Neuroprotective and antiamnesic effect of donepezil, a nicotinic acetylcholine-receptor activator, on rats with concussive mild traumatic brain injury

Journal of Clinical Neuroscience

Volumn 15, Issue 7, 2008, Pages 791-796

  Fujiki, Minoru ^a   Kubo, Takeshi ^a   Kamida, Tohru ^a   Sugita, Kenji ^a   Hikawa, Takamitsu ^a   Abe, Tatsuya ^a   Ishii, Keisuke ^a   Kobayashi, Hidenori ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

Concussion; Donepezil; Memory impairment; Mild traumatic brain injury; Neuronal death; Neuroprotection

Indexed keywords

DONEPEZIL; MECAMYLAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN CONCUSSION; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; HIPPOCAMPUS; MALE; MAZE TEST; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN; BRAIN CONCUSSION; BRAIN INJURIES; CHOLINESTERASE INHIBITORS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; INDANS; MALE; MAZE LEARNING; MEMORY DISORDERS; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; NOOTROPIC AGENTS; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; TREATMENT OUTCOME;

EID: 44249106100     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jocn.2007.07.002     Document Type: Article

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