메뉴 건너뛰기




Volumn 4, Issue 2, 2008, Pages 459-464

Alemtuzumab in the up-front setting

Author keywords

11q deletion; 17p deletion; Alemtuzumab; Chronic lymphocytic leukemia; Consolidation; Miniimal residual disease

Indexed keywords

ALEMTUZUMAB; ANTIBIOTIC AGENT; ANTIVIRUS AGENT; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; FLUDARABINE; GANCICLOVIR; PROTEIN P53; PURINE DERIVATIVE; RITUXIMAB;

EID: 44049101391     PISSN: 11766336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (5)

References (23)
  • 1
    • 0030964964 scopus 로고    scopus 로고
    • In vivo purging of residual disease in CLL with Campath-1H
    • Dyer MJ, Kelsey SM, Mackay HJ, et al. 1997. In vivo purging of residual disease in CLL with Campath-1H. Br J Haematol, 97:669-72.
    • (1997) Br J Haematol , vol.97 , pp. 669-672
    • Dyer, M.J.1    Kelsey, S.M.2    Mackay, H.J.3
  • 2
    • 27244451794 scopus 로고    scopus 로고
    • Fludarabine in combination with alemtuzumab is effective and feasible in patients with relapsed or refractory B-cell chronic lymphocytic leukemia results of phase II trial
    • Elter T, Borchmann P, Schultz H, et al. 2005. Fludarabine in combination with alemtuzumab is effective and feasible in patients with relapsed or refractory B-cell chronic lymphocytic leukemia results of phase II trial. J Clin Oncol, 23:7024-31.
    • (2005) J Clin Oncol , vol.23 , pp. 7024-7031
    • Elter, T.1    Borchmann, P.2    Schultz, H.3
  • 3
    • 0038724252 scopus 로고    scopus 로고
    • Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies
    • Faderl S, Thomas DA, O'Brien S, et al. 2003. Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies. Blood, 101:3413-5.
    • (2003) Blood , vol.101 , pp. 3413-3415
    • Faderl, S.1    Thomas, D.A.2    O'Brien, S.3
  • 4
    • 33746787078 scopus 로고    scopus 로고
    • Preliminary phase III efficacy and safety of alemtuzumab vs chlorambucil as front-line therapy for patients with progressive B-cell chronic lymphocytic leukemia (BCLL) [abstract]
    • 339s. Abstract 6511
    • Hillmen P, Skotnicki A, Robak T, et al. 2006. Preliminary phase III efficacy and safety of alemtuzumab vs chlorambucil as front-line therapy for patients with progressive B-cell chronic lymphocytic leukemia (BCLL) [abstract]. J Clinc Oncol, 24(Suppl):339s. Abstract 6511.
    • (2006) J Clinc Oncol , vol.24 , Issue.SUPPL.
    • Hillmen, P.1    Skotnicki, A.2    Robak, T.3
  • 5
    • 37649004407 scopus 로고    scopus 로고
    • Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia
    • Hillmen P, Skotnicki A, Robak T, et al. 2007. Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia. J Clin Oncol, 25:5616-23.
    • (2007) J Clin Oncol , vol.25 , pp. 5616-5623
    • Hillmen, P.1    Skotnicki, A.2    Robak, T.3
  • 6
    • 0037092951 scopus 로고    scopus 로고
    • Therapeutic role of alemtuzumab (Campath 1-H) in patients who have failed fludarabine: Results of a large international study
    • Keating MJ, Flinn I, Jain V, et al. 2002. Therapeutic role of alemtuzumab (Campath 1-H) in patients who have failed fludarabine: results of a large international study. Blood, 99:3554-61.
    • (2002) Blood , vol.99 , pp. 3554-3561
    • Keating, M.J.1    Flinn, I.2    Jain, V.3
  • 7
    • 0037085770 scopus 로고    scopus 로고
    • Campath-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia
    • Kennedy B, Rawstron A, Carter C, et al. 2002. Campath-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia. Blood, 99:2245-47.
    • (2002) Blood , vol.99 , pp. 2245-2247
    • Kennedy, B.1    Rawstron, A.2    Carter, C.3
  • 8
