메뉴 건너뛰기




Volumn 121, Issue 6 SUPPL., 2008, Pages

Initiating and Intensifying Insulin Therapy in Type 2 Diabetes Mellitus

Author keywords

Basal Insulin; Insulin; Insulin Initiation; Insulin Intensification; Premix Insulin; Type 2 Diabetes Mellitus

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALPHA GLUCOSIDASE INHIBITOR; EXENDIN 4; HUMAN INSULIN; INSULIN ASPART; INSULIN DERIVATIVE; INSULIN DETEMIR; INSULIN GLARGINE; ISOPHANE INSULIN; MEGLITINIDE; METFORMIN; ORAL ANTIDIABETIC AGENT; SULFONYLUREA;

EID: 44249109983     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjmed.2008.03.023     Document Type: Article
Times cited : (17)

References (53)
  • 2
    • 0003191725 scopus 로고    scopus 로고
    • American College of Endocrinology Consensus Statement on Guidelines for Glycemic Control, 2001
    • Available at: http://www.aace.com/meetings/consensus/dcc/pdf/dccwhitepaper.pdf. Accessed March 14, 2007
    • American College of Endocrinology Consensus Statement on Guidelines for Glycemic Control, 2001. Endocr Pract. 8 suppl 1 (2002) 5-11. http://www.aace.com/meetings/consensus/dcc/pdf/dccwhitepaper.pdf Available at: http://www.aace.com/meetings/consensus/dcc/pdf/dccwhitepaper.pdf. Accessed March 14, 2007
    • (2002) Endocr Pract. , vol.8 , Issue.SUPPL. 1 , pp. 5-11
  • 3
    • 33845996154 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2007
    • American Diabetes Association
    • American Diabetes Association. Standards of medical care in diabetes-2007. Diabetes Care 30 suppl1 (2007) S4-S41
    • (2007) Diabetes Care , vol.30 , Issue.suppl1
  • 4
    • 34447535582 scopus 로고    scopus 로고
    • Road maps to achieve glycemic control in type 2 diabetes mellitus [ACE/AACE Diabetes Recommendations Implementation Conference; AACE Website]
    • ACE/AACE Diabetes Road Map Task Force, 2007 Available at: http://www.aace.com/meetings/consensus/odimplementation/roadmap.pdf. Accessed April 17, 2007
    • ACE/AACE Diabetes Road Map Task Force, 2007. Road maps to achieve glycemic control in type 2 diabetes mellitus [ACE/AACE Diabetes Recommendations Implementation Conference; AACE Website]. Endocr Pract. 13 (2007) 260-268. http://www.aace.com/meetings/consensus/odimplementation/roadmap.pdf Available at: http://www.aace.com/meetings/consensus/odimplementation/roadmap.pdf. Accessed April 17, 2007
    • (2007) Endocr Pract. , vol.13 , pp. 260-268
  • 5
    • 33644798145 scopus 로고    scopus 로고
    • Resistance to insulin therapy among patients and providers: results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study
    • International DAWN Advisory Panel
    • Peyrot M., Rubin R.R., Lauritzen T., et al., International DAWN Advisory Panel. Resistance to insulin therapy among patients and providers: results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study. Diabetes Care 28 (2005) 2673-2679
    • (2005) Diabetes Care , vol.28 , pp. 2673-2679
    • Peyrot, M.1    Rubin, R.R.2    Lauritzen, T.3
  • 6
    • 0036736185 scopus 로고    scopus 로고
    • When oral agents fail: practical barriers to starting insulin
    • Korytkowski M. When oral agents fail: practical barriers to starting insulin. Int J Obes Relat Metab Disord. 26 suppl 3 (2002) S18-S24
    • (2002) Int J Obes Relat Metab Disord. , vol.26 , Issue.SUPPL. 3
    • Korytkowski, M.1
  • 7
    • 0028817815 scopus 로고
    • Overview of 6 years' therapy of type 2 diabetes: a progressive disease
    • UK Prospective Diabetes Study Group 16
    • UK Prospective Diabetes Study Group 16. Overview of 6 years' therapy of type 2 diabetes: a progressive disease. Diabetesz 44 (1995) 1249-1258
    • (1995) Diabetesz , vol.44 , pp. 1249-1258
  • 8
    • 33845405222 scopus 로고    scopus 로고
    • Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
