Evaluation of the pH effect of formulations on the skin permeability of drugs by biopartitioning micellar chromatography

Journal of Chromatography A

Volumn 1047, Issue 2, 2004, Pages 255-262

  Martinez Pla J J ^a   Martin Biosca Y ^a   Sagrado, S ^a   Villanueva Camanas R M ^a   Medina Hernandez M J ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Biopartitioning micellar chromatography; Micellar liquid chromatography; Non steroidal anti inflammatory drugs; pH effects; Pharmaceutical analysis; Retention permeability relationship

Indexed keywords

DRUG ABSORPTIONS; SKIN PERMEABILITY;

CHROMATOGRAPHIC ANALYSIS; PH EFFECTS; RISK ASSESSMENT;

DRUG PRODUCTS;

ACEMETACIN; DICLOFENAC; FENBUFEN; FENTIAZAC; FLURBIPROFEN; IBUPROFEN; IBUPROXAM; INDOMETACIN; KETOPROFEN; LIDOCAINE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PIKETOPROFEN; SALICYLIC ACID; TOLMETIN;

ANIMAL TISSUE; CONFERENCE PAPER; DRUG FORMULATION; HUMAN; HUMAN TISSUE; MICELLAR LIQUID CHROMATOGRAPHY; MODEL; NONHUMAN; PH; PREDICTION; PRIORITY JOURNAL; RAT; SKIN PERMEABILITY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY, LIQUID; DOSAGE FORMS; HYDROGEN-ION CONCENTRATION; LIDOCAINE; PERMEABILITY; SKIN ABSORPTION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 4444270360     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2004.07.011     Document Type: Conference Paper

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