The reduced local lymph node assay: The impact of group size

Journal of Applied Toxicology

Volumn 28, Issue 4, 2008, Pages 518-523

  Ryan, Cindy A ^a   Chaney, Joel G ^a   Kern, Petra S ^a   Patlewicz, Grace Y ^b   Basketter, David A ^c   Betts, Catherine J ^d   Dearman, Rebecca J ^d   Kimber, Ian ^d   Gerberick, G Frank ^a  

^a PROCTER AND GAMBLE COMPANY   (United States)

^b JOINT RESEARCH CENTRE   (Italy)

^c UNILEVER RESEARCH   (United Kingdom)

^d JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

Hazard identification; Local lymph node assay; Skin sensitization potential screening

Indexed keywords

ALLERGEN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; HAZARD ASSESSMENT; LOCAL LYMPH NODE ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCREENING; SKIN SENSITIZATION;

ALLERGENS; ANIMALS; DERMATITIS, ALLERGIC CONTACT; DERMATITIS, CONTACT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEASIBILITY STUDIES; FEMALE; IRRITANTS; LOCAL LYMPH NODE ASSAY; LYMPH NODES; MICE; MICE, INBRED CBA; REPRODUCIBILITY OF RESULTS; RESEARCH DESIGN; RISK ASSESSMENT; SAMPLE SIZE;

ANIMALIA; MUS;

EID: 44149104083     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1303     Document Type: Article

References (9)

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8. Organisation for Economic Coooperation and Development. 2002. Test Guideline 429: The local Lymph Node Assay. OECD: Paris.
9. United States Environmental Protection Agency. 2003. Health Effects Test Guidelines: OPPTS 870.2600 Skin Sensitization. US EPA: Washington, DC.