Vaccination protects B cell-deficient mice against an oral challenge with mildly virulent Toxoplasma gondii

Vaccine

Volumn 22, Issue 29-30, 2004, Pages 4054-4061

  Johnson, Lawrence L ^a   Lanthier, Paula ^a   Hoffman, Jessica ^a   Chen, Wangxue ^b  

^a TRUDEAU INSTITUTE   (United States)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

B cells; Toxoplasma gondii; Vaccination

Indexed keywords

PROTOZOAL VACCINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATTENUATION; B LYMPHOCYTE; CONTROLLED STUDY; CYST; CYTOKINE PRODUCTION; FEMALE; HISTOPATHOLOGY; IMMUNE RESPONSE; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTOZOAL INFECTION; TOXOPLASMA GONDII; VACCINATION; VIRULENCE;

ANIMALS; B-LYMPHOCYTES; CYTOKINES; FEMALE; GENE EXPRESSION; ILEUM; INTERFERON TYPE II; INTERLEUKIN-10; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTOZOAN VACCINES; RNA, MESSENGER; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; TUMOR NECROSIS FACTOR-ALPHA; VACCINATION;

EID: 4444376796     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.03.056     Document Type: Article

References (40)

1. McCabe RE, Remington JS, Toxoplasma gondii. In: Mandell GL, Douglas JRG, Bennett JE, editors. Principles and practices of infectious diseases. New York: Churchill Livingstone, Inc.; 1990. p. 2090.
2. McLeod R, Remington JS, Toxoplasmosis. In: Wilson JD et al., editors. Harrison's principles of internal medicine. New York: McGraw-Hill; 1991. p. 879.
3. Remington JS, McLeod R, Desmonts G. Toxoplasmosis. In: Remington JS, Klein JO, editors. Infectious diseases of the fetus and newborn infant. PA: W.B. Saunders Company; 1995, p. 140.
4. Roberts C.W., Alexander J. Studies on a murine model of congenital toxoplasmosis: vertical disease transmission only occurs in BALB/c mice infected for the first time during pregnancy. Parasitology. 104(Pt 1):1992;19
5. Bout D.T., Mevelec M.N., Velge-Roussel F., Dimier-Poisson I., Lebrun M. Prospects for a human Toxoplasma vaccine. Curr. Drug Targets Immune Endocr. Metabol. Disord. 2:2002;227
6. Buxton D., Innes E.A. A commercial vaccine for ovine toxoplasmosis. Parasitology. 110:1995;S11
7. + T lymphocytes in IFN-g production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. J Immunol. 146(1):1991;286
8. + T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii. J. Immunol. 149(1):1992;175
9. + T cell-mediated immunity in mice infected with a vaccine strain of Toxoplasma gondii. J. Immunol. 163:1998;4503
10. + T cells are the major lymphocyte subpopulation involved in the protective immune response to Toxoplasma gondii in mice. Clin Exp Immunol. 84(2):1991;207
11. Denkers E.Y., Gazzinelli R.T. Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection. Clin. Microb. Rev. 11:1998;569
12. + T cells in mice. J Immunol. 140(11):1988;3943
13. + immune T cells against toxoplasmosis in mice. J Immunol. 144(5):1990;1954
14. Sayles P.C., Gibson G.W., Johnson L.L. B cells are essential for vaccination-induced resistance to virulent Toxoplasma gondii. Infect. Immun. 68:2000;1026
15. Johnson L.L., Sayles P.C. Deficient humoral responses underlie susceptibility to Toxoplasma gondii in CD4-deficient mice. Infect. Immun. 70:2002;185
16. Howe D.K., Sibley L.D. Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease. J. Infect. Dis. 172:1995;1561
17. Sibley L.D., Boothroyd J.C. Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature. 359:1992;82
18. Gavrilescu L.C., Denkers E.Y. IFN-g overproduction and high level apoptosis are associated with high but not low virulence Toxoplasma gondii infection. J. Immunol. 167:2001;902