    • ADOPT Study Group. [published correction appears in N Engl J Med. 2007;356:1387-1388]
    • Kahn S.E., Haffner S.M., Heise M.A., et al., ADOPT Study Group. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. [published correction appears in N Engl J Med. 2007;356:1387-1388]. N Engl J Med. 355 (2006) 2427-2443
    • (2006) N Engl J Med. , vol.355 , pp. 2427-2443
    • Kahn, S.E.1    Haffner, S.M.2    Heise, M.A.3
  • 9
    • 0035663189 scopus 로고    scopus 로고
    • Beneficial effects of intensive therapy of diabetes during adolescence: outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT)
    • Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group
    • White N.H., Cleary P.A., Dahms W., Goldstein D., Malone J., Tamborlane W.V., and Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group. Beneficial effects of intensive therapy of diabetes during adolescence: outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT). J Pediatr. 139 (2001) 804-812
    • (2001) J Pediatr. , vol.139 , pp. 804-812
    • White, N.H.1    Cleary, P.A.2    Dahms, W.3    Goldstein, D.4    Malone, J.5    Tamborlane, W.V.6
  • 10
    • 0037093012 scopus 로고    scopus 로고
    • Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus
    • Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group 287
    • Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus. JAMA 15 (2002) 2563-2569 287
    • (2002) JAMA , vol.15 , pp. 2563-2569
  • 11
    • 0142087597 scopus 로고    scopus 로고
    • Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study
    • Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group
    • Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study. JAMA 290 (2003) 2159-2167
    • (2003) JAMA , vol.290 , pp. 2159-2167
  • 12
    • 0034641568 scopus 로고    scopus 로고
    • Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS35): prospective observational study
    • Stratton I.M., Adler A.I., Neil H.A., et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS35): prospective observational study. BMJ 321 (2000) 405-412
    • (2000) BMJ , vol.321 , pp. 405-412
    • Stratton, I.M.1    Adler, A.I.2    Neil, H.A.3
  • 13
    • 33750938876 scopus 로고    scopus 로고
    • Meta-analysis: efficacy and safety of inhaled insulin therapy in adults with diabetes mellitus
    • Ceglia L., Lau J., and Pittas A.G. Meta-analysis: efficacy and safety of inhaled insulin therapy in adults with diabetes mellitus. Ann Intern Med. 145 (2006) 665-675
    • (2006) Ann Intern Med. , vol.145 , pp. 665-675
    • Ceglia, L.1    Lau, J.2    Pittas, A.G.3
  • 14
    • 0242269000 scopus 로고    scopus 로고
    • The Treat-to-Target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients
    • Insulin Glargine 4002 Study Investigators
    • Riddle M.C., Rosenstock J., Gerich J., and Insulin Glargine 4002 Study Investigators. The Treat-to-Target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 26 (2003) 3080-3086
    • (2003) Diabetes Care , vol.26 , pp. 3080-3086
    • Riddle, M.C.1    Rosenstock, J.2    Gerich, J.3
  • 15
    • 33845236398 scopus 로고    scopus 로고
    • Comparison of once-daily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly controlled type 2 diabetes
    • Philis-Tsimikas A., Charpentier G., Clauson P., Ravn G.M., Roberts V.L., and Thorsteinsson B. Comparison of once-daily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly controlled type 2 diabetes. Clin Ther. 28 (2006) 1569-1581
    • (2006) Clin Ther. , vol.28 , pp. 1569-1581
    • Philis-Tsimikas, A.1    Charpentier, G.2    Clauson, P.3    Ravn, G.M.4    Roberts, V.L.5    Thorsteinsson, B.6
  • 16
    • 33746391488 scopus 로고    scopus 로고
    • A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naïve people with type 2 diabetes
