Synthesis and biological evaluation of carbocyclic nucleosides with 2′,3′-dihomo-xylo-carbocyclic or carbocyclic fused to a tetrahydrofuran ring

Synthesis

Volumn , Issue 12, 2004, Pages 1991-1995

  Figueira, María José ^a   Caamaño, Olga ^a   Fernández, Franco ^a   Rodríguez Borges, J Enrique ^b   Balzarini, Jan ^c   De Clercq, Erik ^c  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSITY OF PORTO   (Portugal)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Antitumoral activity; Antiviral; Synthesis; Tetrahydrofuran derivatives; xylo carbocyclic nucleosides

Indexed keywords

CONDENSATION; DISEASE CONTROL; DRUG PRODUCTS; METHANOL; TUMORS;

ANTITUMOR ACTIVITY; ANTIVIRAL ACTIVITY;

SYNTHESIS (CHEMICAL);

4 (7' AMINO 3'H 1',2'3' TRIAZOLO[4',5' D]PYRIMIDIN 3' YL) 1,2,3 CYCLOPENTANETRIMETHANOL; 6,7 DIHYDRO 3 [2',3',4' TRIS(HYDROXYMETHYL) 1' CYCLOPENTYL] 3H 1,2,3 TRIAZOLO[4,5 D]PYRIMIDIN 7 ONE; 6,9 DIHYDRO 9 [6' (HYDROXYMETHYL) 3' OXABICYCLO[3.3.0]OCT 7' YL] 1H PURIN 6 ONE; [7 (6' AMINO 9'H PURIN 9' YL) 3 OXABICYCLO[3.3.0]OCT 6 YL]METHANOL; ALKANE DERIVATIVE; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; CARBOCYCLIC NUCLEOSIDE; CARBOXYL GROUP; METHANOL DERIVATIVE; PYRIMIDINE DERIVATIVE; TETRAHYDROFURAN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CHROMATOGRAPHY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; NONHUMAN; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY CRYSTALLOGRAPHY;

EID: 4444309369     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-829141     Document Type: Article

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