Identification of an intronic splicing enhancer essential for the inclusion of FGFR2 exon IIIc

Journal of Biological Chemistry

Volumn 283, Issue 15, 2008, Pages 10058-10067

  Seth, Puneet ^a   Miller, Heather B ^a   Lasda, Erika L ^a,b   Pearson, James L ^a   Garcia Blanco, Mariano A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE SPLICING; CIS ELEMENTS; EPITHELIAL CELLS; FIBROBLAST GROWTH FACTOR RECEPTOR 2; HELA CELLS; IN CELLS; IN VITRO; INTRONIC SPLICING ENHANCERS; LIGAND SPECIFICITIES; MESENCHYMAL CELLS; NUCLEAR EXTRACTS; SPLICE SITES; SPLICING ENHANCERS;

CELL CULTURE; CHEMICAL ACTIVATION; NUCLEIC ACIDS;

BINDING SITES;

BETA GLOBIN; CIS ACTING ELEMENT; ENHANCEOSOME; FIBROBLAST GROWTH FACTOR RECEPTOR 2; INTRONIC ACTIVATOR SEQUENCE 1; INTRONIC SPLICING ENHANCER; LIGAND; NUCLEOTIDE; SMALL NUCLEAR RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG; FGFR2 PROTEIN, HUMAN; FGFR2 PROTEIN, MOUSE; FGFR2 PROTEIN, RAT; GLOBIN;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CELL LINE; EMBRYO; ENHANCER REGION; EXON; GENETIC CONSERVATION; HELA CELL; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; INTRON; MESENCHYME CELL; MOLECULAR PHYLOGENY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RNA BINDING; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; EPITHELIUM; GENETICS; MESODERM; METABOLISM; MOUSE; PHYSIOLOGY;

RATTUS;

ALTERNATIVE SPLICING; ANIMALS; ENHANCER ELEMENTS (GENETICS); EPITHELIUM; EXONS; GLOBINS; HELA CELLS; HUMANS; MESODERM; MICE; ORGAN SPECIFICITY; RATS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR;

EID: 44349169513     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800087200     Document Type: Article

References (33)

1. Black, D. L. (2003) Annu. Rev. Biochem. 72, 291-336
2. Garcia-Blanco, M. A., Baraniak, A. P., and Lasda, E. L. (2004) Nat. Biotechnol. 22, 535-546
3. Matlin, A. J., Clark, F., and Smith, C. W. (2005) Nat. Rev. Mol. Cell. Biol. 6, 386-398
4. Miki, T., Bottaro, D. P., Fleming, T. P., Smith, C. L., Burgess, W. H., Chan, A. M., and Aaronson, S. A. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 246-250
5. Dell, K. R., and Williams, L. T. (1992) J. Biol. Chem. 267, 21225-21229
6. Baraniak, A. P., Chen, J. R., and Garcia-Blanco, M. A. (2006) Mol. Cell. Biol. 26, 1209-1222
7. Carstens, R. P., Wagner, E. J., and Garcia-Blanco, M. A. (2000) Mol. Cell. Biol. 20, 7388-7400
8. Carstens, R. P., McKeehan, W. L., and Garcia-Blanco, M. A. (1998) Mol. Cell. Biol. 18, 2205-2217
9. Wagner, E. J., Baraniak, A. P., Sessions, O. M., Mauger, D., Moskowitz, E., and Garcia-Blanco, M. A. (2005) J. Biol. Chem. 280, 14017-14027
10. Natalizio, B. J., and Garcia-Blanco, M. A. (2005) Methods 37, 314-322
11. Bonano, V., Oltean, S., Brazas, R., and Garcia-Blanco, M. A. (2006) Rna 12, 2073-2079
12. Oltean, S., Sorg, B. S., Albrecht, T., Bonano, V. I., Brazas, R. M., Dewhirst, M. W., and Garcia-Blanco, M. A. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 14116-14121
13. Baraniak, A. P., Lasda, E. L., Wagner, E. J., and Garcia-Blanco, M. A. (2003) Mol. Cell. Biol. 23, 9327-9337
14. Wagner, E. J., Carstens, R. P., and Garcia-Blanco, M. A. (1999) Electrophoresis 20, 1082-1086
15. Merendino, L., Guth, S., Bilbao, D., Martinez, C., and Valcarcel, J. (1999) Nature 402, 838-841
16. Del Gatto, F., and Breathnach, R. (1995) Genomics 27, 558-559
17. Mistry, N., Harrington, W., Lasda, E., Wagner, E. J., and Garcia-Blanco, M. A. (2003) Rna 9, 209-217
18. Del Gatto, F., and Breathnach, R. (1995) Mol. Cell. Biol. 15, 4825-4834
19. Del Gatto, F., Plet, A., Gesnel, M. C., Fort, C., and Breathnach, R. (1997) Mol. Cell. Biol. 17, 5106-5116
20. Del Gatto-Konczak, F., Bourgeois, C. F., Le Guiner, C., Kister, L., Gesnel, M. C., Stevenin, J., and Breathnach, R. (2000) Mol. Cell. Biol. 20, 6287-6299
21. Le Guiner, C., Gesnel, M. C., and Breathnach, R. (2003) J. Biol. Chem. 278, 10465-10476
22. Campbell, R. E., Tour, O., Palmer, A. E., Steinbach, P. A., Baird, G. S., Zacharias, D. A., and Tsien, R. Y. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 7877-7882
23. Goldstrohm, A. C., Greenleaf, A. L., and Garcia-Blanco, M. A. (2001) Gene (Amst.) 277, 31-47
24. Black, D. L. (1992) Cell 69, 795-807
25. Blencowe, B. J. (2000) Trends Biochem. Sci. 25, 106-110
26. Oldridge, M., Zackai, E. H., McDonald-McGinn, D. M., Iseki, S., Morriss-Kay, G. M., Twigg, S. R., Johnson, D., Wall, S. A., Jiang, W., Theda, C., Jabs, E. W., and Wilkie, A. O. (1999) Am. J. Hum. Genet. 64, 446-461
27. Ule, J., Stefani, G., Mele, A., Ruggiu, M., Wang, X., Taneri, B., Gaasterland, T., Blencowe, B. J., and Darnell, R. B. (2006) Nature 30, 580-586
28. Carlo, T., Sterner, D. A., and Berget, S. M. (1996) Rna 2, 342-353
29. Del Gatto, F., Gesnel, M. C., and Breathnach, R. (1996) Nucleic Acids Res. 24, 2017-2021
30. Wagner, E. J., and Garcia-Blanco, M. A. (2002) Mol Cell 10, 943-949
31. Le Guiner, C., Lejeune, F., Galiana, D., Kister, L., Breathnach, R., Stevenin, J., and Del Gatto-Konczak, F. (2001) J. Biol. Chem. 276, 40638-40646
32. Han, K., Yeo, G., An, P., Burge, C. B., and Grabowski, P. J. (2005) PLoS Biol. 3, e158
33. Fededa, J. P., Petrillo, E., Gelfand, M. S., Neverov, A. D., Kadener, S., Nogues, G., Pelisch, F., Baralle, F. E., Muro, A. F., and Kornblihtt, A. R. (2005) Mol. Cell 19, 393-404