    • 11144357657 scopus 로고    scopus 로고
    • Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
    • Lozanski G, Heerema NA, Flinn IW, et al. 2004. Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood, 103:3278-81.
    • (2004) Blood , vol.103 , pp. 3278-3281
    • Lozanski, G.1    Heerema, N.A.2    Flinn, I.W.3
  • 9
    • 0036683449 scopus 로고    scopus 로고
    • Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath 1-H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)
    • Lundin J, Kimby E, Bjorkholm M, et al. 2002. Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath 1-H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL). Blood, 100:768-73.
    • (2002) Blood , vol.100 , pp. 768-773
    • Lundin, J.1    Kimby, E.2    Bjorkholm, M.3
  • 10
    • 33745299246 scopus 로고    scopus 로고
    • Infectious complications associated with alemtuzumab use for lymphoproliferative disorders
    • Martin SI, Marty FM, Fiumara K, et al. 2006. Infectious complications associated with alemtuzumab use for lymphoproliferative disorders. Clin Infect Dis, 43:16-24.
    • (2006) Clin Infect Dis , vol.43 , pp. 16-24
    • Martin, S.I.1    Marty, F.M.2    Fiumara, K.3
  • 11
    • 33744793781 scopus 로고    scopus 로고
    • Alemtuzumab as consolidation after a response to fludarabine is effective in purging residual disease in patients with chronic lymphocytic leukemia
    • Montillo M, Tedeschi A, et al. 2006. Alemtuzumab as consolidation after a response to fludarabine is effective in purging residual disease in patients with chronic lymphocytic leukemia. J Clin Oncol, 24:2337-42.
    • (2006) J Clin Oncol , vol.24 , pp. 2337-2342
    • Montillo, M.1    Tedeschi, A.2
  • 12
    • 19444382822 scopus 로고    scopus 로고
    • Treatment of chronic lymphocytic leukemia: Achieving minimal residual disease negative status as a goal
    • Montserrat E. 2005. Treatment of chronic lymphocytic leukemia: achieving minimal residual disease negative status as a goal. J Clin Oncol, 23:2884-5.
    • (2005) J Clin Oncol , vol.23 , pp. 2884-2885
    • Montserrat, E.1
  • 13
    • 21144456107 scopus 로고    scopus 로고
    • Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival
    • Moreton P, Kennedy B, Lucas G, et al. 2005. Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival. J Clin Oncol, 23:2971-79.
    • (2005) J Clin Oncol , vol.23 , pp. 2971-2979
    • Moreton, P.1    Kennedy, B.2    Lucas, G.3
  • 14
    • 0344236261 scopus 로고    scopus 로고
    • Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia
    • O'Brien SM, Kantarjian HM, Thomas DA, et al. 2003. Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia. Cancer, 98:2657-63,
    • (2003) Cancer , vol.98 , pp. 2657-2663
    • O'Brien, S.M.1    Kantarjian, H.M.2    Thomas, D.A.3
  • 15
    • 33750199616 scopus 로고    scopus 로고
    • O'Brien, Keating MJ, Mocarski ES. 2006. Updated guidelines on the management of cytomegalovirus reactivation in patients with chronic lymphocytic leukemia treated with alemtuzumab. Clin Lymphoma Myeloma, 7:125-30.
    • O'Brien, Keating MJ, Mocarski ES. 2006. Updated guidelines on the management of cytomegalovirus reactivation in patients with chronic lymphocytic leukemia treated with alemtuzumab. Clin Lymphoma Myeloma, 7:125-30.
  • 16
    • 0029937765 scopus 로고    scopus 로고
    • Humanized CD52 monoclonal antibody Campath-1H as first line treatment in chronic lymphocytic leukemia
    • Osterberg A, Fassas AS, Anagnosopoulos A, et al. 1996. Humanized CD52 monoclonal antibody Campath-1H as first line treatment in chronic lymphocytic leukemia. Br J Haematol, 93:151-3.
