Long-term effects of 60-Hz electric vs. magnetic fields on IL-1 and IL-2 activity in sheep

Bioelectromagnetics

Volumn 22, Issue 3, 2001, Pages 170-177

  Hefeneider, Steven H ^a,b   McCoy, Sharon L ^a   Hausman, Frances A ^a   Christensen, Heidi L ^a   Takahashi, Diana ^c   Perrin, Nancy ^d   Dan Bracken, T ^e   Shin, K Y ^f   Hall, Arthur S ^g  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON STATE UNIVERSITY   (United States)

^d PORTLAND STATE UNIVERSITY   (United States)

^e T Dan Bracken Incorporated   (United States)

^f Korea Electric Power Research Institute (KEPRI)   (South Korea)

^g OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Cytokines; Extremely low frequency; Immune function; Interleukin 1; Magnetic field

Indexed keywords

ELECTRIC FIELDS; ELECTRIC LINES; ELECTRIC POWER TRANSMISSION; MAGNETIC FIELD EFFECTS; T-CELLS;

% REDUCTIONS; 'CURRENT; CYTOKINES; ELECTRIC AND MAGNETIC FIELDS; EMF EXPOSURE; EXTREMELY LOW FREQUENCIES; IMMUNE FUNCTION; INTERLEUKIN1; MAGNETIC-FIELD; TRANSMISSION-LINE;

ANIMALS;

ANIMALIA; OVIS ARIES;

INTERLEUKIN 1; INTERLEUKIN 2; LIPOPOLYSACCHARIDE;

ANALYSIS OF VARIANCE; ANIMAL; ANIMAL HOUSING; ARTICLE; BLOOD; COMPARATIVE STUDY; DRUG EFFECT; ELECTRICITY; ELECTROMAGNETIC FIELD; ENVIRONMENTAL EXPOSURE; FEMALE; IMMUNOLOGY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; RADIATION EXPOSURE; SHEEP; TIME;

ANALYSIS OF VARIANCE; ANIMALS; ELECTRICITY; ELECTROMAGNETIC FIELDS; ENVIRONMENTAL EXPOSURE; FEMALE; HOUSING, ANIMAL; INTERLEUKIN-1; INTERLEUKIN-2; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; SHEEP; TIME FACTORS;

EID: 0035315817     PISSN: 01978462     EISSN: None     Source Type: Journal    
DOI: 10.1002/bem.35     Document Type: Article

References (22)

