Nimodipine protects PC12 cells against oxygen-glucose deprivation

Iranian Journal of Pharmacology and Therapeutics

Volumn 6, Issue 1, 2007, Pages 51-54

  Rahbar Roshandel, Nahid ^a   Razavi, Lili ^b   Tavakoli Far, Bahareh ^a  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Nimodipine; Oxygen glucose deprivation; PC12 cell line

Indexed keywords

DIZOCILPINE; GLUCOSE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NIMODIPINE; OXYGEN;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL DAMAGE; CELL HYPOXIA; CELL PROTECTION; CELL STRAIN; CELL VIABILITY; CHRONOLOGY; DRUG EFFECT; NONHUMAN; RAT; RECEPTOR UPREGULATION;

EID: 44249095574     PISSN: 17352657     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Olnay JW.Excitotoxic amino acids and neuropsychiatric disorder. Annu. Rev. Pharmacol.Toxical. 1990; 30: 47-71.
2. Choi DW,Rothman SM.The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annual Review of Neuroscience 1990;13:171-182.
3. Beckman JS The double-edged role of nitric oxide in brain function and superoxide mediated injury. J. Dev. Physiol. 1991;15:53-59.
4. Flekenstien A. Specific pharmacology of calcium in myocardium, cardiac pacemakers, and vascular smooth muscle. Ann. Rev. Pharmacol.Toxic.1977;17:149- 166.
5. Blardi P, Urso R, de Lalla A, Volpi L, Di Perri T, Auteri A. Nimodipine;Drug pharmacokinetics and plasma adenosine levels in patients affected by cerebral ischemia. Clin. Pharmacol. Ther. 2002;72:551-566.
6. Dreir JP, Windmuller O, Petzold G, Lindauer U, Einhaupl KM, Dirnaugl U..Ischemic triggerd by red blood cell products in the subarachnoid space in ihibited by nimpodipine administration or moderate volume expansion/hemodilution in rats. Neurosurgery 2002;51:1457-1465.
7. Rinkel GJ, Feigin VL, Algra A, Vermeulen M, van Gijn J. Calcium antagonists for aneurismal subarachnoid haemorrhage cochrane. Database Syst. Rev. 2002;4: CD000277.
8. Trust Study Group. Randimized, double blind, placebo controlled trial if nimodipine I acute stroke. Lance . 1990;336:1205-1209.
9. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods . 1983;65: 55-63.
10. Frantsevan MV, Carlen PL, El-Beheiry, H.A submersion method to induce hypoxic damage in organotypic hippocampal cultures. J. Neurosci. Methods 1999;89: 25-31.
11. Kornekov AL, Pahnake J, Frei K, Warzok R, Schroder HW, Frick R, Muljana L, Piek J, Yonekawa Y. Treatment with nimodipine and mannitol reduces programed cell and infarct size following focal cerebral ischemia. Neurosurg.Rev.2000; 23: 145-150.
12. Gepdiremen A, Duzenli S, Hacimuftuoglu A, Suleyman H, Oztas S.The effects of dantroline alone or in combination with nimodipine in glutamate-induced neurotoxicity in cerebellar granular cell cultures of rat pups. Pharmacological Research 2000;43: 241-244.
13. Bleich S, Romer K, Wiltfang J, Kornhuber J. Glutamate and the glutamate receptor system: a target for drug action.International Journal of Geriatric Psychiatry . 2003;18: S33-S40.
14. Conn PJ.Physiological roles and therapeutic potential of metabotropic glutamate receptors. Annals of the New York Academy of Science 2003;1003: 12-21.
15. Choi DW, .Ionic dependence of glutamate neurotoxicity. Journal of Neuroscience 1987;7: 369-379.
16. Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 1995;15: 961-973.
17. Rothman SM, Olney JW.Glutamate and pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 1986;19: 105-111.
18. 2+] in hypoxia and ischemia in rat brain in vivo. J. Gen. Physiol. 1990;5: 837-866.
19. Kritian T, Siesjo BK Calcium-related damage in ischemia. Life Sciences 1996;59: 357-367.
20. Jabaudon D, Scanziani M, Gahwiler BH, Gerber U.Acute decrease in net glutamate uptake during energy deprivation. Proc.Natl.Acad. Sci.U.S.A 2000;97:5610-5615.
21. NishizawaY.Glutamate release and neuronal damage in ischemia. Life Sci.2001; 69: 369-381.
22. Benvenga MJ, Spaulding TC.Amnesic effect of the novel anticonvulsant MK-801. Pharmacology Biochemistry and Behavior 1988;30: 205-207.