A unique mechanism for cyclic adenosine 3′,5′-monophosphate- induced increase of 32-kDa tyrosine-phosphorylated protein in boar spermatozoa

Molecular Reproduction and Development

Volumn 69, Issue 2, 2004, Pages 194-204

  Harayama, Hiroshi ^a   Sasaki, Kiyomi ^a   Miyake, Masashi ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

Calcium; cAMP; Lavendustin A; Sperm; Tyrosine phosphorylation; Vanadate

Indexed keywords

5,6 DICHLORO 1 BETA DEXTRO RIBOFURANOSYLBENZIMIDAZOLE 3',5' MONOPHOSPHOROTHIOATE; CALCIUM; CALCIUM CHELATING AGENT; CALCIUM CHLORIDE; CYCLIC AMP; CYCLIC AMP DERIVATIVE; ENZYME INHIBITOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL) ESTER; LAVENDUSTIN A; METHYL BETA CYCLODEXTRIN; PHOSPHATASE; PHOSPHOPROTEIN; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE INHIBITOR; REGULATOR PROTEIN; UNCLASSIFIED DRUG; VANADATE SODIUM;

ACROSOME; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CONCENTRATION RESPONSE; CULTURE MEDIUM; EXTRACELLULAR CALCIUM; FERTILIZATION; GIEMSA STAIN; IMMUNOFLUORESCENCE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPERMATOZOON; SWINE; WESTERN BLOTTING;

ACROSOME; ANIMALS; BETA-CYCLODEXTRINS; CALCIUM; CHELATING AGENTS; CYCLIC AMP; EGTAZIC ACID; MALE; PHENOLS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; SIGNAL TRANSDUCTION; SPERMATOZOA; SWINE; TYROSINE; VANADATES;

MAMMALIA;

EID: 4444280587     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.20099     Document Type: Article

References (40)

