Spiro[(dihydropyrazin-2,5-dione)-6,3′-(2′,3′- dihydrothieno[2,3-b]naphtho-4′,9′-dione)]-based cytotoxic agents: Structure-activity relationship studies on the substituent at N4-position of the diketopiperazine domain
6th ed, Lippincott, Williams and Wilkins: Philadelphia, PA
De Vita, V. T.; Hellman, S.; Rosenberg, S. A. Cancer: Principles and Practice of Oncology, 6th ed.; Lippincott, Williams and Wilkins: Philadelphia, PA, 2001.
The Design, Synthesis and Development of a New Class of Potent Antineoplastic Anthraquinones
Cheng, C. C.; Zee-Cheng, R. K. Y. The Design, Synthesis and Development of a New Class of Potent Antineoplastic Anthraquinones. Prog. Med. Chem. 1983, 20, 83-118.
Gerwirtz, D. A. A Critical Evaluation of the Mechanisms of Action Proposed for the Antitumor Effects of the Antrhracycline Antibiotics Adriamycin and Daunorubicin. Biochem. Pharmacol. 1999, 57, 727-741.
Gerwirtz, D. A. A Critical Evaluation of the Mechanisms of Action Proposed for the Antitumor Effects of the Antrhracycline Antibiotics Adriamycin and Daunorubicin. Biochem. Pharmacol. 1999, 57, 727-741.
7
0033799839
Multidrug Resistance (MDR) in Cancer. Mechanisms, Reversal Using Modulators of MDR and the Role of MDR Modulators in Influencing the Pharmacokinetics of Anticancer Drugs
Krishna, R.; Mayer, L. D. Multidrug Resistance (MDR) in Cancer. Mechanisms, Reversal Using Modulators of MDR and the Role of MDR Modulators in Influencing the Pharmacokinetics of Anticancer Drugs. Eur. J. Pharm. Sci. 2000, 11, 265-83.
Cardioselective and Cumulative Oxidation of Mitochondrial DNA Following Subchronic Doxorubicin Administration
Serrano, J.; Palmeira, C. M.; Kuehl, D. W.; Wallace, K. B. Cardioselective and Cumulative Oxidation of Mitochondrial DNA Following Subchronic Doxorubicin Administration. Biochim. Biophys. Acta 1999, 1411, 201-205.
Cycloaddition Reactions of Thiazolidine Derivatives. An Approach to the Synthesis of New Functionalized Heterocyclic Systems
Gomez-Monterrey, I.; Campiglia, P; Mazzoni, O.; Novellino, E.; Diurno, M. V. Cycloaddition Reactions of Thiazolidine Derivatives. An Approach to the Synthesis of New Functionalized Heterocyclic Systems. Tetrahedron Lett. 2001, 42, 5755-5757.
New Benzo[g]isoquinoline-5,10-diones and Dihydrothieno[2,3-b]naphtho-4,9-dione Derivatives: Synthesis and Biological Evaluation as Potential Antitumoral Agents
Gomez-Monterrey, I.; Campiglia, P.; Grieco, P.; Diurno, M. V.; Bolognese, A.; La Colla, P.; Novellino, E. New Benzo[g]isoquinoline-5,10-diones and Dihydrothieno[2,3-b]naphtho-4,9-dione Derivatives: Synthesis and Biological Evaluation as Potential Antitumoral Agents. Bioorg. Med. Chem. 2003, 11, 3769-3775.
Design, Synthesis, and Cytotoxic Evaluation of a New Series of 3-Substituted Spiro[(dihydropyrazine-2,5-dione)-6,3"-(2", 3"-dihydrothieno[2,3-b]naphtho-4",9"-dione)] Derivatives
Gomez-Monterrey, I.; Campiglia, P.; Carotenuto, A.; Califano, D.; Pisano, C.; Vesci, L.; Lama, T.; Bertamino, A.; Sala, M.; Mazzella di Bosco, A.; Grieco, P.; Novellino, E. Design, Synthesis, and Cytotoxic Evaluation of a New Series of 3-Substituted Spiro[(dihydropyrazine-2,5-dione)-6,3"-(2", 3"-dihydrothieno[2,3-b]naphtho-4",9"-dione)] Derivatives. J. Med. Chem. 2007, 50, 1787-1798.
The Search of DNA-Intercalators as Antitumoral Drugs: What it Worked and What did not Work
Martínez, R.; Chacón-García, L. The Search of DNA-Intercalators as Antitumoral Drugs: What it Worked and What did not Work. Curr. Med. Chem. 2005, 12, 127-151.
A New Amine Resolution Method and Its Application to 3-Amino Benzodiazepines
Rittle, K. E.; Evans, B. E.; Bock, M. G.; Di Pardo, R. M.; Whitter, W. L.; Homnick, C. F.; Veber, D. F.; Freidinger, R. M. A New Amine Resolution Method and Its Application to 3-Amino Benzodiazepines. Tetrahedron Lett. 1987, 28, 521-522.
Enterocyte-like Differentiation and Polarization of the Human Colon Carcinoma Cell Line CaCo-2 in Culture
(a) Pinto, M.; Robine-Leon, S.; Appay, M. D.; Kedinger, M.; Triadou, N.; Dussaulx, E.; Lacroix, B.; Simon-Assman, P.; Haffen, K.; Fogh, J.; Zweibaum, A. Enterocyte-like Differentiation and Polarization of the Human Colon Carcinoma Cell Line CaCo-2 in Culture. Biol. Cell 1983, 47, 323-330.
CaCo-2 Cells Express a Combination of Colonocyte and Enterocyte Phenotypes
(b) Engle, M. J.; Goetz, G. S.; Alpers, D. H. CaCo-2 Cells Express a Combination of Colonocyte and Enterocyte Phenotypes. J. Cell. Physiol. 1998, 174, 362-369.
Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy
Mayer, M.; Meyer, B. Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy. Angew. Chem., Int. Ed. 1999, 38, 1784-1788.
Meyer, B.; Peters, T. NMR Spectroscopy Techniques for Screening and Identifying Ligand Binding to Protein Receptors. Angew. Chem., Int. Ed. 2003, 42, 864-890.
Meyer, B.; Peters, T. NMR Spectroscopy Techniques for Screening and Identifying Ligand Binding to Protein Receptors. Angew. Chem., Int. Ed. 2003, 42, 864-890.
23
29544434772
Differential-Frequency Saturation Transfer Difference NMR Spectroscopy Allows the Detection of Different Ligand-DNA Binding Modes
Di Micco, S.; Bassarello, C.; Bifulco, G.; Riccio, R.; Gomez-Paloma, L. Differential-Frequency Saturation Transfer Difference NMR Spectroscopy Allows the Detection of Different Ligand-DNA Binding Modes. Angew. Chem., Int. Ed. 2006, 45, 224-228.