Enhanced bio-molecular interactions through recirculating microflows

IET Nanobiotechnology

Volumn 2, Issue 2, 2008, Pages 39-46

  Chandrasekaran, A ^a   Packirisamy, M ^a  

^a Dept of Electrical and Computer Engineering   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BIOMOLECULES; FINITE ELEMENT METHOD; FLOW CONTROL; MOLECULAR INTERACTIONS;

ANTISHEEP ANTIBODY (AB); BIOMOLECULAR INTERACTIONS; MICROFLOWS; MICROFLUIDIC CHANNELS;

MICROFLUIDICS;

ANTIBODY; FLUORESCENT DYE;

ANIMAL; ARTICLE; CELL SEPARATION; CHEMISTRY; EQUIPMENT DESIGN; FINITE ELEMENT ANALYSIS; FLOW CYTOMETRY; GENETIC PROCEDURES; INSTRUMENTATION; METHODOLOGY; MICROFLUIDIC ANALYSIS; MICROFLUIDICS; THEORETICAL MODEL;

ANIMALS; ANTIBODIES; BIOSENSING TECHNIQUES; CELL SEPARATION; EQUIPMENT DESIGN; FINITE ELEMENT ANALYSIS; FLOW CYTOMETRY; FLUORESCENT DYES; MICROCHEMISTRY; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROFLUIDICS; MODELS, THEORETICAL;

EID: 44149111869     PISSN: 17518741     EISSN: None     Source Type: Journal    
DOI: 10.1049/iet-nbt:20070029     Document Type: Article

References (21)

1. Krenková, J., and Foret, F.: ' Immobilized microfluidic enzymatic reactors ', Electrophoresis, 2004, 25, p. 3550-3563 0173-0835
2. Chandrasekaran, A., and Packirisamy, M.: ' Absorption detection of enzymatic reaction using optical microfluidics based intermittent flow microreactor system ', J. Nanobiotechnol., 2006, 153, (6), p. 137-143
3. Chandrasekaran, A., and Packirisamy, M.: ' Absorption detection of enzymatic reaction using hybrid integrated biophotonic microfluidic system ', Photons, 2006, 4, p. 27-31
4. Chen, J.M., Horng, T.L., and Tan, W.Y.: ' Analysis and measurements of mixing in pressure-driven microchannel flow ', J. Microfluidics Nanofluidics, 2006, 2, (6), p. 455-469
5. Islam, N., and Wu, J.: ' Microfluidic transport by AC electroosmosis ', J. Phys., 2006, 34, p. 356-361 0302-0738
6. Johann, R.M.: ' Cell trapping in microfluidic chips ', Anal. Bioanalytical Chem., 2006, 385, p. 408-412
7. Youlan, Li, Colin, Dalton, John Crabtree, H., Gregory, Nilsson, and Karan, Kaler: ' Continuous dielectrophoretic cell separation microfluidic device ', 2007, 7, p. 239-248, Lab-on-a-chip
8. Mirowski, E., Moreland, J., Russek, S.E., and Donahue, M.J.: ' Integrated microfluidic isolation platform for magnetic particle manipulation in biological systems ', Appl. Phys. Lett., 84, (10), p. 1786-1788 0003-6951
9. Gan, H.Y., Lam, Y.C., and Nguyen, N.T.: ' Polymer-based device for efficient mixing of viscoelastic fluids ', Appl. Phys. Lett., 2006, 88, (22) 0003-6951
10. Gan, H.Y., Lam, Y.C., Nguyen, N.T., Tam, K.C., and Yang, C.: ' Efficient mixing of viscoelastic fluids in a microchannel at low Reynolds number ', J. Microfluidics Nanofluidics, 2007, 3, (1), p. 101-108
11. Yadavalli, V.K., and Pishko, M.V.: ' Biosensing in microfluidic channels using fluorescence polarization ', Anal. Chim. Acta, 2004, 507, (1), p. 123-128
12. Studer, V., Jameson, R., Pellereau, E., Pépin, A., and Chen, Y.: ' A microfluidic mammalian cell sorter based on fluorescence detection ', Microelectron. Eng., 2004, 73-74, p. 852-857 0167-9317
13. Gao, X., Cui, Y., Levenson, R.M., Chung, L.W.K., and Nie, S.: ' In vivo cancer targeting and imaging with semiconductor quantum dots ', Nature Biotechnol., 2004, 22, p. 969-976
14. 3 beads-CdSe/ZnS quantum dots core-shell nanocomposite particles for cell separation ', Nano Lett., 2004, 4, p. 409 1530-6984
15. Kingsley, J.D., Dou, H., Morehead, J., Rabinow, B., Gendelman, H.E., and Destache, C.J.: ' Nanotechnology: a focus on nanoparticles as a drug delivery system ', J. NeuroImmune Pharmacol., 2006, 1, (3), p. 340-350
16. Bailey, R.E., Smith, A.M., and Nie, S.: ' Quantum dots in biology and medicine ', Phys. E, 2004, 25, p. 1-12
17. Protolyne Microfluidic Process Technology, Micralyne Inc., 1911-94 Street, Edmonton, Alberta, Canada T6N 1E6
18. Nguyen, N.T., and Wereley, S.T.: ' Fundamentals and application of microfluidics ', (Artech House Pub., 2002)
19. FEMLAB, available at: http://www.femlab.com
20. Shelby, J.P., Lim, D.S.W., Kuo, J.S., and Chiu, D.T.: ' High radial acceleration in microvortices ', Nature, 2003, 425, p. 38 0028-0836
21. Lim, D.S.W., Shelby, J.P., Kuo, J.S., and Chiu, D.T.: ' Dynamic formation of ring-shaped patterns of colloidal particles in microfluidic systems', Appl. Phys. Lett. ', 83, (6), p. 1145-1147