Macrophage depletion diminishes implant-wear-induced inflammatory osteolysis in a mouse model

Journal of Biomedical Materials Research - Part A

Volumn 85, Issue 4, 2008, Pages 1043-1051

  Ren, Weiping ^a   Markel, David C ^b   Schwendener, Reto ^c   Ding, Yunhong ^b   Wu, Bin ^b   Wooley, Paul H ^b  

^a Wayne State University   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Animal model; Aseptic loosening, osteolysis; Clodronate; Liposome; Macrophage; Macrophage depletion, wear debris; Osteoclastogenesis

Indexed keywords

COLLAGEN; LIPOSOMES; RATS; TUMORS; ULTRAHIGH MOLECULAR WEIGHT POLYETHYLENES;

ASEPTIC LOOSENING; CLODRONATE; MACROPHAGE DEPLETION; OSTEOCLASTOGENESIS;

MACROPHAGES;

CLODRONIC ACID; INTERLEUKIN 1BETA; LIPOSOME; TUMOR NECROSIS FACTOR ALPHA; ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALVARIA; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMPLANT; IMPLANTATION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; OSTEOLYSIS; PROSTHESIS LOOSENING;

ACID PHOSPHATASE; ANIMALS; BONE AND BONES; BONE RESORPTION; CLODRONIC ACID; COLLAGEN; FEMALE; IMPLANTS, EXPERIMENTAL; INFLAMMATION; INTERLEUKIN-1BETA; ISOENZYMES; LIPOSOMES; MACROPHAGES; MEMBRANES; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; MOLECULAR WEIGHT; OSTEOCLASTS; OSTEOLYSIS; POLYETHYLENE; PROTECTIVE AGENTS; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 44149089811     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31665     Document Type: Article

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