Low blood osteoprotegerin levels are a predictor to poor prognosis in Japanese patients on hemodialysis due to diabetic nephropathy

Therapeutic Apheresis and Dialysis

Volumn 12, Issue 3, 2008, Pages 259-260

  Yokoyama, Keitaro ^a   Shigematsu, Takashi ^b   Miyaki, Koichi ^c   Hara, Shino ^a   Ohkido, Ichiro ^a   Hosoya, Tatsuo ^a   Kono, Takashi ^d   Yoshida, Toyohiko ^d   Muramatsu, Masaaki ^e  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY SCHOOL OF PUBLIC HEALTH   (Japan)

^d Mihama Hospital   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; OSTEOPROTEGERIN; PARATHYROID HORMONE;

ALBUMIN BLOOD LEVEL; DIABETIC NEPHROPATHY; HEMODIALYSIS; HEMOGLOBIN BLOOD LEVEL; HUMAN; JAPANESE; LETTER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL;

ASIAN CONTINENTAL ANCESTRY GROUP; BIOLOGICAL MARKERS; DIABETIC NEPHROPATHIES; FEMALE; HUMANS; JAPAN; MALE; MIDDLE AGED; OSTEOPROTEGERIN; PROGNOSIS; RENAL DIALYSIS;

EID: 44349180771     PISSN: 17449979     EISSN: 17449987     Source Type: Journal    
DOI: 10.1111/j.1744-9987.2008.00583.x     Document Type: Letter

References (8)

1. Lacey DL, Timms E, Tan HL et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998 17 : 165 76.
2. Bucay N, Sarosi I, Dunstan CR et al. osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 1998 12 : 1260 8.
3. Anand DV, Lahiri A, Lim E, Hopkins D, Corder R. The relationship between plasma osteoprotegerin levels and coronary artery calcification in uncomplicated type 2 diabetic subjects. J Am Coll Cardiol 2006 47 : 1850 7.
4. Nitta K, Akiba T, Uchida K et al. Serum osteoprotegerin levels and the extent of vascular calcification in haemodialysis patients. Nephrol Dial Transplant 2004 19 : 1886.
5. Morena M, Terrier N, Jaussent I et al. Plasma osteoprotegerin is associated with mortality in hemodialysis patients. J Am Soc Nephrol 2006 17 : 262 70.
6. Browner WS, Lui LY, Cummings SR. Associations of serum osteoprotegerin levels with diabetes, stroke, bone density, fractures, and mortality in elderly women. J Clin Endocrinol Metab 2001 86 : 631 7.
7. Soufi M, Schoppet M, Sattler AM et al. Osteoprotegerin gene polymorphisms in men with coronary artery disease. J Clin Endocrinol Metab 2004 89 : 3764 8.
8. Vik A, Mathiesen EB, Noto AT, Sveinbjornsson B, Brox J, Hansen JB. Serum osteoprotegerin is inversely associated with carotid plaque echogenicity in humans. Atherosclerosis 2006 18 : 128 34.