1. Aitken RJ, Harkiss D, Knox W, Paterson M, Irvine DS. 1998. A novel signal transduction cascade in capacitating human spermatozoa characterized by a redox-regulated, cAMP-mediated induction of tyrosine phosphorylation. J Cell Sci 111:645-656.
2. Beavo JA, Brunton LL. 2002. Cyclic nucleotide research: Still expanding after half a century. Nat Rev Mol Cell Biol 3:710-718.
3. Bjerrum OJ, Schafer-Nielsen C. 1986. Buffer system and transfer parameters for semi dry electroblotting with a horizontal apparatus. In: Dunn MJ, editor. Analytical electrophoresis. Weinheim: Verlag Chemie. pp 315-327.
4. Bos JL. 2003. Epac: A new cAMP target and new avenues in cAMP research. Nat Rev Mol Cell Biol 4:733-738.
5. Breitbart H. 2002. Intracellular calcium regulation in sperm capacitation and acrosomal reaction. Mol Cell Endocrinol 187:139-144.
6. Brener E, Rubinstein S, Cohen G, Shternall K, Rivlin J, Breitbart H. 2003. Remodeling of the actin cytoskeleton during mammalian sperm capacitation and acrosome reaction. Biol Reprod 68:837-845.
7. De Vries KJ, Wiedmer T, Sims PJ, Gadella BM. 2003. Caspase-independent exposure of aminophospholipids and tyrosine phosphorylation in bicarbonate responsive human sperm cells. Biol Reprod 68:2122-2134.
8. Dinkins MB, Brackett BG. 2000. Chlortetracycline staining patterns of frozen-thawed bull spermatozoa treated with β-cyclodextrins, dibutyryl cAMP, and progesterone. Zygote 8:245-256.
9. 2+ store depletion during human sperm acrosome reaction. Mol Hum Reprod 9:125-131.
10. Eddy EM, Toshimori K, O'Brien DA. 2003. Fibrous sheath of mammalian spermatozoa. Microsc Res Tech 61:103-115.
11. Flesch FM, Colenbrander B, van Golde LM, Gadella BM. 1999. Capacitation induces tyrosine phosphorylation of proteins in the boar sperm plasma membrane. Biochem Biophys Res Commun 262:787-792.
12. Flesch FM, Brouwers JF, Nievelstein PF, Verkleij AJ, van Golde LM, Colenbrander B, Gadella BM. 2001a. Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane. J Cell Sci 114:3543-3555.
13. Flesch FM, Wijnand E, van de Lest CH, Colenbrander B, van Golde LM, Gadella BM. 2001b. Capacitation dependent activation of tyrosine phosphorylation generates two sperm head plasma membrane proteins with high primary binding affinity for the zona pellucida. Mol Reprod Dev 60:107-115.
14. Fraser LR, Dudley K. 1999. New insights into t-complex and control of sperm function. BioEssay 21:304-312.
15. Gadella BM, Harrison RA. 2002. Capacitation induces cyclic adenosine 3′,5′-monophosphate-dependent, but apoptosis-unrelated, exposure of aminophospholipids at the apical head plasma membrane of boar sperm cells. Biol Reprod 67:340-350.
16. Harayama H. 2003. Viability and protein phosphorylation patterns of boar spermatozoa agglutinated by the treatment with a cell-permeable cyclic adenosine 3′,5′-monophosphate analog. J Androl 24:831-842.
17. Harayama H, Magargee SF, Kunze E, Shidara O, Iwamoto E, Arikawa S, Miyake M, Kato S, Hammerstedt RH. 1999. Changes in epididymal protein anti-agglutinin on ejaculated boar spermatozoa during capacitation in vitro. Reprod Fertil Dev 11:193-199.
18. Harayama H, Miyake M, Kato S. 2000. Role of cyclic adenosine 3′,5′-monophosphate and serum albumin in head-to-head agglutination of boar spermatozoa. Reprod Fertil Dev 12:307-318.
19. Harayama H, Okada K, Miyake M. 2003. Involvement of cytoplasmic free calcium in boar sperm: Head-to-head agglutination induced by a cell-permeable cyclic adenosine monophosphate analog. J Androl 24:91-99.
20. Harrison RAP, Miller NGA. 2000. cAMP-dependent protein kinase control of plasma membrane lipid architecture in boar sperm. Mol Reprod Dev 55:220-228.
21. Ho HC, Suarez SS. 2001. Hyperactivation of mammalian spermatozoa: Function and regulation. Reproduction 122:519-526.
22. Hurley JH. 1999. Structure, mechanism, and regulation of mammalian adenylyl cyclase. J Biol Chem 274:7599-7602.
23. Kaneto M, Harayama H, Miyake M, Kato S. 2002. Capacitation-like alterations in cooled boar spermatozoa: Assessment by the chlortetracycline staining assay and immunodetection of tyrosine-phosphorylated sperm proteins. Anim Reprod Sci 73:197-209.
24. Kaupp UB, Weyand I. 2000. A universal bicarbonate sensor. Science 289:559-560.
25. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
26. 2+. Biol Reprod 67:301-307.
27. Leyton L, Baling P. 1989. 95 kDa sperm proteins bind ZP3 and serve as tyrosine kinase substrates in response to zona binding. Cell 57:1123-1130.
28. Motulsky H. 1995. Intuitive biostatistics. New York: Oxford University Press.
29. Okamura N, Tajima Y, Soejima A, Masuda H, Suguta Y. 1985. Sodium bicarbonate in seminal plasma stimulates the motility of mammalian spermatozoa through direct activation of adenylate cyclase. J Biol Chem 260:9699-9705.
30. Okamura N, Tajima Y, Sugita Y. 1988. Decrease in bicarbonate transport activities during epididymal maturation of porcine sperm. Biochem Biophys Res Commun 157:1280-1287.
31. Schaap P, van Ments-Cohen M, Soede RD, Brandt R, Firtel RA, Dostmann W, Genieser HG, Jastorff B, van Haastert PJ. 1993. Cell-permeable non-hydrolyzable cAMP derivatives as tools for analysis of signaling pathways controlling gene regulation in Dictyostelium. J Biol Chem 268:6323-6331.
32. Tardif S, Dúbe C, Chevalier S, Bailey JL. 2001. Capacitation is associated with tyrosine phosphorylation and tyrosine kinase-like activity of pig sperm proteins. Biol Reprod 65:784-792.
33. Tardif S, Dúbe C, Bailey JL. 2003. Porcine sperm capacitation and tyrosine kinase activity are dependent on bicarbonate and calcium but protein tyrosine phosphorylation is only associated with calcium. Biol Reprod 68:207-213.
34. Taussig R, Gilman AG. 1995. Mammalian membrane-bound adenylyl cyclases. J Biol Chem 270:1-4.
35. Urner F, Sakkas D. 2003. Protein phosphorylation in mammalian spermatozoa. Reproduction 125:17-26.
36. Vijayaraghavan S, Liberty GA, Mohan J, Winfrey VP, Olson GE, Carr DW. 1999. Isolation and molecular characterization of AKAP110, a novel, sperm-specific protein kinase A-anchoring protein. Mol Endocrinol 13:705-717.
37. Visconti PE, Kopf GS. 1998. Regulation of protein phosphorylation during sperm capacitation. Biol Reprod 59:1-6.
38. Visconti PE, Galantino-Homer H, Moore GD, Bailey JL, Ning X, Fornes M, Kopf GS. 1998. The molecular basis of sperm capacitation. J Androl 19:242-248.
39. Visconti PE, Galantino-Homer H, King X, Moore GD, Valenzuela JP, Jorgez CJ, Alvarez JG, Kopf GS. 1999. Cholesterol efflux-mediated signal transduction in mammalian sperm, β-cyclodextrins initiate transmembrane signaling leading to an increase in protein tyrosine phosphorylation and capacitation. J Biol Chem 274:3235-3242.
40. Yanagimachi R. 1994. Mammalian fertilization. In: Knobil E, Neill JD, editors. The physiology of reproduction. 2nd edition. New York: Raven Press, pp 189-317.