An improved synthesis of 1,2,3,4-tetrahydroisoquinolines via intramolecular cyclization of N-acyl-N-(aryl)methyl-2- (phenylsulfinyl)ethylamine by Pummerer reaction

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 5, 1997, Pages 813-819

  Shinohara, Tatsumi ^a   Toda, Jun ^b   Sano, Takehiro ^b  

^a Laboratory of Racing Chemistry   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

1,2,3,4 tetrahydroisoquinoline; Boron trifluoride etherate; Isoquinoline; Pummerer reaction; Trifluoroacetic anhydride

Indexed keywords

ACETIC ANHYDRIDE; BENZENE; ETHYLAMINE; N ACYL 4 PHENYLTHIO 1,2,3,4 TETRAHYDROISOQUINOLINE; SULFOXIDE; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CYCLIZATION; DESULFURIZATION; HYDROLYSIS; INFRARED SPECTROMETRY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; OXIDATION; SYNTHESIS;

EID: 0030956010     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.813     Document Type: Article

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