Radionuclide evaluation of the lower gastrointestinal tract

Journal of Nuclear Medicine

Volumn 49, Issue 5, 2008, Pages 776-787

  Mariani, Giuliano ^a   Pauwels, Ernest K J ^a,b   AlSharif, Abedallatif ^a   Marchi, Santino ^a   Boni, Giuseppe ^a   Barreca, Marco ^c   Bellini, Massimo ^a   Grosso, Mariano ^a   De Bortoli, Nicola ^a   Mumolo, Gloria ^a   Costa, Francesco ^a   Rubello, Domenico ^d   Strauss, H William ^e  

^a UNIVERSITY OF PISA   (Italy)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF PISA   (Italy)

^d S MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Gastrointestinal; GI; Radionuclide; Transit scintigraphy

Indexed keywords

8 QUINOLINOL INDIUM IN 111; CALCIUM CHANNEL BLOCKING AGENT; CHLORIDE IN 111; DIGOXIN; DIPYRIDAMOLE; ETIDRONIC ACID TC 99M; FLUORODEOXYGLUCOSE F 18; HEPARIN; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; INDIUM 111; IODINE 131; LAXATIVE; METRONIDAZOLE; PENTETATE INDIUM IN 111; PENTETATE TECHNETIUM TC 99M; PERTECHNETIC ACID TC 99M; PROKINETIC AGENT; PROPRANOLOL; QUINIDINE; RADIOISOTOPE; RANITIDINE; TECHNETIUM 99M; TECHNETIUM SULFUR COLLOID TC 99M;

COLON; COLON CANCER; COLON RESECTION; COMPUTER ASSISTED TOMOGRAPHY; CONSTIPATION; CROHN DISEASE; DEFECOGRAPHY; DIAGNOSTIC PROCEDURE; DIARRHEA; ENTERITIS; FEEDBACK SYSTEM; GASTROINTESTINAL DISEASE; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL OBSTRUCTION; GASTROINTESTINAL TRACT SCINTISCANNING; HEALTH CARE COST; HUMAN; IRRITABLE COLON; LACTOSE INTOLERANCE; MECKEL DIVERTICULUM; NONHUMAN; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SMALL INTESTINE; STOMACH EMPTYING; TRANSIT SCINTIGRAPHY; ULCERATIVE COLITIS;

CONSTIPATION; DEFECOGRAPHY; DIARRHEA; HEMORRHAGE; HUMANS; LOWER GASTROINTESTINAL TRACT; RADIONUCLIDE IMAGING;

EID: 44149111117     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.040113     Document Type: Review

References (80)

