The risk assessment paradigm and its application for trichothecenes

Toxicology Letters

Volumn 153, Issue 1, 2004, Pages 155-163

  Tritscher, Angelika M ^a   Page, Samuel W ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Deoxynivalenol; Mycotoxin; Nivalenol; Risk assessment; T 2 and HT 2 toxins; Trichothecenes

Indexed keywords

HT 2 TOXIN; MYCOTOXIN; NIVALENOL; T 2 TOXIN; TRICHOTHECENE DERIVATIVE; VOMITOXIN;

CONFERENCE PAPER; FOOD CONTAMINATION; FOOD POISONING; HUMAN; MEDICAL RESEARCH; PRIORITY JOURNAL; RISK ASSESSMENT; RISK MANAGEMENT;

ANIMALS; CHILD; CHILD, PRESCHOOL; CONSUMER PRODUCT SAFETY; FEMALE; FOOD CONTAMINATION; FOOD POISONING; HUMANS; INFANT; MALE; MICE; RISK ASSESSMENT; TRICHOTHECENES;

EID: 4444377525     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.04.030     Document Type: Conference Paper

References (21)

1. Canady R.A., Coker R.D., Egan S.K., Krska R., Kuiper-Goodman T., Olsen M., Pestka J., Resnik S., Schlatter J. Deoxynivalenol. In WHO/IPCS Safety evaluation of certain mycotoxins in food. WHO Food Addit. Ser. 47:2001;419-555. http://www.inchem.org/documents/jecfa/jecmono/v47je05.htm
2. Canady R.A., Coker R.D., Egan S.K., Krska R., Olsen M., Resnik S., Schlatter J. T-2 and HT-2 toxins. In WHO/IPCS Safety evaluation of certain mycotoxins in food. WHO Food Addit. Ser. 47:2001a;557-680. http://www.inchem. org/documents/jecfa/jecmono/v47je06.htm
3. Codex Alimentarius Commission, Report of the 26th Session of the Codex Alimentarius Commission, 2003, ALINORM 03/41, Appendix IV. http://www.fao.org/ codex/alinorm03/a103_41e.pdf.
4. Eriksen, G.S., Alexander, J. (Eds.) 1998. Fusarium toxins in cereals - a Risk Assessment. Nordic Council of Ministers, TemaNord 502, Copenhagen, pp. 7-44.
5. National Research Council, 1983. Risk Assessment in the Federal Government: Managing the Process. NAS Press, Washington, DC, USA.
6. FAO/WHO, 2002. Pesticide residues in food 2002, FAO Plant Production and Protection Paper, 172, Rome, pp. 4-8.
7. Larsen J.C., Richold M. Report of Workshop on the Significance of Excursions above the ADI. Reg. Toxicol. Pharmacol. 30(2):1999;S2-S12
8. Meky F.A., Hardic L.J., Evans S.W., Wild C.P. Deoxynivalenol-induced immunomodulation of human lympocyte proliferation and cytokine production. Food. Chem. Toxicol. 39(8):2001;827-836
9. Meky F.A., Turner P.C., Ashcroft A.E., Miller J.D., Qiao Y.L., Roth M.J., Wild C.P. Development of a urinary biomarker of human exposure to deoxynivalenol. Food. Chem. Toxicol. 41(2):2003;265-273
10. Pestka, J., 2004. Cellular and Molecular Effects, Including Immunotoxic Effects. Toxicol Lett, this issue.
11. Pieters, M.N., Bakker, M., 2004. Probabilistic exposure models. Toxicol Lett, this issue.
12. Pieters, M.N., Freijer, J., Baars, A.J., Slob, W., 2001. Risk Assessment of Deoxynivalenol in Food. RIVM report 388802 022, Rijks Instituut voor Volksgezondheid en Milieu, Bilthoven, The Netherlands.
13. Renwick A.G., et al. Risk characterisation of chemicals in food and diet. Food Chem. Tox. 41:2003;1211-1271
14. Schothorst, R., van Egmond, H.P., 2004. Critical Assessment of Exposure - Report from the Scoop Project. Toxicol Lett, this issue.
15. Scientific Committee on Food, 1999. Opinion on Fusarium Toxins-Part 1: Deoxynivalenol DON) (expressed on 2 December 1999) http://europa.eu.int/comm/ food/fs/sc/scf/out44_en.html.
16. Scientific Committee on Food, 2000. Opinion on Fusarium Toxins Part 4: Nivalenol. http://europa.eu.int/comm/food/fs/sc/scf/out185_en.pdf.
17. Scientific Committee on Food, 2001. Opinion on Fusarium Toxins, Part 5: T-2 toxin and HT-2 toxin. http://europa.eu.int/comm/food/fs/sc/scf/out88_en.pdf.
18. Scientific Committee on Food, 2002. Opinion on Fusarium Toxins. Part 6: Group evaluation of T-2 toxin, HT-2 toxin, nivalenol and deoxynivalenol. http://europa.eu.int/comm/food/fs/sc/scf/out123_en.pdf.
19. Schlatter, J., 2004. Toxicity data relevant to hazard characterization. Toxicol Lett, this issue.
20. Speijers, G.J.A., Speijers, M.H.M., 2004. Combined toxic effects. Toxicol Lett, this issue.
21. WHO, 1998. GEMS/Food Regional Diets. Regional Per Capita Consumption of Raw and Semi-processed Agricultural Commodities (WHO/FSF/FOS/98.3), Geneva.