    • Hermansen K., Davies M., Derezinski T., Martinez Ravn G., Clauson P., and Home P. A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naïve people with type 2 diabetes. Diabetes Care 29 (2006) 1269-1274
    • (2006) Diabetes Care , vol.29 , pp. 1269-1274
    • Hermansen, K.1    Davies, M.2    Derezinski, T.3    Martinez Ravn, G.4    Clauson, P.5    Home, P.6
  • 17
    • 0031878264 scopus 로고    scopus 로고
    • Assessment by patients with diabetes mellitus of two insulin pen delivery systems versus a vial and syringe
    • Graff M.R., and McClanahan M.A. Assessment by patients with diabetes mellitus of two insulin pen delivery systems versus a vial and syringe. Clin Ther. 20 (1998) 486-496
    • (1998) Clin Ther. , vol.20 , pp. 486-496
    • Graff, M.R.1    McClanahan, M.A.2
  • 18
    • 9644260875 scopus 로고    scopus 로고
    • Preference for insulin delivery systems among current insulin users and nonusers
    • Summers K.H., Szeinbach S.L., and Lenox S.M. Preference for insulin delivery systems among current insulin users and nonusers. Clin Ther. 26 (2004) 1498-1505
    • (2004) Clin Ther. , vol.26 , pp. 1498-1505
    • Summers, K.H.1    Szeinbach, S.L.2    Lenox, S.M.3
  • 19
    • 33745238058 scopus 로고    scopus 로고
    • A review of 20 years' experience with the NovoPen family of insulin injection devices
    • Rex J., Jensen K.H., and Lawton S.A. A review of 20 years' experience with the NovoPen family of insulin injection devices. Clin Drug Investig. 26 (2006) 367-401
    • (2006) Clin Drug Investig. , vol.26 , pp. 367-401
    • Rex, J.1    Jensen, K.H.2    Lawton, S.A.3
  • 20
    • 33646008588 scopus 로고    scopus 로고
    • Biphasic insulin aspart 30 plus metformin: an effective combination in type 2 diabetes
    • Kvapil M., Swatko A., Hilberg C., and Shestakova M. Biphasic insulin aspart 30 plus metformin: an effective combination in type 2 diabetes. Diabetes Obes Metab 8 (2006) 39-48
    • (2006) Diabetes Obes Metab , vol.8 , pp. 39-48
    • Kvapil, M.1    Swatko, A.2    Hilberg, C.3    Shestakova, M.4
  • 21
    • 33751010734 scopus 로고    scopus 로고
    • Thiazolidinediones in patients with diabetes mellitus and heart failure: implications of emerging data
    • Macfarlane D.P., and Fisher M. Thiazolidinediones in patients with diabetes mellitus and heart failure: implications of emerging data. Am J Cardiovasc Drugs 6 (2006) 297-304
    • (2006) Am J Cardiovasc Drugs , vol.6 , pp. 297-304
    • Macfarlane, D.P.1    Fisher, M.2
  • 22
    • 33646254423 scopus 로고    scopus 로고
    • Once-daily insulin glargine administration in the morning compared to bedtime in combination with morning glimepiride in patients with type 2 diabetes: an assessment of treatment flexibility
    • HOE901/4009 Study Group
    • Standl E., Maxeiner S., Raptis S., and HOE901/4009 Study Group. Once-daily insulin glargine administration in the morning compared to bedtime in combination with morning glimepiride in patients with type 2 diabetes: an assessment of treatment flexibility. Horm Metab Res. 38 (2006) 172-177
    • (2006) Horm Metab Res. , vol.38 , pp. 172-177
    • Standl, E.1    Maxeiner, S.2    Raptis, S.3
  • 23
    • 33646414185 scopus 로고    scopus 로고
    • Therapy in type 2 diabetes: insulin glargine vs. NPH insulin both in combination with glimepiride
    • HOE 901/4013 LA Study Group
    • Eliaschewitz F.G., Calvo C., Valbuena H., et al., HOE 901/4013 LA Study Group. Therapy in type 2 diabetes: insulin glargine vs. NPH insulin both in combination with glimepiride. Arch Med Res. 37 (2006) 495-501
    • (2006) Arch Med Res. , vol.37 , pp. 495-501
    • Eliaschewitz, F.G.1    Calvo, C.2    Valbuena, H.3
  • 24
    • 33646014162 scopus 로고    scopus 로고
    • Attainment of glycaemic goals in type 2 diabetes with once-, twice-, or thrice-daily dosing with biphasic insulin aspart 70/30 (The 1-2-3 Study)
