Indirect oxidation of the antitumor agent procarbazine by tyrosinase-Possible application in designing anti-melanoma prodrugs

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 11, 2008, Pages 3296-3300

  Gasowska Bajger, Beata ^a   Wojtasek, Hubert ^a  

^a UNIVERSITY OF OPOLE   (Poland)

Author keywords

Hydrazine; Melanoma; Prodrug; Redox exchange; Tyrosinase

Indexed keywords

4 TERT BUTYLCATECHOL; AZOPROCARBAZINE; DRUG METABOLITE; MONOPHENOL MONOOXYGENASE; N ACETYLTYROSINE; PROCARBAZINE; PRODRUG;

ARTICLE; DRUG DEGRADATION; DRUG DESIGN; DRUG STRUCTURE; ENZYME SUBSTRATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MELANOMA; OXIDATION; OXYGEN CONSUMPTION;

AGARICALES; ANTINEOPLASTIC AGENTS; HYDRAZINES; MELANOMA; MOLECULAR STRUCTURE; MONOPHENOL MONOOXYGENASE; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PROCARBAZINE; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 44149116743     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.04.041     Document Type: Article

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