메뉴 건너뛰기




Volumn 17, Issue 5, 2008, Pages 805-810

Vernakalant - A promising therapy for conversion of recent-onset atrial fibrillation

Author keywords

Antiarrhythmic agents; Atrial fibrillation; Vernakalant

Indexed keywords

AMIODARONE; ANTIARRHYTHMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CYTOCHROME P450; DIGOXIN; DOFETILIDE; IBUTILIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL; KYNAPID; PLACEBO; POTASSIUM CHANNEL KV1.5; QUINIDINE; SHAL POTASSIUM CHANNEL; SOTALOL; VERNAKALANT; VOLTAGE DEPENDENT ANION CHANNEL; ANISOLE DERIVATIVE; ION CHANNEL; PYRROLIDINE DERIVATIVE;

EID: 44449088060     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.17.5.805     Document Type: Review
Times cited : (21)

References (18)
  • 1
    • 0037456806 scopus 로고    scopus 로고
    • Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: Comparative efficacy and results of trials
    • Naccarelli GV, Wolbrette DL, Khan M, et al. Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials. Am J Cardiol 2003;91:15D-26D
    • (2003) Am J Cardiol , vol.91
    • Naccarelli, G.V.1    Wolbrette, D.L.2    Khan, M.3
  • 2
    • 34447334793 scopus 로고    scopus 로고
    • Percutaneous catheter ablation of atrial fibrillation
    • Daoud EG. Percutaneous catheter ablation of atrial fibrillation. Expert Rev Cardiovasc Ther 2007;59:693-705
    • (2007) Expert Rev Cardiovasc Ther , vol.59 , pp. 693-705
    • Daoud, E.G.1
  • 3
    • 3543072295 scopus 로고    scopus 로고
    • Antiarrhythmic drugs in atrial fibrillation: An overview of new agents, their mechanisms of action and potential clinical utility
    • Choudhury A. Lip GY. Antiarrhythmic drugs in atrial fibrillation: an overview of new agents, their mechanisms of action and potential clinical utility. Expert Opin Investig Drug 2004;13:841-55
    • (2004) Expert Opin Investig Drug , vol.13 , pp. 841-855
    • Choudhury, A.1    Lip, G.Y.2
  • 4
  • 5
    • 33644810948 scopus 로고    scopus 로고
    • The mechanism of atrial antiarrhythmic action of RSD1235
    • Fedida D, Orth P Chen J, et al. The mechanism of atrial antiarrhythmic action of RSD1235. J Cardiovasc Electrophysiol 2006;16:1227-38
    • (2006) J Cardiovasc Electrophysiol , vol.16 , pp. 1227-1238
    • Fedida, D.1    Orth, P.2    Chen, J.3
  • 6
    • 10644250949 scopus 로고    scopus 로고
    • A randomized, controlled trial of RSD 1235, a novel anti-arrhythmic agent, in the treatment of recent onset atrial fibrillation
    • for the CRAFT Investigators
    • Roy D, Rowe BH, Stiell IG, et al. for the CRAFT Investigators. A randomized, controlled trial of RSD 1235, a novel anti-arrhythmic agent, in the treatment of recent onset atrial fibrillation. J Am Coll Cardiol 2004;44:2355-61
    • (2004) J Am Coll Cardiol , vol.44 , pp. 2355-2361
    • Roy, D.1    Rowe, B.H.2    Stiell, I.G.3
  • 7
    • 34147105609 scopus 로고    scopus 로고
    • (RSD1235): A novel, atrial selective antifibrillatory agent
    • Fedida D. Vernakalant (RSD1235): a novel, atrial selective antifibrillatory agent. Expert Opin Investig Drugs 2007;16:519-32
    • (2007) Expert Opin Investig Drugs , vol.16 , pp. 519-532
    • Vernakalant, F.D.1
  • 8
    • 34548762388 scopus 로고    scopus 로고
    • Vernakalant: A novel antiarrhythmic agent for the treatment of atrial fibrillation
    • Dia EQ, Rathbun RA, Song JC. Vernakalant: a novel antiarrhythmic agent for the treatment of atrial fibrillation. Formulary 2007;42:475-83
    • (2007) Formulary , vol.42 , pp. 475-483
    • Dia, E.Q.1    Rathbun, R.A.2    Song, J.C.3
  • 9
    • 33751527644 scopus 로고    scopus 로고
    • Innovative approaches to anti-arrhythmic therapy
    • Nattel S, Carlsson L. Innovative approaches to anti-arrhythmic therapy. Nat Rev Drug Discov 2006;5:1034-49
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 1034-1049
    • Nattel, S.1    Carlsson, L.2
  • 10