1. Mariani G, Boni G, Barreca M, et al. Radionuclide gastroesophageal motor studies. J Nucl Med. 2004;45:1004-1028.
2. Locke GR III, Pemberton JH, Phillips SF. AGA technical review on constipation. American Gastroenterological Association. Gastroenterology. 2000;119:1766-1778.
3. Hellard ME, Sinclair MI, Harris AH, Kirk M, Fairley CK. Cost of community gastroenteritis. J Gastroenterol Hepatol. 2003;18:322-328.
4. Sandler RS, Everhart JE, Donowitz M, et al. The burden of selected digestive diseases in the United States. Gastroenterology. 2002;122:1500-1511.
5. Lipsky MS, Adelman M. Chronic diarrhea: evaluation and treatment. Am Fam Physician. 1993;48:1461-1466.
6. Wilson S, Roberts L, Roalfe A, Bridge P, Singh S. Prevalence of irritable bowel syndrome: a community survey. Br J Gen Pract. 2004;54:495-502.
7. Bodger K. Cost of illness of Crohn's disease. Pharmacoeconomics. 2002;20:639-652.
8. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006;130:1480-1491.
9. Talley NJ. Management of chronic constipation. Rev Gastroenterol Disord. 2004;4:18-24.
10. Lembo A, Camilleri M. Chronic constipation. N Engl J Med. 2003;349:1360-1368.
11. Prather CM. Subtypes of constipation: sorting out the confusion. Rev Gastroenterol Disord. 2004;4(suppl 2):S11-S16.
12. Longstreth GF. Epidemiology and outcome of patients hospitalized with acute lower gastrointestinal hemorrhage: a population-based study. Am J Gastroenterol. 1997;92:419-424.
13. Lanas A, Sekar MC, Hirschowitz BI. Objective evidence of aspirin use in both ulcer and nonulcer upper and lower gastrointestinal bleeding. Gastroenterology. 1992;103:862-869.
14. Elton E, Howell DA, Amberson SM, Dykes TA. Combined angiographic and endoscopic management of bleeding pancreatic pseudoaneurysms. Gastrointest Endosc. 1997;46:544-549.
15. Chak A, Cooper GS, Lloyd LE, Kolz CS, Barnhart BA, Wong RC. Effectiveness of endoscopy in patients admitted to the intensive care unit with upper GI hemorrhage. Gastrointest Endosc. 2001;53:6-13.
16. Boley SJ, DiBiase A, Brandt LJ, Sammartano RJ. Lower intestinal bleeding in the elderly. Am J Surg. 1979;137:57-64.
17. Peura DA, Lanza FL, Gostout CJ, Foutch PG. The American College of Gastroenterology Bleeding Registry: preliminary findings. Am J Gastroenterol. 1997;92:924-928.
18. Zuckerman GR, Prakash C. Acute lower intestinal bleeding. Part II: etiology, therapy, and outcomes. Gastrointest Endosc. 1999;49:228-238.
19. Huguier M, Barrier A, Boelle PY, Houry S, Lacaine F. Ischemic colitis. Am J Surg. 2006;192:679-684.
20. Meckel JF. Ueber die Divertikel am Darmkanal. Archiv Physiol (Halle). 1809; 9:421-453.
21. Blackshear JL, Baker VS, Holland A, et al. Fecal hemoglobin excretion in elderly patients with atrial fibrillation: combined aspirin and low-dose warfarin vs conventional warfarin therapy. Arch Intern Med. 1996;156:658-660.
22. Lin HC, Prather C, Fischer RS, et al. Measurement of gastrointestinal transit. Dig Dis Sci. 2005;50:989-1004.
23. Lin HC, Zhao XT, Wang L. Jejunal brake: inhibition of intestinal transit by fat in the proximal small intestine. Dig Dis Sci. 1996;41:326-329.
24. Van Citters GW, Lin HC. The ileal brake: a fifteen-year progress report. Curr Gastroenterol Rep. 1999;1:404-409.
25. Bonapace ES, Maurer AH, Davidoff S, Krevsky B, Fisher RS, Parkman HP. Whole gut transit scintigraphy in the clinical evaluation of patients with upper and lower gastrointestinal symptoms. Am J Gastroenterol. 2000;95:2838-2847.
26. Proano M, Camilleri M, Phillips SF, Brown ML, Thomforde GM. Transit of solids through the human colon: regional quantification in the unprepared bowel. Am J Physiol. 1990;258:G856-G862.
27. Burton DD, Camilleri M, Mullan BP, Forstrom LA, Hung JC. Colonic transit scintigraphy labeled activated charcoal compared with ion exchange pellets. J Nucl Med. 1997;38:1807-1810.
28. Maurer AH, Parkman HP. Update on gastrointestinal scintigraphy. Semin Nucl Med. 2006;36:110-118.
29. Malagelada JR, Robertson JS, Brown ML, et al. Intestinal transit of solid and liquid components of a meal in health. Gastroenterology. 1984;87:1255-1263.
30. Bennink R, Peeters M, Van den Maegdenbergh V, et al. Evaluation of small-bowel transit for solid and liquid test meal in healthy men and women. Eur J Nucl Med. 1999;26:1560-1566.