19. Mordue D.G., Monroy F., LaRegina M., Dinarello C.A., Sibley L.D. Acute toxoplasmosis leads to lethal overproduction of Th1 cytokines. J. Immunol. 167:2001;4574
20. Howe D.K., Honore S., Derouin F., Sibley L.D. Determination of genotypes of Toxoplasma gondii strains isolated from patients with toxoplasmosis. J. Clin. Microbiol. 35:1997;1411
21. Kitamura D., Roes J., Kuhn R., Rajewsky K. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin m chain gene. Nature. 350:1991;423
22. Pfefferkorn E.R., Pfefferkorn L.C. Toxoplasma gondii: isolation and preliminary characterization of temperature-sensitive mutants. Exp Parasitol. 39(3):1976;365
23. Johnson L.L. SCID mouse models of acute and relapsing chronic Toxoplasma gondii infections. Infect Immun. 60(9):1992;3719
24. + lymphocytes. Infect Immun. 61(12):1993;5174
25. Cozon G., Roure C., Lizard G., Greenland T., Larget-Piet D., Gandilhon F., et al. An improved assay for the detection of Toxoplasma gondii antibodies in human serum by flow cytometry. Cytometry. 14:1993;569
26. Kasper L.H., Bradley M.S., Pfefferkorn E.R. Identification of stage-specific sporozoite antigens of Toxoplasma gondii by monoclonal antobodies. J. Immunol. 132:1984;443
27. Johnson L.L., Berggren K.N., Szaba F.M., Chen W., Smiley S.T. Fibrin-mediated protection against infection-stimulated pathology. J. Exp. Med. 197:2003;801
28. Waldeland H., Pfefferkorn E.R., Frenkel J.K. Temperature-sensitive mutants of Toxoplasma gondii: pathogenicity and persistence in mice. J Parasitol. 69(1):1983;171
29. McLeod R., Frenkel J.K., Estes R.G., Mack D.G., Eisenhauer P.B., Gibori G. Subcutaneous and intestinal vaccination with tachyzoites of Toxoplasma gondii and acquisition of immunity to peroral and congenital toxoplasma challenge. J Immunol. 140(5):1988;1632
30. Khan I.A., Matsuura T., Kasper L.H. Inducible nitric oxide synthase is not required for long-term vaccine-based immunity against Toxoplasma gondii. J. Immunol. 161:1998;2994
31. + T cell-dependent interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J. Exp. Med. 184:1996;597
32. Liesenfeld O., Nguyen T.A., Pharice C., Suzuki Y. Importance of gender and sex hormones in regulation of susceptibility of the small intestine to peroral infection with Toxoplasma gondii tissue cysts. J. Parasitol. 87:2001;1491-1493
33. Suzuki Y., Sher A., Yap G., Park D., Neyer L.E., Liesenfeld O., et al. IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii. J. Immunol. 164:2000;5375
34. Liesenfeld O., Kang H., Park D., Nguyen T.A., Parkhe C.V., Watanabe H., et al. TNF-alpha, nitric oxide, and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii. Parasite Immunol. 21:1999;365
35. Kang H., Remington J.S., Suzuki Y. Decreased resistance of B cell-deficient mice to infection with Toxoplasma gondii despite unimpaired expression of IFN-g, TNF-a, and inducible nitric oxide synthase. J. Immunol. 164:2000;2629
36. MacPherson A.J., Lamarre A., McCoy K., Harriman G.R., Odermatt B., Dougan G., et al. IgA production without mu or delta chain expression in developing B cells. Nat. Immunol. 2:2001;625
37. Chardes T., Bourguin I., Mevelec M.N., Dubremetz J.F., Bout D. Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens. Infect Immun. 58(5):1990;1240
38. McLeod R., Mack D.G. Secretory IgA specific for Toxoplasma gondii. J Immunol. 136(7):1986;2640
39. Mineo J.R., McLeod R., Mack D., Smith J., Khan I.A., Ely K.H., et al. Antibodies to Toxoplasma gondii major surface protein (SAG-1, P30) inhibit infection of host cells and are produced in murine intestine after peroral infection. J Immunol. 150(9):1993;3951
40. + regulatory T cells control Leishmania major persistence and immunity. Nature. 420:2002;502