Vitamin D deficiency, cardiac iron and cardiac function in thalassaemia major

British Journal of Haematology

Volumn 141, Issue 6, 2008, Pages 891-894

  Wood, John C ^a   Claster, Susan ^a   Carson, Susan ^a   Menteer, J D ^a   Hofstra, Thomas ^a   Khanna, Rachna ^a   Coates, Thomas ^a  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

Heart; Iron overload; Magnetic resonance imaging; Thalassaemia major; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; IRON;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; IRON OVERLOAD; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; THALASSEMIA; VITAMIN D DEFICIENCY;

ADOLESCENT; ADULT; BETA-THALASSEMIA; BLOOD TRANSFUSION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; IRON; IRON OVERLOAD; LIVER; MALE; MYOCARDIUM; STROKE VOLUME; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT; VITAMIN D DEFICIENCY;

EID: 44249100902     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2008.07135.x     Document Type: Article

References (15)

1. Bhattacharya, S.K., Ahokas, R.A., Carbone, L.D., Newman, K.P., Gerling, I.C., Sun, Y. Weber, K.T. (2006) Macro- and micronutrients in African-Americans with heart failure. Heart Failure Reviews, 11, 45 55.
2. Billaudel, B.J., Delbancut, A.P., Sutter, B.C. Faure, A.G. (1993) Stimulatory effect of 1,25-dihydroxyvitamin D3 on calcium handling and insulin secretion by islets from vitamin D3-deficient rats. Steroids, 58, 335 341.
3. Chapuy, M.C., Preziosi, P., Maamer, M., Arnaud, S., Galan, P., Hercberg, S. Meunier, P.J. (1997) Prevalence of vitamin D insufficiency in an adult normal population. Osteoporosis International, 7, 439 443.
4. Chiu, K.C., Chu, A., Go, V.L. Saad, M.F. (2004) Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. American Journal of Clinical Nutrition, 79, 820 825.
5. Chow, L.H., Frei, J.V., Hodsman, A.B. Valberg, L.S. (1985) Low serum 25-hydroxyvitamin D in hereditary hemochromatosis: relation to iron status. Gastroenterology, 88, 865 869.
6. Dawson-Hughes, B., Heaney, R.P., Holick, M.F., Lips, P., Meunier, P.J. Vieth, R. (2005) Estimates of optimal vitamin D status. Osteoporosis International, 16, 713 716.
7. Holick, M.F. (2007) Vitamin D deficiency. New England Journal of Medicine, 357, 266 281.
8. Lemmila, S., Saha, H., Virtanen, V., Ala-Houhala, I. Pasternack, A. (1998) Effect of intravenous calcitriol on cardiac systolic and diastolic function in patients on hemodialysis. American Journal of Nephrology, 18, 404 410.
9. Moulas, A., Challa, A., Chaliasos, N. Lapatsanis, P.D. (1997) Vitamin D metabolites (25-hydroxyvitamin D, 24,25-dihydroxyvitamin D and 1,25-dihydroxyvitamin D) and osteocalcin in beta-thalassaemia. Acta Paediatrica, 86, 594 599.
10. Napoli, N., Carmina, E., Bucchieri, S., Sferrazza, C., Rini, G.B. Di Fede, G. (2006) Low serum levels of 25-hydroxy vitamin D in adults affected by thalassemia major or intermedia. Bone, 38, 888 892.
11. Oudit, G.Y., Sun, H., Trivieri, M.G., Koch, S.E., Dawood, F., Ackerley, C., Yazdanpanah, M., Wilson, G.J., Schwartz, A., Liu, P.P. Backx, P.H. (2003) L-type Ca(2+) channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy. Nature Medicine, 9, 1187 1194.
12. Pfeifer, M., Begerow, B. Minne, H.W. (2002) Vitamin D and muscle function. Osteoporosis International, 13, 187 194.
13. Smogorzewski, M. Massry, S.G. (1997) Uremic cardiomyopathy: role of parathyroid hormone. Kidney International. Supplement, 62, S12 14.
14. Thorin, E., Henrion, D., Oster, L., Thorin-Trescases, N., Capdeville, C., Martin, J.A., Chillon, J.M., Hicks, P.E. Atkinson, J. (1990) Vascular calcium overload produced by administration of vitamin D3 and nicotine in rats. Changes in tissue calcium levels, blood pressure, and pressor responses to electrical stimulation or norepinephrine in vivo. Journal of Cardiovascular Pharmacology, 16, 257 266.
15. Wood, J.C., Tyszka, J.M., Ghugre, N., Carson, S., Nelson, M.D. Coates, T.D. (2004) Myocardial iron loading in transfusion-dependent thalassemia and sickle-cell disease. Blood, 103, 1934 1936.