Effect of ecdysterone on the expression of c-fos in the brain of rats induced by microinjection β-AP25-35 into the hippocampus

Yaoxue Xuebao

Volumn 39, Issue 4, 2004, Pages 241-244

  Yang, Su Fen ^a,b   Yang, Zheng Qin ^a   Zhou, Qi Xin ^a   Wu, Qin ^b   Huang, Xie Nan ^b   Shi, Jing Shan ^b  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b ZUNYI MEDICAL UNIVERSITY   (China)

Author keywords

AP25 35; c fos; Ecdysterone; Hippocampus

Indexed keywords

ECDYSTERONE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); PEPTIDE FRAGMENT; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG EFFECT; HIPPOCAMPUS; LEARNING; LEARNING DISORDER; MAZE TEST; MEMORY; MEMORY DISORDER; MICROINJECTION; MOLECULAR DYNAMICS; NONHUMAN; ONCOGENE C FOS; PROTEIN EXPRESSION; RAT; ANIMAL; DRUG ANTAGONISM; GENE EXPRESSION; MALE; METABOLISM; ONCOGENE; WISTAR RAT;

AMYLOID BETA-PROTEIN; ANIMALS; ECDYSTERONE; GENE EXPRESSION; GENES, FOS; HIPPOCAMPUS; MALE; MAZE LEARNING; MICROINJECTIONS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR;

EID: 4444359990     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. 25-35-induced memory impaired rats [J]. Acta Pharm Sin, 2003,38(10):721-724.
2. 25-35 on voltage-gated patassium outward current in cultured rat hippocampal neurons [J]. Acta Pharm Sin, 2001,36(12):898-901.
3. Alkon DL. Calcium-mediated reduction of ionic currents: a biophysical memory trace [J]. Science, 1984,226(4678):1037-1045.
4. Zhang YQ, Mei J. The effect of learning and memory on c-fos gene expression in brain [J]. Chin Bull Life Sci, 2000,12(5):228-231.
5. Otaka T, Okui S, Uchiyama M, et al. Stimulation of protein synthesis in mouse liver by ecdysterone [J]. Chem Pharm Bull, 1969,17(1):75-81.
6. Otaka T, Uchiyama M. Stimulatory effect of ecdysterone on RNA synthesis in mouse liver [J]. Chem Pharm Bull, 1969,17(9):1883-1888.
7. Yoshida T, Otaka T, Uchiyama M, et al. Effect of ecdysterone on hyperglycemia in experimental animals [J]. Biochem Pharm, 1971,20(12):3263-3268.
8. Catalan RE. Alterations in rat lipid metabolism following ecdysterone treatment [J]. Comp Biochem Physicol, 1985,81B(3):771-775.
9. Kuzmitskii BB, Golubeva MB, konoplia NA, et al. New possibilities in searching for immunomodulation among compounds with a steriod structure [J]. 1990,53(3):20-22.
10. Catalan RE, Aragones MD, Godoy JE, et al. Ecdysterone induces acetylcholinesterase in mammalian brain [J]. Comp Biochem Physiol, 1984,78c(1):193-195.
11. Morimoto K, Yoshimi K, Tonohiro T, et al. Co-injection of β-amyloid with ibotenic acid induces synergistic loss of rat hippocampal neurons [J]. Neuroscience, 1998,84(2):479-487.
12. Wang XL, Chen J, Zhang JT. Effect of ginsenoside Rgl on learning and memory impairment induced by β-amyloid peptides (25-35) and its mechanism of action [J]. Acta Pharm Sin, 2001,36(1):1-4.
13. Wang H, Shu SY, Bao XM, et al. Expression of immediate-early genes c-fos and c-jun in the marginal division of striatum during learning and memory [J]. Acad J First Med Coll PLA. 2002,22(1):9-12.
14. Mileusnic R, Anokhin K, Rose SP. Antisense oligodeoxynucleotides to c-fos are amnestic for passive avoidance in the chick [J]. Neuroreport, 1996, 7(7):1269-1272.
15. Ashburner M, Richards G. Sequential gene activation by ecdysone in polytene chromosones of Drosophila melanogaster. III. Consequences of ecdysone withdral [J]. Dev Biol, 1976,54(2):241-255.