Importance of arterial stiffness as cardiovascular risk factor for future development of new type of drugs

Fundamental and Clinical Pharmacology

Volumn 22, Issue 3, 2008, Pages 241-246

  Boutouyrie, Pierre ^a,b   Laurent, Stéphane ^a,b   Briet, Marie ^a,b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

Aorta; Artery; Cardiovascular risk; Epidemiology; Mortality; Stiffness

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADVANCED GLYCATION END PRODUCT; ALDOSTERONE ANTAGONIST; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BIOLOGICAL MARKER; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRATE;

ARTERIAL STIFFNESS; BLOOD PRESSURE; CARDIOVASCULAR RISK; CAROTID ARTERY; DIABETES MELLITUS; DIETARY INTAKE; EPIDEMIOLOGICAL DATA; EXERCISE; HIGH RISK PATIENT; HORMONE SUBSTITUTION; HUMAN; HYPERTENSION; LIFESTYLE; LIPID BLOOD LEVEL; MEASUREMENT; MORTALITY; PREDICTION; PRIORITY JOURNAL; PULSE WAVE; REVIEW; RISK FACTOR; SMOKING; VALIDATION PROCESS;

ANIMALS; ARTERIES; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CARDIOVASCULAR AGENTS; CARDIOVASCULAR DISEASES; CAROTID ARTERIES; DRUG DESIGN; FEMORAL ARTERY; HUMANS; PROGNOSIS; PULSE; RISK FACTORS;

EID: 44049092160     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2008.00584.x     Document Type: Review

References (38)

