Changes in the expression of angiotensin II type 1 receptor in the development of liver fibrosis

Chinese Journal of Digestive Diseases

Volumn 5, Issue 3, 2004, Pages 118-122

  Wang, Wei Wei ^a   Yang, Xi Shan ^a   Li, Xu ^a   Wang, Jie ^a   Tian, Ye ^a   Yang, Chuan Hong ^a   Lai, Huang Wen ^a  

^a GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

Author keywords

Angiotensin II receptor; Gene expression; Hepatic stellate cells; Liver fibrosis

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; COLLAGEN TYPE 1; MESSENGER RNA;

ADULT; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CYTOPLASM; DISEASE COURSE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER FIBROSIS; LIVER SINUSOID; LIVER STRUCTURE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; TRANSMISSION ELECTRON MICROSCOPY;

ADOLESCENT; ADULT; CADAVER; CASE-CONTROL STUDIES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER CIRRHOSIS; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; RECEPTOR, ANGIOTENSIN, TYPE 1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 4444284019     PISSN: 14439611     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1443-9573.2004.00165.x     Document Type: Article

References (11)

1. Bataller R, Gines P, Nicolas JM et al. Angiotensin II induces contraction and proliferation of human hepatic stellate cells. Gastroenterology 2000; 118: 1149-56.
2. Zhang J, Zong CH, Li DG et al. Hepatic stellate cells exists as a local renin-angiotensin-aldosterone system. Chin J Dig 2003; 23: 38-40.
3. Wei H, Li D, Lu H et al. Effects of AT1 receptor antagonist losartan on rat hepatic fibrosis induced by CCL4. World J Gastroenterol 2000; 6: 540-5.
4. Hepatic Fibrosis Study Group 2002. Consensus on the evaluation of the diagnosis and efficacy of hepatic fibrosis. Chin J Hepatol 10, 327-8.
5. Quan QZ, Sun ZQ, Wang YJ. New Hepatology, 1st edn. Shandong Science and Technology Publisher, 2003.
6. Mifune M, Sasamura H, Shimizu H et al. Angiotensin II type 2 receptor stimulates collagen synthesis in cultured vascular smooth muscle cells. Hypertension 2000; 36: 845-50.
7. Lim D, Lutucuta S, Bachireddy P et al. Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy. Circulation 2001; 103: 789-91.
8. Yoshiji H, Kuriyama S, Yoshii J et al. Angiotensin II type 1 receptor interaction is a major regulator for liver fibrosis development in rats. Hepatology 2001; 34: 745-50.
9. Li X et al. Expression of CYP11B2 in HSCs and the curative effect of anti-aldosterone on hepatic fibrosis. Chin J Med 2001; 114: 64-8.
10. Li X, Yang XS, Wu PS et al. Study of CYP11B2 expression in HSCs of rat's liver. Chin J Dig 2000; 20: 167-70.
11. Li X, Yang XS, Wu PS et al. CYP11B2 expression in rat liver and the efficacy of anti-aldosterone on liver fibrosis. Chin J Hepatol 2001; 9: 75-7.