Role of cAMP-responsive element modulator-τ (CREMτ) in ipsilateral testicular injury after unilateral testicular torsion-detorsion

Fertility and Sterility

Volumn 89, Issue 6, 2008, Pages 1737-1742

  Wei, Si Ming ^a,c   Yan, Zhi Zhong ^b   Zhou, Jian ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b HANGZHOU RED CROSS HOSPITAL   (China)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

cAMP responsive element modulator (CREM ); spermatogenesis; Testicular torsion

Indexed keywords

CAMP RESPONSIVE ELEMENT MODULATOR TAU; CYCLIC AMP; MESSENGER RNA; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CONTROL GROUP; CONTROLLED STUDY; EXPERIMENTAL STUDY; GERM CELL; MALE; NONHUMAN; ORCHIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINIFEROUS TUBULE; SHAM PROCEDURE; SPERMATOGENESIS; TESTIS; TESTIS BIOPSY; TESTIS INJURY; TESTIS TORSION; TESTIS WEIGHT; WESTERN BLOTTING;

ANIMALS; CYCLIC AMP RESPONSE ELEMENT MODULATOR; DISEASE MODELS, ANIMAL; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; MALE; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPERMATIC CORD TORSION; SPERMATOGENESIS; TESTIS;

EID: 44349126207     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.04.044     Document Type: Article

References (31)

1. Barada J.H., Weingarten J.L., and Cromie W.J. Testicular salvage and age-related delay in the presentation of testicular torsion. J Urol 142 (1989) 746-748
2. Parker R.M., and Robison J.R. Anatomy and diagnosis of torsion of the testicle. J Urol 106 (1971) 243-247
3. Cattolica E.V., Karol J.B., Rankin K.N., and Klein R.S. High testicular salvage rate in torsion of the spermatic cord. J Urol 128 (1982) 66-68
4. Macnicol M.F. Torsion of the testis in childhood. Br J Surg 61 (1974) 905-908
5. Krarup T. The testes after torsion. Br J Urol 50 (1978) 43-46
6. Ozturk H., Ozturk H., and Yagmur Y. PAF antagonist BN-52021 reduces intercellular adhesion molecule-1 expression and oxidative stress in rats with reperfusion damage due to unilateral testicular torsion. Pediatr Surg Int 22 (2006) 191-196
7. Cay A., Alver A., Kucuk M., Isik O., Eminagaoglu M.S., Karahan S.C., et al. The effects of N-acetylcysteine on antioxidant enzyme activities in experimental testicular torsion. J Surg Res 131 (2006) 199-203
8. Sassone-Corsi P. Transcription factors responsive to cAMP. Ann Rev Cell Dev Biol 11 (1995) 355-377
9. Fimia G.M., De Cesare D., and Sassone-Corsi P. CBP-independent activation of CREM and CREB by the LIM-only protein ACT. Nature 398 (1999) 165-169
10. Foulkes N.S., Mellstrom B., Benusiglio E., and Sassone-Corsi P. Developmental switch of CREM function during spermatogenesis: from antagonist to activator. Nature 355 (1992) 80-84
11. Foulkes N.S., Borrelli E., and Sassone-Corsi P. CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription. Cell 64 (1991) 739-749
12. Zhou Y., Sun Z., Means A.R., Sassone-Corsi P., and Bernstein K.E. cAMP-response element modulator tau is a positive regulator of testis angiotensin converting enzyme transcription. Proc Natl Acad Sci USA 93 (1996) 12262-12266
13. Nantel F., Monaco L., Foulkes N.S., Masquilier D., LeMeur M., Henriksen K., et al. Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice. Nature 380 (1996) 159-162
14. Blendy J.A., Kaestner K.H., Weinbauer G.F., Nieschlag E., and Schutz G. Severe impairment of spermatogenesis in mice lacking the CREM gene. Nature 380 (1996) 162-165
15. Johnsen S.G. Testicular biopsy score count-a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. Hormones 1 (1970) 2-25
16. Anderson J.B., and Williamson R.C. The fate of the human testes following unilateral torsion of the spermatic cord. Br J Urol 58 (1986) 698-704
17. Williamson R.C. The continuing conundrum of testicular torsion. Br J Surg 72 (1985) 509-510
18. Gonzalez G.A., Yamamoto K.K., Fischer W.H., Karr D., Menzel P., Biggs III W., et al. A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence. Nature 337 (1989) 749-752
19. Foulkes N.S., Schlotter F., Pevet P., and Sassone-Corsi P. Pituitary hormone FSH directs the CREM functional switch during spermatogenesis. Nature 362 (1993) 264-267
20. Walker W.H., Sanborn B.M., and Habener J.F. An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription. Proc Natl Acad Sci USA 91 (1994) 12423-12427
21. Sassone-Corsi P. CREM: a master-switch governing male germ cells differentiation and apoptosis. Semin Cell Dev Biol 9 (1998) 475-482
22. De cesare D., Fimia G.M., and Sassone-Corsi P. Signaling routes to CREM and CREB: plasticity in transcriptional activation. Trends Biochem Sci 24 (1999) 281-285
23. Parvinen M. Regulation of the seminiferous epithelium. Endocrinol Rev 3 (1982) 404-417
24. Behr R., and Weinbauer G.F. cAMP response element modulator (CREM): an essential factor for spermatogenesis in primates?. Int J Androl 24 (2001) 126-135
25. Uguralp S., Bay Karabulut A., Mizrak B., Kaymaz F., Kiziltay A., and Hasirci N. The effect of sustained and local administration of epidermal growth factor on improving bilateral testicular tissue after torsion. Urol Res 32 (2004) 323-331
26. Rodriguez M.G., Rival C., Theas M.S., and Lustig L. Immunohistopathology of the contralateral testis of rats undergoing experimental torsion of the spermatic cord. Asian J Androl 8 (2006) 576-583
27. Tunckiran A., Cayan S., Bozlu M., Yilmaz N., Acar D., and Akbay E. Protective effect of vascular endothelial growth factor on histologic changes in testicular ischemia-reperfusion injury. Fertil Steril 84 (2005) 468-473
28. Salmasi A.H., Beheshtian A., Payabvash S., Demehri S., Ebrahimkhani M.R., Karimzadegan M., et al. Effect of morphine on ischemia-reperfusion injury: experimental study in testicular torsion rat model. Urology 66 (2005) 1338-1342
29. Turner T.T., and Brown K.J. Spermatic cord torsion: loss of spermatogenesis despite return of blood flow. Biol Reprod 49 (1993) 401-407
30. Somuncu S., Cakmak M., Erdogan S., Caglayan O., Akman H., and Kaya M. Protective effects of trapidil in ischemia-reperfusion injury due to testicular torsion and detorsion: an experimental study. Int J Urol 13 (2006) 601-605
31. Tien Kuo M., and Savaraj N. Roles of reactive oxygen species in hepatocarcinogenesis and drug resistance gene expression in liver cancers. Mol Carcinog 45 (2006) 701-709