The TGF-β-induced gene product, βig-h3: Its biological implications in peritoneal dialysis

Nephrology Dialysis Transplantation

Volumn 23, Issue 1, 2008, Pages 126-135

  Park, Sun Hee ^a   Choi, Soon Youn ^a   Kim, Mi Hyung ^a   Oh, Eun Joo ^a   Ryu, Hye Myung ^a   Kim, Chan Duck ^a   Kim, In San ^a   Kim, Yong Lim ^a,b  

^a Kyungpook National University School of Medicine   (South Korea)

^b Kyungpook National University Hospital   (South Korea)

Author keywords

ig h3; Fibrosis; High glucose; Mesothelial cells; Peritoneum; TGF 1

Indexed keywords

FIBRONECTIN; GENE PRODUCT; MONOCLONAL ANTIBODY; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA1; VITRONECTIN RECEPTOR; BETAIG H3 PROTEIN; BETAIG-H3 PROTEIN; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL DAMAGE; CELL MEMBRANE; CONTROLLED STUDY; FIBROSIS; HUMAN; HUMAN CELL; MESOTHELIUM CELL; NONHUMAN; PERITONEAL DIALYSIS; PERITONEUM; PRIORITY JOURNAL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; EPITHELIUM CELL; METABOLISM; PHYSIOLOGY;

CELLS, CULTURED; EPITHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; HUMANS; PERITONEAL DIALYSIS; PERITONEUM; TRANSFORMING GROWTH FACTOR BETA;

EID: 44449096629     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfm540     Document Type: Article

References (23)

1. Gotloib L, Wajsbrot V, Shostak A, Khrizman V. Repopulation of the mesothelial monolayer during long-term experimental peritoneal dialysis. Contrib Nephrol 2006; 150: 54-61
2. Williams JD, Craig KJ, Topley N et al. Peritoneal Biopsy Study Group. Morphologic changes in the peritoneal membrane of patients with renal disease. J Am Soc Nephrol 2002; 13: 470-479
3. Williams JD, Craig KJ, von Ruhland C et al. The natural course of peritoneal membrane biology during peritoneal dialysis. Kidney Int Suppl 2003; 88: S43-S49
4. Kang DH, Hong YS, Lim HJ, Choi JH, Han DS, Yoon KI. High glucose solution and spent dialysate stimulate the synthesis of transforming growth factor-beta1 of human peritoneal mesothelial cells: effect of cytokine costimulation. Perit Dial Int 1999; 19: 221-230
5. Ha H, Lee HB. Effect of high glucose on peritoneal mesothelial cell biology. Perit Dial Int 2000; 20 [Suppl 2]: S15-S18
6. Mlambo NC, Hylander B, Brauner A. Increased levels of transforming growth factor beta 1 and basic fibroblast growth factor in patients on CAPD: a study during non-infected steady state and peritonitis. Inflammation 1999; 23: 131-139
7. Roberts AB. Molecular and cell biology of TGF-beta. Miner Electrolyte Metab 1998; 24: 111-119
8. Clark DA, Coker R. Transforming growth factor-beta (TGF-beta). Int J Biochem Cell Biol 1998; 30: 293-298
9. Gilbert RE, Wilkinson-Berka JL, Johnson DW et al. Renal expression of transforming growth factor-beta inducible gene-h3 (beta ig-h3) in normal and diabetic rats. Kidney Int 1998; 54: 1052-1062
10. Oh JE, Kook JK, Min BM. Beta ig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin alpha3beta1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. J Biol Chem 2005; 280: 21629-21637
11. Stylianou E, Jenner LA, Davies M, Coles GA, Williams JD. Isolation, culture and characterization of human peritoneal mesothelial cells. Kidney Int 1990; 37: 1563-1570
12. Park SW, Bae JS, Kim KS et al. Beta ig-h3 promotes renal proximal tubular epithelial cell adhesion, migration and proliferation through the interaction with alpha3beta1 integrin. Exp Mol Med 2004; 36: 211-219
13. Landegren U. Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens. J Immunol Methods 1984; 67: 379-388
14. Lee SH, Bae JS, Park SH et al. Expression of TGF-beta-induced matrix protein betaig-h3 is up-regulated in the diabetic rat kidney and human proximal tubular epithelial cells treated with high glucose. Kidney Int 2003; 64: 1012-1021
15. Park SH, Lee EG, Kim IS, Kim YJ, Cho DK, Kim YL. Effect of glucose degradation products on the peritoneal membrane in a chronic inflammatory infusion model of peritoneal dialysis in the rat. Perit Dial Int 2004; 24: 115-122
16. LeBaron RG, Bezverkov KI, Zimber MP, Pavelec R, Skonier J, Purchio AF. Beta IG-H3, a novel secretory protein inducible by transforming growth factor-beta, is present in normal skin and promotes the adhesion and spreading of dermal fibroblasts in vitro. J Invest Dermatol 1995; 104: 844-849
17. Bae JS, Lee SH, Kim JE et al. Betaig-h3 supports keratinocyte adhesion, migration, and proliferation through a3b1 integrin. Biochem Biophys Res Commun 2002; 294: 940-948
18. Skonier J, Bennett K, Rothwell V et al. betaig-h3: a transforming growth factor-beta-responsive gene encoding a secreted protein that inhibits cell attachment in vitro and suppresses the growth of CHO cells in nude mice. DNA Cell Biol 1994; 13: 571-584
19. Kim JE, Kim EH, Han EH et al. A TGF-beta-inducible cell adhesion molecule, betaig-h3, is downregulated in melorheostosis and involved in osteogenesis. J Cell Biochem 2000; 77: 169-178
20. Ha SW, Kim HJ, Bae JS et al. Elevation of urinary betaig-h3, transforming growth factor-beta-induced protein in patients with type 2 diabetes and nephropathy. Diabetes Res Clin Pract 2004; 65: 167-173
21. Zweers MM, de Waart DR, Smit W, Struijk DG, Krediet RT. Growth factors VEGF and TGF-beta1 in peritoneal dialysis. J Lab Clin Med 1999; 134: 124-132
22. Tietze L, Borntraeger J, Klosterhalfen B et al. Expression and function of beta(1) and beta(3) integrins of human mesothelial cells in vitro. Exp Mol Pathol 1999; 66: 131-139
23. Rout UK, Saed GM, Diamond MP. Transforming growth factor-beta1 modulates expression of adhesion and cytoskeletal proteins in human peritoneal fibroblasts. Fertil Steril 2002; 78: 154-161