    • Garber A.J., Wahlen J., Wahl T., et al. Attainment of glycaemic goals in type 2 diabetes with once-, twice-, or thrice-daily dosing with biphasic insulin aspart 70/30 (The 1-2-3 Study). Diabetes Obes Metab. 8 (2006) 58-66
    • (2006) Diabetes Obes Metab. , vol.8 , pp. 58-66
    • Garber, A.J.1    Wahlen, J.2    Wahl, T.3
  • 25
    • 12844265257 scopus 로고    scopus 로고
    • Initiating insulin therapy in type 2 diabetes: a comparison of biphasic and basal insulin analogs
    • INITIATE study group
    • Raskin P., Allen E., Hollander P., et al., INITIATE study group. Initiating insulin therapy in type 2 diabetes: a comparison of biphasic and basal insulin analogs. Diabetes Care 28 (2005) 260-265
    • (2005) Diabetes Care , vol.28 , pp. 260-265
    • Raskin, P.1    Allen, E.2    Hollander, P.3
  • 26
    • 14844360413 scopus 로고    scopus 로고
    • Combined therapy with insulin lispro Mix 75/25 plus metformin or insulin glargine plus metformin: a 16-week, randomized, open-label, crossover study in patients with type 2 diabetes beginning insulin therapy
    • Lispro Mixture-Glargine Study Group. [published correction appears in Clin Ther. 2005;27:1112]
    • Malone J.K., Kerr L.F., Campaigne B.N., et al., Lispro Mixture-Glargine Study Group. Combined therapy with insulin lispro Mix 75/25 plus metformin or insulin glargine plus metformin: a 16-week, randomized, open-label, crossover study in patients with type 2 diabetes beginning insulin therapy. [published correction appears in Clin Ther. 2005;27:1112]. Clin Ther. 26 (2004) 2034-2044
    • (2004) Clin Ther. , vol.26 , pp. 2034-2044
    • Malone, J.K.1    Kerr, L.F.2    Campaigne, B.N.3
  • 27
    • 34247144471 scopus 로고    scopus 로고
    • Therapeutic effectiveness of two insulin regimens for insulin naive patients with type 2 diabetes mellitus: once-daily basal insulin or twice-daily premixed insulin?
    • Abstract 427-P
    • Sun P., Wang R., and Jacober S.J. Therapeutic effectiveness of two insulin regimens for insulin naive patients with type 2 diabetes mellitus: once-daily basal insulin or twice-daily premixed insulin?. Diabetes 55 suppl 1 (2006) Abstract 427-P
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Sun, P.1    Wang, R.2    Jacober, S.J.3
  • 28
    • 17144389381 scopus 로고    scopus 로고
    • Twice-daily pre-mixed insulin rather than basal insulin therapy alone results in better overall glycaemic control in patients with Type 2 diabetes
    • Malone J.K., Bai S., Campaigne B.N., Reviriego J., and Augendre-Ferrante B. Twice-daily pre-mixed insulin rather than basal insulin therapy alone results in better overall glycaemic control in patients with Type 2 diabetes. Diabet Med. 22 (2005) 374-381
    • (2005) Diabet Med. , vol.22 , pp. 374-381
    • Malone, J.K.1    Bai, S.2    Campaigne, B.N.3    Reviriego, J.4    Augendre-Ferrante, B.5
  • 29
    • 6344228105 scopus 로고    scopus 로고
    • The pathophysiological basis for intensive insulin replacement
    • Rolla A. The pathophysiological basis for intensive insulin replacement. Int J Obes Relat Metab Disord. 28 suppl 2 (2004) S3-S7
    • (2004) Int J Obes Relat Metab Disord. , vol.28 , Issue.SUPPL. 2
    • Rolla, A.1
  • 30
    • 12244284000 scopus 로고    scopus 로고
    • Beta- and alpha-cell dysfunction in type 2 diabetes
    • Del Prato S., and Marchetti P. Beta- and alpha-cell dysfunction in type 2 diabetes. Horm Metab Res. 36 (2004) 775-781
    • (2004) Horm Metab Res. , vol.36 , pp. 775-781
    • Del Prato, S.1    Marchetti, P.2
  • 31
    • 33847409390 scopus 로고    scopus 로고
    • The role of glucose as an independent cardiovascular risk factor
    • Middelbeek R.J., and Horton E.S. The role of glucose as an independent cardiovascular risk factor. Curr Diab Rep. 7 (2007) 43-49
    • (2007) Curr Diab Rep. , vol.7 , pp. 43-49
