Is propofol a safe alternative to pentobarbital for sedation during pediatric diagnostic CT?

Radiology

Volumn 247, Issue 2, 2008, Pages 528-534

  Zgleszewski, Steven E ^a   Zurakowski, David ^a   Fontaine, Paulette J ^a   D'Angelo, Margaret ^a   Mason, Keira P ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PENTOBARBITAL; PROPOFOL; HYPNOTIC SEDATIVE AGENT;

AIRWAY OBSTRUCTION; ARTICLE; CHILD; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CONVALESCENCE; DRUG SAFETY; FEMALE; HUMAN; INFORMED CONSENT; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SEDATION; CHI SQUARE DISTRIBUTION; COMPARATIVE STUDY; CONSCIOUS SEDATION; METHODOLOGY; NONPARAMETRIC TEST; PROSPECTIVE STUDY; STATISTICAL MODEL;

CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; CONSCIOUS SEDATION; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; LINEAR MODELS; MALE; PENTOBARBITAL; PROPOFOL; PROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC; TOMOGRAPHY, X-RAY COMPUTED;

EID: 44449146498     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.2472062087     Document Type: Article

References (27)

1. Karian VE, Burrows PE, Zurakowski D, Connor L, Poznauskis L, Park Mason K. The development of a pediatric radiology sedation program. Pediatr Radiol 2002;32:348-353.
2. Mason KP, Zurakowski D, Connor L, et al. Infant sedation for MR imaging and CT: oral versus intravenous pentobarbital. Radiology 2004;233:723-728.
3. American Society of Anesthesiologists Task Force on Sedation and Analgesia by Non-Anesthesiologists. Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology 2002;96:1004-1017.
4. Heuss LT, Schnieper P, Drewe J, Pflimlin E, Beglinger C. Risk stratification and safe administration of propofol by registered nurses supervised by the gastroenterologist: a prospective observational study of more than 2000 cases. Gastrointest Endosc 2003;57:664-671.
5. Heuss LT, Schnieper P, Drewe J, Pflimlin E, Beglinger C. Safety of propofol for conscious sedation during endoscopic procedures in high-risk patients: a prospective, controlled study. Am J Gastroenterol 2003;98:1751-1757.
6. Rex DK, Overley C, Kinser K, et al. Safety of propofol administered by registered nurses with gastroenterologist supervision in 2000 endoscopic cases. Am J Gastroenterol 2002;97:1159-1163.
7. Faigel DO, Baron TH, Goldstein JL, et al. Guidelines for the use of deep sedation and anesthesia for GI endoscopy. Gastrointest Endosc 2002;56:613-617.
8. Green SM, Krauss B. Propofol in emergency medicine: pushing the sedation frontier. Ann Emerg Med 2003;42:792-797.
9. Bassett KE, Anderson JL, Pribble CG, Guenther E. Propofol for procedural sedation in children in the emergency department. Ann Emerg Med 2003;42:773-782.
10. Guenther E, Pribble CG, Junkins EP Jr, Kadish HA, Bassett KE, Nelson DS. Propofol sedation by emergency physicians for elective pediatric outpatient procedures. Ann Emerg Med 2003;42:783-791.
11. Evans RG, Crawford MW, Noseworthy MD, Yoo SJ. Effect of increasing depth of propofol anesthesia on upper airway configuration in children. Anesthesiology 2003;99:596-602.
12. Pershad J, Wan J, Anghelescu DL. Comparison of propofol with pentobarbital/midazolam/fentanyl sedation for magnetic resonance imaging of the brain in children. Pediatrics 2007;120:e629-e636.
13. Usher AG, Kearney RA, Tsui BC. Propofol total intravenous anesthesia for MRI in children. Paediatr Anaesth 2005;15:23-28.
14. Mason KP, Sanborn P, Zurakowski D, et al. Superiority of pentobarbital versus chloral hydrate for sedation in infants during imaging. Radiology 2004;230:537-542.
15. American Academy of Pediatrics Committee on Drugs. Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures. Pediatrics 1992;89:1110-1115.
16. Committee on Drugs, Section on Anesthesiology. Guidelines for the elective use of conscious sedation, deep sedation, and general anesthesia in pediatric patients. Pediatrics 1985;76:317-321.
17. Newcombe RG. Two-sided confidence intervals for the single proportion: comparison of seven methods. Stat Med 1998;17:857-872.
18. Medina LS, Zurakowski D. Measurement variability and confidence intervals in medicine: why should radiologists care? Radiology 2003;226:297-301.
19. Rosner B. Hypothesis testing: categorical data. In: Fundamentals of biostatistics. 6th ed. Belmont, Calif: Duxbury, 2006; 393, 401.
20. Vittinghoff E, Glidden DV, Shiboski SC, McCulloch CE. Regression methods in biostatistics. New York, NY: Springer, 2005.
21. Chung T, Hoffer FA, Connor L, Zurakowski D, Burrows PE. The use of oral pentobarbital sodium (Nembutal) versus oral chloral hydrate in infants undergoing CT and MR imaging: a pilot study. Pediatr Radiol 2000;30:332-335.
22. Mason KP, Zurakowski D, Karian VE, Connor L, Fontaine PJ, Burrows PE. Sedatives used in pediatric imaging: comparison of IV pentobarbital with IV pentobarbital with midazolam added. AJR Am J Roentgenol 2001;177:427-430.
23. Sanborn PA, Michna E, Zurakowski D, et al. Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations. Radiology 2005;237:288-294.
24. Frankville DD, Spear RM, Dyck JB. The dose of propofol required to prevent children from moving during magnetic resonance imaging. Anesthesiology 1993;79:953-958.
25. Funk W, Taeger K. Anaesthesia for magnetic resonance imaging/computed tomography. Curr Opin Anaesthesiol 2000;13:429-432.
26. Reeves ST, Havidich JE, Tobin DP. Conscious sedation of children with propofol is anything but conscious. Pediatrics 2004;114:e74-76.
27. Powers KS, Nazarian EB, Tapyrik SA, et al. Bispectral index as a guide for titration of propofol during procedural sedation among children. Pediatrics 2005;115:1666-1674.