31. Camilleri M, Zinsmeister AR, Greydanus MP, Brown ML, Proano M. Towards a less costly but accurate test of gastric emptying and small bowel transit. Dig Dis Sci. 1991;36:609-615.
32. 111indium-labelled diethylenetriamine penta-acetic acid. Clin Physiol Funct Imaging. 2003;23:204-207.
33. Mason HJ, Serrano-Ikkos E, Kamm MA. Psychological morbidity in women with idiopathic constipation. Am J Gastroenterol. 2000;95:2852-2857.
34. Chitkara DK, Delgado-Aros S, Bredenoord AJ, et al. Functional dyspepsia, upper gastrointestinal symptoms, and transit in children. J Pediatr. 2003;143:609-613.
35. Vassallo M, Camilleri M, Phillips SF, Brown ML, Chapman NJ, Thomforde GM. Transit through the proximal colon influences stool weight in the irritable bowel syndrome. Gastroenterology. 1992;102:102-108.
36. Ford PV, Bartold SP, Fink-Bennett DM, et al. Procedure guideline for gastrointestinal bleeding and Meckel's diverticulum scintigraphy. Society of Nuclear Medicine. J Nucl Med. 1999;40:1226-1232.
37. O'Neill BB, Gosnell JE, Lull RJ, et al. Cinematic nuclear scintigraphy reliably directs surgical intervention for patients with gastrointestinal bleeding. Arch Surg. 2000;135:1076-1081.
38. 99mTc-labeled erythrocyte scintigraphy in patients with lower gastrointestinal tract hemorrhage: effect of positive findings on clinical management. Acad Radiol. 2003;10:497-501.
39. 99mTc RBC scintigraphy: correlation of gastrointestinal bleeding rates with scintigraphic findings. AJR. 1987;148:869-874.
40. Jacobson AF, Cerqueira MD. Prognostic significance of late imaging results in technetium-99m-labeled red blood cell gastrointestinal bleeding studies with early negative images. J Nucl Med. 1992;33:202-207.
41. Thorne DA, Datz FL, Remley K, Christian PE. Bleeding rates necessary for detecting acute gastrointestinal bleeding with technetium-99m-labeled red blood cells in an experimental model. J Nucl Med. 1987;28:514-520.
42. 99mTechnetium-labelled red blood cell scintigraphy as an alternative to angiography in the investigation of gastrointestinal bleeding: clinical experience in a district general hospital. Ann R Coll Surg Engl. 1992;74:192-199.
43. 99mTc sulfur colloid. AJR. 1984;143:543-548.
44. Siddiqui AR, Schauwecker DS, Wellman HN, Mock BH. Comparison of technetium-99m sulfur colloid and in vitro labeled technetium-99m RBCs in the detection of gastrointestinal bleeding. Clin Nucl Med. 1985;10:546-549.
45. Callahan RJ, Froelich JW, McKusick KA, Leppo J, Strauss HW. A modified method for the in vivo labeling of red blood cells with Tc-99m: concise communication. J Nucl Med. 1982;23:315-318.
46. Seldin DW, Simchon S, Jan KM, Chien S, Alderson PO. Dependence of technetium-99m red blood cell labeling efficiency on red cell surface charge. J Nucl Med. 1988;29:1710-1713.
47. Maurer AH, Rodman MS, Vitti RA, Revez G, Krevsky B. Gastrointestinal bleeding: improved localization with cine scintigraphy. Radiology. 1992;185:187-192.
48. Zettinig G, Staudenherz A, Leitha T. The importance of delayed images in gastrointestinal bleeding scintigraphy. Nucl Med Commun. 2002;23:803-808.
49. Nwakanma L, Meyerrose G, Kennedy S, Rakvit A, Bohannon T, Silva M. Recurrent gastrointestinal bleeding diagnosed by delayed scintigraphy with Tc-99m-labeled red blood cells. Clin Nucl Med. 2003;28:691-693.
50. Yama N, Ezoe E, Kimura Y, et al. Localization of intestinal bleeding using a fusion of Tc-99m-labeled RBC SPECT and x-ray CT. Clin Nucl Med. 2005;30:488-489.
51. Schillaci O, Filippi L, Danieli R, Simonetti G. Single-photon emission computed tomography/computed tomography in abdominal diseases. Semin Nucl Med. 2007;37:48-61.
52. Maurer AH. Gastrointestinal bleeding. In: Ell PJ, Gambhir GG, eds. Nuclear Medicine in Clinical Diagnosis and Treatment. 3rd ed. Sydney, Australia: Churchill Livingstone; 2004:911-917.
53. Sfakianakis GN, Conway JJ. Detection of ectopic gastric mucosa in Meckel's diverticulum and in other aberrations of scintigraphy: I: pathophysiology and 10 year clinical experience. J Nucl Med. 1981;22:647-654.