    • Middelbeek, R.J.1    Horton, E.S.2
  • 32
    • 33646569958 scopus 로고    scopus 로고
    • Contributions of fasting and postprandial glucose to hemoglobin A1c
    • Monnier L., Colette C., Monnier L., and Colette C. Contributions of fasting and postprandial glucose to hemoglobin A1c. Endocr Pract. 12 suppl 1 (2006) 42-46
    • (2006) Endocr Pract. , vol.12 , Issue.SUPPL. 1 , pp. 42-46
    • Monnier, L.1    Colette, C.2    Monnier, L.3    Colette, C.4
  • 33
    • 34247149764 scopus 로고    scopus 로고
    • A review of human and analogue insulin trials
    • Gough S.C. A review of human and analogue insulin trials. Diabetes Res Clin Pract. 77 (2007) 1-15
    • (2007) Diabetes Res Clin Pract. , vol.77 , pp. 1-15
    • Gough, S.C.1
  • 34
    • 0034609223 scopus 로고    scopus 로고
    • Insulin glargine
    • Bolli G.B., and Owens D.R. Insulin glargine. Lancet 356 (2000) 443-445
    • (2000) Lancet , vol.356 , pp. 443-445
    • Bolli, G.B.1    Owens, D.R.2
  • 35
    • 4344701890 scopus 로고    scopus 로고
    • The mechanism of protraction of insulin detemir, a long-acting, acylated analog of human insulin
    • Havelund S., Plum A., Ribel U., et al. The mechanism of protraction of insulin detemir, a long-acting, acylated analog of human insulin. Pharm Res. 21 (2004) 1498-1504
    • (2004) Pharm Res. , vol.21 , pp. 1498-1504
    • Havelund, S.1    Plum, A.2    Ribel, U.3
  • 36
    • 33947644300 scopus 로고    scopus 로고
    • Albumin-bound basal insulin analogues (insulin detemir and NN344): comparable time-action profiles but less variability than insulin glargine in type 2 diabetes
    • Klein O., Lynge J., Endahl L., Damholt B., Nosek L., and Heise T. Albumin-bound basal insulin analogues (insulin detemir and NN344): comparable time-action profiles but less variability than insulin glargine in type 2 diabetes. Diabetes Obes Metab. 9 (2007) 290-299
    • (2007) Diabetes Obes Metab. , vol.9 , pp. 290-299
    • Klein, O.1    Lynge, J.2    Endahl, L.3    Damholt, B.4    Nosek, L.5    Heise, T.6
  • 37
    • 0038131919 scopus 로고    scopus 로고
    • Glimepiride combined with morning insulin glargine, bedtime neutral protamine Hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes: a randomized, controlled trial
    • 4001 Study Group
    • Fritsche A., Schweitzer M.A., Haring H.U., and 4001 Study Group. Glimepiride combined with morning insulin glargine, bedtime neutral protamine Hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes: a randomized, controlled trial. Ann Intern Med. 138 (2003) 952-959
    • (2003) Ann Intern Med. , vol.138 , pp. 952-959
    • Fritsche, A.1    Schweitzer, M.A.2    Haring, H.U.3
  • 38
    • 0038292180 scopus 로고    scopus 로고
    • A one-year, randomised, multicentre trial comparing insulin glargine with NPH insulin in combination with oral agents in patients with type 2 diabetes
    • Massi Benedetti M., Humburg E., Dressler A., and Ziemen M. A one-year, randomised, multicentre trial comparing insulin glargine with NPH insulin in combination with oral agents in patients with type 2 diabetes. Horm Metab Res. 35 (2003) 189-196
    • (2003) Horm Metab Res. , vol.35 , pp. 189-196
    • Massi Benedetti, M.1    Humburg, E.2    Dressler, A.3    Ziemen, M.4
  • 39
    • 33644873468 scopus 로고    scopus 로고
    • 1c on glycemic control in patients with type 2 diabetes: the Glycemic Optimization with Algorithms and Labs at Point of Care (GOAL A1C) trial
    • GOAL A1C Team
    • 1c on glycemic control in patients with type 2 diabetes: the Glycemic Optimization with Algorithms and Labs at Point of Care (GOAL A1C) trial. Diabetes Care 29 (2006) 1-8
    • (2006) Diabetes Care , vol.29 , pp. 1-8
    • Kennedy, L.1    Herman, W.H.2    Strange, P.3    Harris, A.4
  • 40
    • 33244479164 scopus 로고    scopus 로고