    • 33646535323 scopus 로고    scopus 로고
    • Na and suppresses early afterdepolarizations and torsades de pointes induced by class III agents
    • Na and suppresses early afterdepolarizations and torsades de pointes induced by class III agents. Cardiovasc Res 2006;70:486-96
    • (2006) Cardiovasc Res , vol.70 , pp. 486-496
    • Orth, P.M.R.1    Hesketh, J.C.2    Mak, C.K.H.3
  • 12
    • 34547666917 scopus 로고    scopus 로고
    • The effect of vernakalant (RSD1235), an investigational antiarrhythmic agent on atrial electrophysiology in humans
    • Dorian P, Pinter A, Mangat I, et al. The effect of vernakalant (RSD1235), an investigational antiarrhythmic agent on atrial electrophysiology in humans. J Cardiovasc Pharmacol 2007;50:35-40
    • (2007) J Cardiovasc Pharmacol , vol.50 , pp. 35-40
    • Dorian, P.1    Pinter, A.2    Mangat, I.3
  • 13
    • 34447305364 scopus 로고    scopus 로고
    • RSD1235 for conversion of atrial fibrillation. The phase III Atrial Arrhythmia Conversion Trial
    • Presented at the New Orleans, LA, USA;
    • Roy D, Pratt C, Wyse DG, et al. RSD1235 for conversion of atrial fibrillation. The phase III Atrial Arrhythmia Conversion Trial. Presented at the Heart Rhythm Society 2005 26th Annual Scientific Sessions; New Orleans, LA, USA; 2005
    • (2005) Heart Rhythm Society 2005 26th Annual Scientific Sessions
    • Roy, D.1    Pratt, C.2    Wyse, D.G.3
  • 14
    • 33646925208 scopus 로고    scopus 로고
    • Efficacy and tolerance of RSD1235 in the treatment of atrial fibrillation or atrial flutter: Results of a phase III, randomized, placebo-controlled, multicenter trial [abstract 47]
    • Pratt C, Roy D, Juul-Moller S, et al. Efficacy and tolerance of RSD1235 in the treatment of atrial fibrillation or atrial flutter: results of a phase III, randomized, placebo-controlled, multicenter trial [abstract 47]. J Am Coll Cardiol 2006;10A
    • (2006) J Am Coll Cardiol
    • Pratt, C.1    Roy, D.2    Juul-Moller, S.3
  • 15
    • 34447303677 scopus 로고    scopus 로고
    • Oral vernakalant (RSD1235-SR) prevents recurrence of atrial fibrillation following cardioversion [abstract 4]
    • Pratt CM, Navratil J, Nagy A, et al. Oral vernakalant (RSD1235-SR) prevents recurrence of atrial fibrillation following cardioversion [abstract 4]. Heart Rhythm 2007;S176
    • (2007) Heart Rhythm
    • Pratt, C.M.1    Navratil, J.2    Nagy, A.3
  • 16
    • 45349098858 scopus 로고    scopus 로고
    • Roy D, Pratt C, Camm, AJ, et al. RSD1235 effectively converts atrial fibrillation to sinus rhythm independent of background use of oral rate- or rhythm-control medications [abstract 114]. Circulation 2006;II-790
    • Roy D, Pratt C, Camm, AJ, et al. RSD1235 effectively converts atrial fibrillation to sinus rhythm independent of background use of oral rate- or rhythm-control medications [abstract 114]. Circulation 2006;II-790
  • 17
    • 45349107362 scopus 로고    scopus 로고
    • Kowey PR, Roy D, Pratt CM, et al. Efficacy and safety of vernakalant hydrochloride injection for the treatment of atrial fibrillation after valvular or coronary artery bypass surgery [abstract 16]. Circulation 2007;II-636
    • Kowey PR, Roy D, Pratt CM, et al. Efficacy and safety of vernakalant hydrochloride injection for the treatment of atrial fibrillation after valvular or coronary artery bypass surgery [abstract 16]. Circulation 2007;II-636
  • 18
    • 45349092131 scopus 로고    scopus 로고
    • Astellas Pharma US, Inc. Briefing materials for the cardiovascular and renal drugs advisory committee: December 11, 2007 - Kynapid™ (vernakalant hydrochloride injection). NDA 22-034
    • Astellas Pharma US, Inc. Briefing materials for the cardiovascular and renal drugs advisory committee: December 11, 2007 - Kynapid™ (vernakalant hydrochloride injection). NDA 22-034


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.