1. Adey WR. 1993. Biological effects of electromagnetic fields. J Cell Biochem 51:410-416.
2. Cossarizza A, Angioni S, Petraglia F, Genazzani AR, Monti D, Capri M, Bersani F, Cadossi R, Franceschi C. 1993. Exposure to low frequency pulsed electromagnetic fields increased interleukin-1 and interleukin-6 production by human peripheral blood mononuclear cells. Exp Cell Res 204:385-387.
3. Cossarizza A, Monti D, Bersani F, Cantini M, Cadossi R, Sacchi A, Franceschi C. 1989. Extremely low frequency pulsed electromagnetic fields increase cell proliferation in lymphocytes from young and aged subjects. Biochem Biophys Res Commun 160:692-698.
4. Franceschi C, Cossarizza A, Monti D, Salvioli S, Nuzzo C, Capri M, Scarfi MR, Bersani F. 1991. 50Hz a.c. electric fields affect human lymphocyte proliferation without inducing genotoxic effects. (Abstract) DOE meeting, Milwaukee, WI.
5. Hefeneider SH. 1994. Joint HVAC Transmission EMF Environmental Study: Final Report on Experiment 3. Bonneville Power Administration, Portland, OR.
6. Hefeneider SH, Cornell KA, Brown LE, Bakke AC, McCoy SL, Bennett RM. 1992. Nucleosomes and DNA bind to specific cell-surface molecules on murine cells and induce cytokine production. Clin Immunol Immunopathol 63: 245-251.
7. Hefeneider SH, McCoy SL, Hausman FA. 1998a. Long-term effects of 60Hz electric vs. magnetic fields on IL-1 and other immune parameters in sheep: Phase 4 study. EPRI, Palo Alto, CA. Report TR-111342.
8. Hefeneider SH, McCoy SL, Hausman FA. 1998b. Long-term effects of 60-Hz electric vs. magnetic fields on IL-1 and other immune parameters in sheep: Phase 5 study. EPRI, Palo Alto, CA. Report TR-111343.
9. House RV, Ratajczak HV, Gauger JR, Johnson TR, Thomas PT, McCormick DL. 1996. Immune function and host defense in rodents exposed to 60-Hz magnetic fields. Fundam Appl Toxicol 34:228-239.
10. Jonai H, Villanueva MB, Yasuda A. 1996. Cytokine profile of human peripheral blood mononuclear cells exposed to 50 Hz EMF. Ind Health 34:359-368.
11. Kaye J, Gillis S, Mizeh SD, Sheuach EM, Malek TR, Dinarello CA, Lachman LB, Janeway CA Jr. 1984. Growth of a helper T-cell line induced by a monoclonal antibody specific for the antigen receptor: Interleukin-1 is required for expression of receptors of Interleukin-2. J Immunol 133:1339-1346.
12. Lindstrom E, Lindstrom P, Berglund A, Lundgren E, Mild KH. 1995. Intracellular calcium oscillations in a T-cell line after exposure to extremely-low-frequency magnetic fields with variable frequencies and flux densities. Bioelectromagnetics 16:41-47.
13. Lyle DB, Fuchs TA, Casamento JP, Davis CC, Swicord ML. 1997. Intracellular calcium signaling by Jurkat T-lymphocytes exposed to a 60Hz magnetic field. Bioelectromagnetics 18:439-445.
14. Mevissen M, Haussler M, Szamel M, Emmendorffer A, Thun-Battersby S, Loscher W. 1998. Complex effects of long-term 50 Hz magnetic field exposure in vivo on immune functions in female Sprague-Dawley rats depend on duration of exposure. Bioelectromagnetics 19:259-270.
15. Mevissen M, Lerchl A, Szamel M, Loscher W. 1996. Exposure of DMBA-trealed female rats n a 50-Hz, 50 microTesla magnetic field: effects on mammary tumor growth, melatonin levels, and T lymphocyte activation. Carcinogenesis 17:903-910.
16. Murthy KK, Rogers WR, Smith HD. 1995. Initial studies on the effects of combined 60Hz electric and magnetic field exposure on the immune system of nonhuman primates. Bioelectromagnetics 3 (Suppl.):93-102.
17. Pessina GP, Aldinucci C. 1997. Short cycles of both static and pulsed electromagnetic fields have no effect on the induction of cytokines by peripheral blood mononuclear cells. Bioelectromagnetics 18:548-554.
18. Portier CJ, Wolfe MS, editors. 1998. Assessment of health effects from exposure to power-line frequency electric and magnetic fields. NIEHS Working Report, National Institute of Environmental Health, NIH Publication No. 98-3981.
19. Ramoni C, Dupuis ML, Vecchia P, Polichetti A, Petrini C, Bersani F, Capri M, Cossarizza A, Franceschi C, Grandolfo M. 1995. Human natural killer cytotoxic activity is not affected by in vitro exposure to 50-Hz sinusoidal magnetic fields. Int J Radiat Biol 68:693-705.
20. Stormshak F. 1992. Joint HVAC Transmission EMF Environmental Study, Final Report on Experiment 1. Bonneville Power Administration, Portland, OR.
21. Stormshak F. 1993. Joint HVAC Transmission EMF Environmental Study, Final Report on Experiment 2. Bonneville Power Administration, Portland, OR.
22. Yost MG, Liburdy RP. 1992. Time-varying and static magnetic fields act in combination to alter calcium signal transduction in the lymphocyte. FEBS Lett 296:117-122.