Melanocyte-directed enzyme prodrug therapy (MDEPT): Development of a targeted treatment for malignant melanoma

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 9, 1999, Pages 1775-1780

  Jordan, Allan M ^a   Khan, Tariq H ^b   Osborn, Helen M I ^a   Photiou, Andrew ^c   Riley, Patrick A ^d  

^a UNIVERSITY OF READING   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c ST THOMAS HOSPITAL   (United Kingdom)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Antitumour compound; Melanoma; Prodrug; Tyrosinase

Indexed keywords

CARBAMIC ACID DERIVATIVE; PRODRUG; UNCLASSIFIED DRUG; [2 (3,4 DIHYDROXYPHENYL)ETHYL]CARBAMIC ACID 4 BIS(2 CHLOROETHYLAMINO)PHENYL ESTER;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; DRUG ACTIVITY; DRUG RELEASE; DRUG SCREENING; DRUG SYNTHESIS; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA; NONHUMAN;

EID: 0032860282     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00126-1     Document Type: Article

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