A synthesis of heteroaromatic analogues of 1-methyl-1,2,3,4- tetrahydroisoquinoline using the pummerer-type cyclization reaction: Observation of tandem cyclization reaction

Chemical and Pharmaceutical Bulletin

Volumn 52, Issue 2, 2004, Pages 214-220

  Horiguchi, Yoshie ^a   Ogawa, Keita ^a   Saitoh, Toshiaki ^a   Sano, Takehiro ^a  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

11 aza 2 oxa 7 thiatricyclo 4.3.3.01,5 dodecane; Benzofuro 2,3 c pyridine; Benzothieno 2,3 c pyridine; Pummerer reaction; Thieno 2,3 c pyridine

Indexed keywords

1 METHYL 1,2,3,4 TETRAHYDROISOQUINOLINE DERIVATIVE; 1,2,3,4 TETRAHYDRO 1 METHYL 4 PHENYLSULFANYLBENZO[4,5]FURO[2,3 C]PYRIDINE 2 CARBALDEHYDE; 11 AZA 2 OXA 7 THIATRICYCLO[4.3.3.0 1,5 ]DODECANE; 19 FORMYL 18 METHYL 19 AZA 2 OXA 11 THIAPENTACYCLO[8.7.3.0 1,9 .0 3,8 .0 12,17 ]ICOSA 3,5,7,12,14,16 HEXENE; 4,5,6,7 TETRAHYDRO 7 METHYL 4 PHENYLSULFANYLTHIENO[2,3 C]PYRIDINE 6 CARBALDEHYDE; ALDEHYDE DERIVATIVE; ALKANE DERIVATIVE; BENZOFURAN DERIVATIVE; BENZOTHIOPHENE; BENZOTHIOPHENE DERIVATIVE; ISOQUINOLINE DERIVATIVE; NITROGEN; OXONIC ACID; SULFOXIDE; THIOPHENE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG; 1 METHYL 1,2,3,4 TETRAHYDROISOQUINOLINE; 1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE; TETRAHYDROISOQUINOLINE DERIVATIVE;

ALKYLATION; ARTICLE; CHEMICAL REACTION KINETICS; CYCLIZATION; DIASTEREOISOMER; DRUG SYNTHESIS; PUMMERER REACTION; QUANTUM YIELD; REACTION ANALYSIS; ROOM TEMPERATURE; CHEMICAL STRUCTURE; CHEMISTRY; HYDROLYSIS; OXIDATION REDUCTION REACTION; STEREOISOMERISM; SYNTHESIS;

CYCLIZATION; HYDROLYSIS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; STEREOISOMERISM; SULFOXIDES; TETRAHYDROISOQUINOLINES;

EID: 4444379637     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.52.214     Document Type: Article

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