Development of a high-throughput screen for inhibitors of replication protein A and its role in nucleotide excision repair

Molecular Cancer Therapeutics

Volumn 3, Issue 4, 2004, Pages 385-391

  Andrews, Brooke J ^a   Turchi, John J ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DNA; DOUBLE STRANDED DNA; NUCLEOTIDE; PROTEIN INHIBITOR; REPLICATION PROTEIN A; REPLICATION PROTEIN A INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DETERMINATION; DRUG DNA BINDING; DRUG POTENCY; DRUG RESISTANCE; EXCISION REPAIR; EXPERIMENTATION; FLUORESCENCE ANALYSIS; FLUORESCENCE POLARIZATION; GEL MOBILITY SHIFT ASSAY; HIGH THROUGHPUT SCREENING; HUMAN; IC 50; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; REPORTER GENE; SCORING SYSTEM; TITRIMETRY; VALIDATION PROCESS;

ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; DNA DAMAGE; DNA REPAIR; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, NEOPLASM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLUORESCENCE POLARIZATION; FLUORESCENT DYES; HUMANS; INHIBITORY CONCENTRATION 50; PROTEIN BINDING; REPLICATION PROTEIN A; REPRODUCIBILITY OF RESULTS;

EID: 4444372436     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

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