    • (1996) Br J Haematol , vol.93 , pp. 151-153
    • Osterberg, A.1    Fassas, A.S.2    Anagnosopoulos, A.3
  • 17
    • 0030897222 scopus 로고    scopus 로고
    • Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia
    • Osterborg A, Dyer MJ, Bunjes D, et al. 1997. Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. J Clin Oncol, 15:1567-74.
    • (1997) J Clin Oncol , vol.15 , pp. 1567-1574
    • Osterborg, A.1    Dyer, M.J.2    Bunjes, D.3
  • 18
    • 44049096479 scopus 로고    scopus 로고
    • Rai KR, Byrd JC, Peterson B, et al. 2003. Subcutaneous alemtuzumab following fludarabine for previously untreated patients with chronic lymphocytic leukemia (CLL): CALGB study 1990. Blood, abstract 2506, 676a.
    • Rai KR, Byrd JC, Peterson B, et al. 2003. Subcutaneous alemtuzumab following fludarabine for previously untreated patients with chronic lymphocytic leukemia (CLL): CALGB study 1990. Blood, abstract 2506, 676a.
  • 19
    • 44049093137 scopus 로고    scopus 로고
    • Rai KR, Byrd JC, Peterson BL, et al. 2002b. A phase II trial of fludarabine followed by alemtuzumab (Campath-1H in previously untreated chronic lymphocytic leukemia (CLL) patients with active disease. Cancer and Leukemia Group B (CALG) Study 19901. Blood, abstract 772, 205a.
    • Rai KR, Byrd JC, Peterson BL, et al. 2002b. A phase II trial of fludarabine followed by alemtuzumab (Campath-1H in previously untreated chronic lymphocytic leukemia (CLL) patients with active disease. Cancer and Leukemia Group B (CALG) Study 19901. Blood, abstract 772, 205a.
  • 20
    • 0037106502 scopus 로고    scopus 로고
    • Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine
    • Rai KR, Freter CE, Mercier RJ, et al. 2002a. Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine. J Clin Oncol, 20:3891-7.
    • (2002) J Clin Oncol , vol.20 , pp. 3891-3897
    • Rai, K.R.1    Freter, C.E.2    Mercier, R.J.3
  • 21
    • 36048973732 scopus 로고    scopus 로고
    • Incidence of genomic aberrations and associated efficacy from a phase III study alemtuzumab vs. chlorambucil as first line therapy for B-cell chronic lymphocytic leukemia (B-CLL)
    • abstract 2092
    • Robak T, Dmosynska A, Fetni R, et al. 2006. Incidence of genomic aberrations and associated efficacy from a phase III study alemtuzumab vs. chlorambucil as first line therapy for B-cell chronic lymphocytic leukemia (B-CLL). Blood, 108:593a (abstract 2092).
    • (2006) Blood , vol.108
    • Robak, T.1    Dmosynska, A.2    Fetni, R.3
  • 22
    • 0037043653 scopus 로고    scopus 로고
    • Campath-1H induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy
    • Stilgenbauer S, Cohner H. 2002. Campath-1H induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy. N Engl J Med, 347:452-3.
    • (2002) N Engl J Med , vol.347 , pp. 452-453
    • Stilgenbauer, S.1    Cohner, H.2
  • 23
    • 2942694373 scopus 로고    scopus 로고
    • Consolidation with alemtuzumab in patients with chronic lymphocytic leukemia (CLL) in first remission experience on safety and efficacy within a randomized multicenter phase III trial of the German CLL study group (GCLLS)
    • Wendtner CM, Ritgen M, Schweighoffer CD, et al. 2004. Consolidation with alemtuzumab in patients with chronic lymphocytic leukemia (CLL) in first remission experience on safety and efficacy within a randomized multicenter phase III trial of the German CLL study group (GCLLS). Leukemia, 18:1093-101.
    • (2004) Leukemia , vol.18 , pp. 1093-1101
    • Wendtner, C.M.1    Ritgen, M.2    Schweighoffer, C.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.