wilson JD, Foster DW, Kronenberg HM, Larsen PR, Eds. Saunders, Philadelphia, 2003: 1373-1410.
13. Sato K, Han DC, Fujii Y, Tsushima T, Shizume K. Thyroid hormone stimulates alkaline phosphatase activity in cultured rat osteoblastic cells (ROS 17/2.8) through 3,5,3′-triiodo-L-thyronine nuclear receptors. Endocrinology 120: 1873-1881, 1987.
14. Abu EO, Bord S, Homer A, Chatteijee VK, Compston JE. The expression of thyroid hormone receptors in human bone. Bone 21: 137-142, 1997.
15. Mundy GR, Shapiro JL, Bandelin JG, Canalis EM, Raisz LG. Direct stimulation of bone resorption by thyroid hormones. J Clin Invest 58: 529-534, 1976.
16. Miura M, Tanaka K, Komatsu Y, et al. A novel interaction between thyroid hormones and 1,25 (OH) (2)D (3) in osteoclast formation. Biochem Biophys Res Commun 291: 987-994, 2002.
17. Kanatani M, Sugimoto T, Sowa H, Kobayashi T, Kanzawa M, Chihara K. Thyroid hormone stimulates osteoclast differentiation by a mechanism independent of RANKL-RANK interaction. J Cell Physiol 201: 17-25, 2004.
18. Pantazi H, Papapetrou PD. Changes in parameters of bone and mineral metabolism during therapy for hyperthyroidism. J Clin Endocrinol Metab 85: 1099-1106, 2000.
19. Walker DA, Davies M. Addison's disease presenting as a hypercalcemic crisis in a patient with idiopathic hypoparathyroidism. Clin Endocrinol (Oxf) 14: 419-423, 1981.
20. Miell J, Wassif W, McGregor A, Butler J, Ross R. Life-throatening hypercalcaemia in association with Addisonian crisis. Postgrad Med J 67: 770-772, 1991.
21. Canalis E. Mechanisms of glucocorticoid-induced osteoporosis. Curr Opin Rheumatol 15: 454-457, 2003.
22. Canalis E. Clinical review 83: Mechanisms of glucocorticoid action in bone: implications to glucocorticoid-induced osteoporosis. J Clin Endocrinol Metab 81: 3441-3447, 1996.
23. Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev 21: 115-137, 2000.
24. Richtsmeier AJ, Henry RA, Bloodworth JM Jr, Ehrlich EN. Lymphoid hypophysitis with selective adrenocorticotropic hormone deficiency. Arch Intern Med 140: 1243-1245, 1980.
25. Jensen MD, Handwerger BS, Scheithauer BW, Carpenter PC, Mirakian R, Banks PM. Lymphocytic hypophysitis with isolated corticotropin deficiency. Ann Intern Med 105: 200-203, 1986.
26. Casson IF, Walker BA, Hipkin LJ. Thyrotoxicosis in a patient with Addison's disease. Br J Clin Pract 44: 381-382, 1990.
27. Vasikaran SD, Tallis GA, Braund WJ. Secondary hypoadrenalism presenting with hypercalcaemia. Clin Endocrinol (Oxf) 41: 261-264, 1994.
28. Patel MC, Clayton RN. Secondary hypoadrenalism with hypercalcaemia. Clin Endocrinol (Oxf) 41: 839-840, 1994.
29. Strachan MW, Walker JD, Patrick AW Severe hypercalcemia secondary to isolated adrenocorticotrophic hormone deficiency and subacute thyroiditis. Ann Clin Biochem 40: 295-297, 2003.
30. Fujikawa M, Karnihim K, Sato K, Okamum K, Kidota S, Lida M. Elevated bone resorption markers in a patient with ~ypercalcemia associated with post-partum thyrotoxicosis and hypoadrenocorticism due to pituitary failure. J Endocrinol Invest 27: 782-787, 2004.
31. Hotta M, Sato K, Shibasaki T, Demum H. Hypercalcemia in an euthyroid patient with secondary hypoadrenalism and diabetes insipidus due to hypothalamic tumor. Endocr J 45: 773-778, 1998.
32. Muls E, Bouillon R, Boelaert J, et al. Etiology of hypercalcemia, in a patient with Addison's disease. Calcif Tissue Int 34: 523-526, 1982.
33. Eriksen EF, Mosekilde L, Melsen F. Trabecular bone remodeling and bone balance in hyperthyroidism. Bone 6: 421-428, 1985.
34. Yanagisawa T, Sato K, Kato Y, Shimizu S, Takano K. Rapid differential diagnosis of Graves' disease and painless thyroiditis using total T3/T4 ratio, TSH, and total alkaline phosphatase activity. Endocr J 52: 29-36, 2005.