Restriction of BMP4 activity domains in the developing neural tube of the mouse embryo

EMBO Reports

Volumn 5, Issue 7, 2004, Pages 734-739

  Hu, Qiyong ^a   Ueno, Naoto ^b   Behringer, Richard R ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

Author keywords

BMP; Dorsovental pattern; Neural tube; Transgenic mouse

Indexed keywords

AMINO ACID; BETA GALACTOSIDASE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; WNT1 PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; GENE ACTIVATION; GENE ACTIVITY; GENE MUTATION; GENE OVEREXPRESSION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL TUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; SPINAL CORD; STEM CELL; TRANSGENE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BODY PATTERNING; BONE MORPHOGENETIC PROTEINS; CROSSES, GENETIC; EMBRYO; GENETIC VECTORS; GENOTYPE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NEURAL CREST; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPINAL CORD; TRANSGENES;

MUS MUSCULUS; VERTEBRATA;

EID: 4444281040     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400184     Document Type: Article

References (27)

1. Barth KA, Kishimoto Y, Rohr KB, Seydler C, Schulte-Merker S, Wilson SW (1999) Bmp activity establishes a gradient of positional information throughout the entire neural plate. Development 126: 4977-4987
2. Bendall AJ, Abate-Shen C (2000) Roles for Msx and Dlx homeoproteins in vertebrate development. Gene 247: 17-31
3. Bernfield M, Gotte M, Park PW, Reizes O, Fitzgerald ML, Lincecum J, Zako M (1999) Functions of cell surface heparan sulfate proteoglycans. Annu Rev Biochem 68: 729-777
4. Brand AH, Perrimon N (1993) Development 118: 401-415
5. Briscoe J, Ericson J (2001) Specification of neuronal fates in the ventral neural tube. Curr Opin Neurobiol 11: 43-49
6. Briscoe J, Sussel L, Serup P, Hartigan-O'Connor D, Jessell TM, Rubenstein JL, Ericson J (1999) Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature 398: 622-627
7. Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA (1996) Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383: 407-413
8. Dudley AT, Robertson EJ (1997) Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos. Dev Dyn 208: 349-362
9. Ericson J, Rashbass P, Schedl A, Brenner-Morton S, Kawakami A, Van Heyningen V, Jessell TM, Briscoe J (1997) Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90: 169-180
10. Forsberg E, Kjellen L (2001) Heparan sulfate: lessons from knockout mice. J Clin Invest 108: 175-180
11. Hartmann U, Maurer P (2001) Proteoglycans in the nervous system - the quest for functional roles in vivo. Matrix Biol 20: 23-35
12. Hynes M, Poulsen K, Tessier-Lavigne M, Rosenthal A (1995) Control of neuronal diversity by the floor plate: contact-mediated induction of midbrain dopaminergic neurons. Cell 80: 95-101
13. Koenig BB, Cook JS, Wolsing DH, Ting J, Tiesman JP, Correa PE, Olson CA, Ventura F, Crant RA (1994) Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. Mol Cell Biol 14: 5961-5974
14. Lee KJ, Mendelsohn M, Jessell TM (1998) Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord. Genes Dev 12: 3394-3407
15. Liem KF, Tremml G, Roelink H, Jessell TM (1995) Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 82: 969-979
16. Liem Jr KF, Jessell TM, Briscoe J (2000) Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites. Development 127: 4855-4866
17. Liu P, Wakamiya M, Shea MJ, Albrecht U, Behringer RR, Bradley A (1999) Requirement for Wnt3 in vertebrate axis formation. Nat Genet 22: 361-365
18. McMahon JA, Takada S, Zimmerman LB, Fan CM, Harland RM, McMahon AP (1998) Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev 12: 1438-1452
19. Nguyen VH, Trout J, Connors SA, Andermann P, Weinberg E, Mullins MC (2000) Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway. Development 127: 1209-1220
20. Ohkawara B, Iemura S, ten Dijke P, Ueno N (2002) Action range of BMP is defined by its N-terminal basic amino acid core. Curr Biol 12: 205-209
21. Rowitch DH, S-Jacques B, Lee SM, Flax JD, Snyder EY, McMahon AP (1999) Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci 19: 8954-8965
22. Ruppert R, Hoffmann E, Sebald W (1996) Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activity. Eur J Biochem 237: 295-302
23. Sasaki H, Hogan BL (1993) Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development 118: 47-59
24. Vincent JP, Briscoe J (2001) Morphogens. Curr Biol 11: 851-854
25. Wang SW, Kim BS, Ding K, Wang H, Sun D, Johnson RL, Klein WH, Gan L (2001) Requirement for math5 in the development of retinal ganglion cells. Genes Dev 15: 24-29
26. Wilkinson DG (1992), in In Situ Hybridization: A Practical Approach, (ed. Wilkinson DG) 75-83. IRL Press: Oxford, UK
27. Zhang H, Hasty P, Bradley A (1994) Targeting frequency for deletion vectors in embryonic stem cells. Mol Cell Biol 14: 2404-2410