    • Insulin glargine or NPH combined with metformin in type 2 diabetes: the LANMET study
    • Yki-Jarvinen H., Kauppinen-Makelin R., et al. Insulin glargine or NPH combined with metformin in type 2 diabetes: the LANMET study. Diabetologia 49 (2006) 442-451
    • (2006) Diabetologia , vol.49 , pp. 442-451
    • Yki-Jarvinen, H.1    Kauppinen-Makelin, R.2
  • 41
    • 33947302393 scopus 로고    scopus 로고
    • Insulin detemir results in less weight gain than NPH insulin when used in basal-bolus therapy for type 2 diabetes, and this advantage increases with baseline body mass index
    • Rašlová K., Tamer S.C., Clauson P., and Karl D. Insulin detemir results in less weight gain than NPH insulin when used in basal-bolus therapy for type 2 diabetes, and this advantage increases with baseline body mass index. Clin Drug Investig. 27 (2007) 279-285
    • (2007) Clin Drug Investig. , vol.27 , pp. 279-285
    • Rašlová, K.1    Tamer, S.C.2    Clauson, P.3    Karl, D.4
  • 42
    • 33947636649 scopus 로고    scopus 로고
    • Insulin detemir improves glycaemic control with less hypoglycaemia and no weight gain in patients with type 2 diabetes who were insulin naïve or treated with NPH or insulin glargine: clinical practice experience from a German subgroup of the PREDICTIVE study
    • Meneghini L.F., Rosenberg K.H., Koenen C., Merilainen M.J., and Luddeke H.J. Insulin detemir improves glycaemic control with less hypoglycaemia and no weight gain in patients with type 2 diabetes who were insulin naïve or treated with NPH or insulin glargine: clinical practice experience from a German subgroup of the PREDICTIVE study. Diabetes Obes Metab. 9 (2007) 418-427
    • (2007) Diabetes Obes Metab. , vol.9 , pp. 418-427
    • Meneghini, L.F.1    Rosenberg, K.H.2    Koenen, C.3    Merilainen, M.J.4    Luddeke, H.J.5
  • 43
    • 19944368427 scopus 로고    scopus 로고
    • Improvement of glycemic control in subjects with poorly controlled type 2 diabetes: comparison of two treatment algorithms using insulin glargine
    • ATLANTUS Study Group
    • Davies M., Storms F., Shutler S., et al., ATLANTUS Study Group. Improvement of glycemic control in subjects with poorly controlled type 2 diabetes: comparison of two treatment algorithms using insulin glargine. Diabetes Care 28 (2005) 1282-1288
    • (2005) Diabetes Care , vol.28 , pp. 1282-1288
    • Davies, M.1    Storms, F.2    Shutler, S.3
  • 44
    • 0142138134 scopus 로고    scopus 로고
    • Starting patients with type 2 diabetes on insulin therapy using once-daily injections of biphasic insulin aspart 70/30, biphasic human insulin 70/30, or NPH insulin in combination with metformin
    • Kilo C., Mezitis N., Jain R., Mersey J., McGill J., and Raskin P. Starting patients with type 2 diabetes on insulin therapy using once-daily injections of biphasic insulin aspart 70/30, biphasic human insulin 70/30, or NPH insulin in combination with metformin. J Diabetes Complications 17 (2003) 307-313
    • (2003) J Diabetes Complications , vol.17 , pp. 307-313
    • Kilo, C.1    Mezitis, N.2    Jain, R.3    Mersey, J.4    McGill, J.5    Raskin, P.6
  • 45
    • 33646554847 scopus 로고    scopus 로고
    • Comparative efficacy of glimepiride and/or metformin with insulin in type 2 diabetes
    • Kabadi U.M., and Kabadi M. Comparative efficacy of glimepiride and/or metformin with insulin in type 2 diabetes. Diabetes Res Clin Pract. 72 (2006) 265-270
    • (2006) Diabetes Res Clin Pract. , vol.72 , pp. 265-270
    • Kabadi, U.M.1    Kabadi, M.2
  • 46
    • 34248998816 scopus 로고    scopus 로고
    • ® Mix 70/30 once or twice daily is more efficacious than optimizing oral treatment in patients with type 2 diabetes
    • BIAsp-3021 Study Group. [abstract]
    • ® Mix 70/30 once or twice daily is more efficacious than optimizing oral treatment in patients with type 2 diabetes. [abstract]. Diabetes 54 suppl 1 (2005) A510
