Independent-model diagnostics for a priori identification and interpretation of outliers from a full pharmacokinetic database: Correspondence analysis, Mahalanobis distance and Andrews curves

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 35, Issue 2, 2008, Pages 159-183

  Semmar, Nabil ^a,b   Urien, Saik ^c,d   Bruguerolle, Bernard ^a   Simon, Nicolas ^a  

^a Medical School of Marseilles   (France)

^b University Tunis El Manar   (Tunisia)

^c CENTRE RENÉ HUGUENIN   (France)

^d INSERM   (France)

Author keywords

Andrews curves; Correspondence analysis; Full pharmacokinetic database; Independent model diagnostics; Mahalanobis distance; Outliers; Variability analysis

Indexed keywords

CAPECITABINE; HYDROCORTISONE; TETRACOSACTIDE;

ARTICLE; CORRESPONDENCE ANALYSIS; DATA BASE; DIAGNOSIS RELATED GROUP; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG RESEARCH; FOURIER TRANSFORMATION; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; JACKKNIFE TEST; MULTIVARIATE ANALYSIS; POPULATION DYNAMICS; PRIORITY JOURNAL;

EID: 43949119111     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-007-9082-0     Document Type: Article

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