Generation and characterization of recombinant feline β-galactosidase for preclinical enzyme replacement therapy studies in GM1 gangliosidosis

Metabolic Brain Disease

Volumn 23, Issue 2, 2008, Pages 161-173

  Samoylova, Tatiana I ^a   Martin, Douglas R ^a   Morrison, Nancy E ^a   Hwang, Misako ^a   Cochran, Anna M ^a   Samoylov, Alexandre M ^a   Baker, Henry J ^a   Cox, Nancy R ^a  

^a AUBURN UNIVERSITY   (United States)

Author keywords

galactosidase; Enzyme replacement therapy; GM1 gangliosidosis

Indexed keywords

AGAROSE; BETA GALACTOSIDASE; COMPLEMENTARY DNA;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CAT; CHO CELL; CHROMATOGRAPHY; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME PURIFICATION; ENZYME RELEASE; ENZYME REPLACEMENT; GENETIC TRANSFECTION; GM1 GANGLIOSIDOSIS; IMMUNOREACTIVITY; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN;

ANIMALS; ANTIBODY SPECIFICITY; BETA-GALACTOSIDASE; CATS; CHO CELLS; CHROMATOGRAPHY, AGAROSE; CLONING, MOLECULAR; CRICETINAE; CRICETULUS; CULTURE MEDIA, CONDITIONED; DISEASE MODELS, ANIMAL; DNA, COMPLEMENTARY; G(M1) GANGLIOSIDE; GANGLIOSIDOSIS, GM1; GENE THERAPY; GENETIC VECTORS; MOLECULAR WEIGHT; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA; CRICETULUS GRISEUS; FELIDAE; MAMMALIA;

EID: 44449176951     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-008-9086-5     Document Type: Article

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