54. Sfakianakis GN, Haase GM. Abdominal scintigraphy for ectopic gastric mucosa: a retrospective analysis of 143 studies. AJR. 1982;138:7-12.
55. Kong MS, Chen CY, Tzen KY, et al. Technetium-99m pertechnetate scan for ectopic gastric mucosa in children with gastrointestinal bleeding. J Formos Med Assoc. 1993;92:717-720.
56. Connolly LP, Treves ST, Bozorgi F, O'Connor SC. Meckel's diverticulum: demonstration of heterotopic gastric mucosa with technetium-99m-pertechnetate SPECT. J Nucl Med. 1998;39:1458-1460.
57. Brown ML. Gastrointestinal bleeding. In: Wagner HN, Szabo Z, Buchanan JW, eds. Principles of Nuclear Medicine. 2nd ed. Philadelphia, PA: W.B. Saunders Co.; 1995:929-934.
58. Muller WA. Leukocyte-endothelial cell interactions in the inflammatory response. Lab Invest. 2002;82:521-533.
59. Charron M, Orenstein SR, Bhargava S. Detection of inflammatory bowel disease in pediatric patients with technetium-99m-HMPAO-labeled leukocytes. J Nucl Med. 1994;35:451-455.
60. m HMPAO leucocyte scintigraphy distinguish between Crohn's disease and ulcerative colitis? Br J Radiol. 1994;67:472-477.
61. Datz FL, Seabold JE, Brown ML, et al. Procedure guideline for technetium-99m-HMPAO-labeled leukocyte scintigraphy for suspected infection/inflammation. Society of Nuclear Medicine. J Nucl Med. 1997;38:987-990.
62. Seabold JE, Forstrom LA, Schauwecker DS, et al. Procedure guideline for indium-111-leukocyte scintigraphy for suspected infection/inflammation. Society of Nuclear Medicine. J Nucl Med. 1997;38:997-1001.
63. Martin-Comin J, Prats E. Clinical applications of radiolabeled blood elements in inflammatory bowel disease. Q J Nucl Med. 1999;43:74-82.
64. Annovazzi A, Bagni B, Burroni L, D'Alessandria C, Signore A. Nuclear medicine imaging of inflammatory/infective disorders of the abdomen. Nucl Med Commun. 2005;26:657-664.
65. Yamada S, Kubota K, Kubota R, Ido T, Tamahashi N. High accumulation of fluorine-18-fluorodeoxyglucose in turpentine-induced inflammatory tissue. J Nucl Med. 1995;36:1301-1306.
66. Love C, Tomas MB, Tronco GG, Palestro CJ. FDG PET of infection and inflammation. Radiographics. 2005;25:1357-1368.
67. Bicik I, Bauerfeind P, Breitbach T, von Schultess GK, Fried M. Inflammatory bowel disease activity measured by positron-emission tomography [letter]. Lancet. 1997;350:262.
68. 18F-Fluorodeoxyglucose positron tomography in diagnosis of paediatric inflammatory bowel disease. Lancet. 1999;354:836-837.
69. Lemberg DA, Issenman RM, Cawdron R, et al. Positron emission tomography in the investigation of pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2005;11:733-738.
70. 18F-FDGPET in pediatric patients with chronic inflammatory bowel disease. Ann N Y Acad Sci. 2006;1072:379-385.
71. 18F-fluorodeoxyglucose positron emission tomography, hydromagnetic resonance imaging, and granulocyte scintigraphy with labeled antibodies. Am J Gastroenterol. 2002;97:1978-1985.
72. 18F-FDG PET/CT. J Nucl Med. 2007;48:1053-1059.
73. Whitehead WE, Wald A, Diamant NE, Enck P, Pemberton JH, Rao SSC. Functional disorders of the anus and rectum. Gut. 1999;45(suppl 2):1155-1159.
74. O'Connell PR, Kelly KA, Brown ML. Scintigraphic assessment of neorectal function. J Nucl Med. 1986;27:460-464.
75. Barkel DC, Pemberton JH, Pezim ME, et al. Scintigraphic assessment of the anorectal angle in health and after ileal pouch-anal anastomosis. Ann Surg. 1988;208:42-49.
76. Papachrysostomou M, GriffinTM, Ferrington C, Merrick MV, Smith AN. A method of computerised isotope dynamic proctography. Eur J Nucl Med. 1992;19:431-435.
77. Papachrysostomou M, Smith AN, Merrick MV. Obstructive defaecation and slow transit constipation: the proctographic parameters. Int J Colorectal Dis. 1994;9:115-120.
78. Wald A, Jafri F, Rehder J, Holeva K. Scintigraphic studies of rectal emptying in patients with constipation and defecatory difficulty. Dig Dis Sci. 1993;38:353-358.
79. Lubowski DZ, Meagher AP, Smart RC, Butler SP. Scintigraphic assessment of colonic function during defaecation. Int J Colorectal Dis. 1995;10:91-93.
80. Selvaggi F, Cuocolo A, Giuliani A, et al. The role of scintigraphic defecography in the assessment of bowel function after restorative proctocolectomy for ulcerative colitis. Int J Colorectal Dis. 2006;21:448-452.