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 1
    • Wan, M.W.1
  • 47
    • 44249121168 scopus 로고    scopus 로고
    • 1c <7% by adding biphasic insulin aspart 30 to optimized metformin and pioglitazone treatment
    • [abstract 803]
    • 1c <7% by adding biphasic insulin aspart 30 to optimized metformin and pioglitazone treatment. Diabetologia 49 suppl 1 (2006) 487 [abstract 803]
    • (2006) Diabetologia , vol.49 , Issue.SUPPL. 1 , pp. 487
    • Raskin, P.1    Braceras, R.2    Schwartz, S.3    Chaykin, L.4    Chu, P.-L.5    Wynne, A.6
  • 48
    • 34248167537 scopus 로고    scopus 로고
    • Insulin as initial therapy in type 2 diabetes: effective, safe, and well accepted
    • Lingvay I., Kaloyanova P.F., Adams-Huet B., Salinas K., and Raskin P. Insulin as initial therapy in type 2 diabetes: effective, safe, and well accepted. J Investig Med. 55 (2007) 62-68
    • (2007) J Investig Med. , vol.55 , pp. 62-68
    • Lingvay, I.1    Kaloyanova, P.F.2    Adams-Huet, B.3    Salinas, K.4    Raskin, P.5
  • 49
    • 41749096171 scopus 로고    scopus 로고
    • Biphasic insulin aspart 70/30 three times a day in older patients with Type 2 diabetes not achieving optimal glycemic control on a twice-daily regimen: A retrospective case series analysis from clinical practice
    • Tibaldi J. Biphasic insulin aspart 70/30 three times a day in older patients with Type 2 diabetes not achieving optimal glycemic control on a twice-daily regimen: A retrospective case series analysis from clinical practice. Adv Ther 24 (2007) 1348-1356
    • (2007) Adv Ther , Issue.24 , pp. 1348-1356
    • Tibaldi, J.1
  • 50
    • 33646508084 scopus 로고    scopus 로고
    • Comparison of the pharmacokinetics and pharmacodynamics of biphasic insulin aspart and insulin glargine in people with type 2 diabetes
    • Luzio S., Dunseath G., Peter R., Pauvaday V., and Owens D.R. Comparison of the pharmacokinetics and pharmacodynamics of biphasic insulin aspart and insulin glargine in people with type 2 diabetes. Diabetologia 49 (2006) 1163-1168
    • (2006) Diabetologia , vol.49 , pp. 1163-1168
    • Luzio, S.1    Dunseath, G.2    Peter, R.3    Pauvaday, V.4    Owens, D.R.5
  • 52
    • 34248175438 scopus 로고    scopus 로고
    • Using a simple algorithm (ALG) to adjust mealtime glulisine (GLU) based on preprandial glucose patterns is a safe and effective alternative to carbohydrate counting (Carb Count)
    • Abstract 441-P
    • Bergenstal R.M., Johnson M.L., Powers M.A., Wynne A.G., Vlajnic A., and Hollander P.A. Using a simple algorithm (ALG) to adjust mealtime glulisine (GLU) based on preprandial glucose patterns is a safe and effective alternative to carbohydrate counting (Carb Count). Diabetes 55 suppl 1 (2006) Abstract 441-P
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Bergenstal, R.M.1    Johnson, M.L.2    Powers, M.A.3    Wynne, A.G.4    Vlajnic, A.5    Hollander, P.A.6
  • 53
    • 38649103625 scopus 로고    scopus 로고
    • The PREFER Study: both biphasic insulin Aspart 30 (BIAsp 30) twice-daily and basal-bolus using insulin detemir (IDet) and insulin aspart (IAsp) enabled patients with type 2 diabetes to achieve A1c target <7.0%
    • PREFER Study Group [abstract 998]
    • Liebl A., Prager R., Binz K., Kaiser M., Gallwitz B., and PREFER Study Group. The PREFER Study: both biphasic insulin Aspart 30 (BIAsp 30) twice-daily and basal-bolus using insulin detemir (IDet) and insulin aspart (IAsp) enabled patients with type 2 diabetes to achieve A1c target <7.0%. Diabetologia 49 suppl 1 (2006) 610 [abstract 998]
    • (2006) Diabetologia , vol.49 , Issue.SUPPL. 1 , pp. 610
    • Liebl, A.1    Prager, R.2    Binz, K.3    Kaiser, M.4    Gallwitz, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.