1. Safar M.E., O'Rourke M.F. Arterial stiffness in hypertension. Handbook of hypertension. Elsevier, London, 2006, 598 pp.
2. O'Rourke M.F., Safar M.E. Relationship between aortic stiffening and microvascular disease in brain and kidney: cause and logic of therapy. Hypertension (2005) 46 200 204.
3. Bramwell L.C.H.A. Velocity of transmission of the pulse wave. Lancet (1922) 1 891 892.
4. Laurent S., Cockcroft J., Van Bortel L. et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur. Heart J. (2006) 27 2588 2605.
5. O'Rourke M.F., Pauca A.L. Augmentation of the aortic and central arterial pressure waveform. Blood Press. Monit. (2004) 9 179 185.
6. Agabiti-Rosei E., Mancia G., O'Rourke M.F. et al. Central blood pressure measurements and antihypertensive therapy: a consensus document. Hypertension (2007) 50 154 160.
7. Benetos A., Laurent S., Hoeks A.P., Boutouyrie P.H., Safar M.E. Arterial alterations with aging and high blood pressure. A noninvasive study of carotid and femoral arteries. Arterioscler. Thromb. (1993) 13 90 97.
8. Laurent S., Boutouyrie P., Lacolley P. Structural and genetic bases of arterial stiffness. Hypertension (2005) 45 1050 1055.
9. Zhu L., Vranckx R., Khau V.K. et al. Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus. Nat. Genet. (2006) 38 343 349.
10. Vlachopoulos C., Dima I., Aznaouridis K. et al. Acute systemic inflammation increases arterial stiffness and decreases wave reflections in healthy individuals. Circulation (2005) 112 2193 2200.
11. Maki-Petaja K.M., Hall F.C., Booth A.D. et al. Rheumatoid arthritis is associated with increased aortic pulse-wave velocity, which is reduced by anti-tumor necrosis factor-alpha therapy. Circulation (2006) 114 1185 1192.
12. Roman M.J., Devereux R.B., Schwartz J.E. et al. Arterial stiffness in chronic inflammatory diseases. Hypertension (2005) 46 194 199.
13. Mahmud A., Feely J. Arterial stiffness is related to systemic inflammation in essential hypertension. Hypertension (2005) 46 1118 1122.
14. Amar J., Ruidavets J.B., Peyrieux J.C. et al. C-reactive protein elevation predicts pulse pressure reduction in hypertensive subjects. Hypertension (2005) 46 151 155.
15. Williams B., Lacy P.S., Thom S.M. et al. Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study. Circulation (2006) 113 1213 1225.
16. Simon T., Boutouyrie P., Simon J.M. et al. Influence of tamoxifen on carotid intima-media thickness in postmenopausal women. Circulation (2002) 106 2925 2929.
17. Mattace-Raso F.U., van der Cammen T.J., Hofman A. et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation (2006) 113 657 663.
18. Mahomed F. The aetiology of Bright's disease and the prealbuminuric stage. Med. Chir. Trans. (1874) 57 197 228.
19. Katsahian S., Resche-Rigon M., Chevret S., Porcher R. Analysing multicentre competing risks data with a mixed proportional hazards model for the subdistribution. Stat. Med. (2006) 25 4267 4278.
20. Lloyd-Jones D.M., Leip E.P., Larson M.G., Vasan R.S., Levy D. Novel approach to examining first cardiovascular events after hypertension onset. Hypertension (2005) 45 39 45.
21. Kalantar-Zadeh K., Abbott K.C., Salahudeen A.K., Kilpatrick R.D., Horwich T.B. Survival advantages of obesity in dialysis patients. Am. J. Clin. Nutr. (2005) 81 543 554.
22. Wang T.J., Gona P., Larson M.G. et al. Multiple biomarkers for the prediction of first major cardiovascular events and death. N. Engl. J. Med. (2006) 355 2631 2639.
23. Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 447 661 678.
24. Samani N.J., Erdmann J., Hall A.S. et al. Genomewide association analysis of coronary artery disease. N. Engl. J. Med. (2007) 357 443 453.
25. Mahmud A. Reducing arterial stiffness and wave reflection - quest for the Holy Grail. Artery Res. (2007) 1 13 19.
26. Balkestein E.J., Aggel-Leijssen D.P., van Baak M.A., Struijker-Boudier H.A., Van Bortel L.M. The effect of weight loss with or without exercise training on large artery compliance in healthy obese men. J. Hypertens. (1999) 17 1831 1835.
27. Avolio A.P., Clyde K.M., Beard T.C., Cooke H.M., Ho K.K., O'Rourke M.F. Improved arterial distensibility in normotensive subjects on a low salt diet. Arteriosclerosis (1986) 6 166 169.
28. McEniery C.M., Schmitt M., Qasem A. et al. Nebivolol increases arterial distensibility in vivo. Hypertension (2004) 44 305 310.
29. Boutouyrie P., Bussy C., Lacolley P., Girerd X., Laloux B., Laurent S. Association between local pulse pressure, mean blood pressure, and large-artery remodeling. Circulation (1999) 100 1387 1393.
30. Boutouyrie P., Bussy C., Hayoz D. et al. Local pulse pressure and regression of arterial wall hypertrophy during long-term antihypertensive treatment. Circulation (2000) 101 2601 2606.
31. Lehoux S., Castier Y., Tedgui A. Molecular mechanisms of the vascular responses to haemodynamic forces. J. Intern. Med. (2006) 259 381 392.
32. Tropeano A.I., Boutouyrie P., Pannier B. et al. Brachial pressure-independent reduction in carotid stiffness after long-term angiotensin-converting enzyme inhibition in diabetic hypertensives. Hypertension (2006) 48 80 86.
33. Ramirez F., Sakai L.Y., Dietz H.C., Rifkin D.B. Fibrillin microfibrils: multipurpose extracellular networks in organismal physiology. Physiol. Genom. (2004) 19 151 154.
34. Habashi J.P., Judge D.P., Holm T.M. et al. Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science (2006) 312 117 121.
35. Durier S., Fassot C., Laurent S. et al. Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness. Circulation (2003) 108 1845 1851.
36. Guerin A.P., Blacher J., Pannier B., Marchais S.J., Safar M.E., London G.M. Impact of aortic stiffness attenuation on survival of patients in end-stage renal failure. Circulation (2001) 103 987 992.
37. Devereux R.B., Wachtell K., Gerdts E. et al. Prognostic significance of left ventricular mass change during treatment of hypertension. JAMA (2004) 292 2350 2356.
38. de Zeeuw D., Remuzzi G., Parving H.H. et al. Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation (2004) 110 921 927.